HsaINT0027537 @ hg19
Intron Retention
Gene
ENSG00000203697 | CAPN8
Description
calpain 8 [Source:HGNC Symbol;Acc:1485]
Coordinates
chr1:223718134-223718661:-
Coord C1 exon
chr1:223718593-223718661
Coord A exon
chr1:223718213-223718592
Coord C2 exon
chr1:223718134-223718212
Length
380 bp
Sequences
Splice sites
5' ss Seq
CTGGTAACT
5' ss Score
5.45
3' ss Seq
GGATTTCTTTCCTGCTTTAGGAG
3' ss Score
7.98
Exon sequences
Seq C1 exon
AGCAATGGAACGGGCACTTTGGGGGCGGTGGAATTCAAGACGCTCTGGCTGAAGATTCAGAAGTATCTG
Seq A exon
GTAACTCTCTTTTCCTTCTGGGCATCCTCTCCTCTGTTCTAATCCTCCCTTACACTCATTCCTGGTCCATTGTAGTCTGACCACATCCTTAATCATGGTCAAAACTATTGAGTCCTGGGCACATTGGTCACGAAGGAACAAGAAGGCAATGAGAGACTCTCATGCCAACCACTGCCCTGAAAGCCCTGCTGTTCAGACAGCAAAGGGGCCAGCACTGGCCAAGCTCTTATGCTTGCTCTGAAACCTTCTTGGGAGGAGTCAATAGGGTCTCCTTTTGAAAGTGTCCCTGGCCTTTTGAGAAAGCAGTGTGGTGGAGGGAGATGGTTCTGGCAGGGGCCGTGAATGGTTGTTTTCTACTTGGGATTTCTTTCCTGCTTTAG
Seq C2 exon
GAGATCTATTGGGAAACTGATTATAACCACTCGGGCACCATCGATGCCCACGAGATGAGGACAGCCCTCAGGAAGGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000203697-CAPN8:NM_001143962:13
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0003627=EF-hand_1=PD(62.1=78.3),PF134991=EF-hand_7=PU(5.4=21.7)
A:
NA
C2:
PF134991=EF-hand_7=FE(28.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)