HsaINT0037728 @ hg38
Intron Retention
Gene
ENSG00000188986 | NELFB
Description
negative elongation factor complex member B [Source:HGNC Symbol;Acc:HGNC:24324]
Coordinates
chr9:137266944-137267346:+
Coord C1 exon
chr9:137266944-137267086
Coord A exon
chr9:137267087-137267239
Coord C2 exon
chr9:137267240-137267346
Length
153 bp
Sequences
Splice sites
5' ss Seq
TAAGTACGG
5' ss Score
2.1
3' ss Seq
TGATGGCGCCCCGGGCGCAGGTT
3' ss Score
4.5
Exon sequences
Seq C1 exon
GAGGTAGAGCTCATCACCAGGTTCCTCCCGATGCTCATGTCCTTCCTGGTGGATGACTACACTTTCAATGTGGATCAGAAACTTCCGGCTGAGGAGAAAGCCCCAGTCTCATATCCAAACACACTTCCCGAAAGCTTCACTAA
Seq A exon
GTACGGGCTGTAGGGCCATGGTGCAGGGGTGGCCGTGGCGCAGGGATGGCACTGTTGCCCAGGGGGCTGCCTCAGGGCTGGGCAGGGGTCGGTGTGGGGCTGAGGTGGGGCTGAGGTGGGGCTGAGGTGGGGCTGATGGCGCCCCGGGCGCAG
Seq C2 exon
GTTTCTGCAGGAGCAGCGCATGGCCTGCGAGGTGGGGCTGTACTACGTCCTGCACATCACCAAGCAGAGGAACAAGAACGCGCTCCTCCGCCTGCTGCCCGGGCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188986:ENST00000343053:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.035 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF062098=COBRA1=FE(12.6=100)
A:
NA
C2:
PF062098=COBRA1=FE(7.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGTAGAGCTCATCACCAGGT
R:
GAGCGCGTTCTTGTTCCTCTG
Band lengths:
227-380
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development