HsaINT0043554 @ hg38
Intron Retention
Gene
ENSG00000138161 | CUZD1
Description
CUB and zona pellucida like domains 1 [Source:HGNC Symbol;Acc:HGNC:17937]
Coordinates
chr10:122837404-122839231:-
Coord C1 exon
chr10:122839017-122839231
Coord A exon
chr10:122837555-122839016
Coord C2 exon
chr10:122837404-122837554
Length
1462 bp
Sequences
Splice sites
5' ss Seq
TCTGTAAGT
5' ss Score
7.96
3' ss Seq
CACCTTCACATCCATTTCAGCTA
3' ss Score
7.94
Exon sequences
Seq C1 exon
GCTTGATCCAGATGGAAGCTGTGAAAGTGAAAACATTAAAGTCTTTGACGGAACCTCCAGCAATGGGCCTCTGCTAGGGCAAGTCTGCAGTAAAAACGACTATGTTCCTGTATTTGAATCATCATCCAGTACATTGACGTTTCAAATAGTTACTGACTCAGCAAGAATTCAAAGAACTGTCTTTGTCTTCTACTACTTCTTCTCTCCTAACATCT
Seq A exon
GTAAGTCCTCATTTACACAACCTTCACCCACATCTCCTACAAGCACAGGTTACACACTCTTCTGTCCGGGTTCTTATAATCTTCAGTCTGAGTATATTCCCTCAGAGTCTTCTCTATCTGAGAGAGCAGTAGTTCTCTAACTTACATGTGCATAAGAATCATCTGGAGAGCTTGTTAAATCACAGATCCTGGACCCCATCACAGATATTGTGATTCATTGGTTCTGGATGGAGCACATGATCTTGACTTTCTAACTAGCTCCCAGATGAGGCAGAGACAAGGGGCTGATCAGATGGCTACATATTGAGGGGTACTGTGTTAGAGCCCAAAGCGGAGATTCTGCATTCAGCCTGTTTAATAGTAACCCTGGTATCTTCTGCAATGCCTCTTCAGGGACTGCACCTCCCTATGCTCTGATTCCTTAGATCTTGGTTCGGGTTGTTGAACCTTCCTGTTTAACAAGTCCCCCGGATGATTCTGACAAAGAAGACTGGAGAGTGCATGCTGGGAATCTCTGGGCTCACCATTGAAATTTAAGACTGTCAGGTGATTGGAGGCTACATTTACAGGGCTCTGCATTCACAGCACCTACATTCCACTGTGATCCGAAGCAGAATGCCAAGAACATCTGCGAGTGGGTTCATGAGGAGAGCTCCACTGTGGATTTCTTTCCAAGGCCCAGAGCTGACCATGTCACTCTCCTGCTAAAACCACTGACTTCTTGGTACCAGCAGATCTCCAGAGTGCAGCAGTCAAGGTTTTCCCACGCTGGACCCAGGCCACCTTTTCAAGCCTTGCCTCTAGCTGCTGCCTGGCGTGCACCCTATGCTTCAGCCAATCTAAACCATTTTACAGCTCCAAAAAGAGCTCTCTGCATTGTTTCTCCACATTTCATCTGTCCAGCTGCTTCCTTATGTACTTACTGGGGAAAGGAGAGACCAAGGGCTGCTTCATGAAGGCTGTTTCTGAGCTGAGCTTTGAACAATAGCATGACGAGGGTAGGTGGAGGTGGGAGTCAGGGAAGAGGACTCACCTCTGCTGGAGCTGACAGCTGAGGAGTCATGGGAAGAAAGGGAGGATAGAACAGAAGGCCATGAAGTAGTGGCGGATGAGACTGGAAAGCTGAGCTGGTGAGAGTGAGGAAGAGCCTTCAAGGGAGGGTGTGACTTTATTTTCTATGGCGCAATTCAGGTAATGGGAGTCTCTCCAGATGCAACACATGTTACAGCACAACTTTAATATGATTCGTTTGGCAATAGTATAAAGATTCCCTCTCTGCCCTGCACCAGTGGACAGAAATTTCAATGATAAAAAAGGATGAAAACCTCAATATGTGACCCATGGGAAAGATAGAGATGGAATCATACTCAGGAGAGATGTGTTAAGCTCAATGCACAACACAGAAATTAAAAGCAGTCTCTATTTTGATGTTCATTCTTGACCACCTTCACATCCATTTCAG
Seq C2 exon
CTATTCCAAACTGTGGCGGTTACCTGGATACCTTGGAAGGATCCTTCACCAGCCCCAATTACCCAAAGCCGCATCCTGAGCTGGCTTATTGTGTGTGGCACATACAAGTGGAGAAAGATTACAAGATAAAACTAAACTTCAAAGAGATTTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138161:ENST00000368904:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0043115=CUB=PD(69.1=89.0)
A:
NA
C2:
PF0043115=CUB=PU(42.2=90.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCAGATGGAAGCTGTGAAAGTG
R:
CTTGTAATCTTTCTCCACTTGTATGT
Band lengths:
334-1796
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development