HsaINT0044234 @ hg38
Intron Retention
Gene
ENSG00000197408 | CYP2B6
Description
cytochrome P450 family 2 subfamily B member 6 [Source:HGNC Symbol;Acc:HGNC:2615]
Coordinates
chr19:41012298-41012815:+
Coord C1 exon
chr19:41012298-41012485
Coord A exon
chr19:41012486-41012673
Coord C2 exon
chr19:41012674-41012815
Length
188 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGA
5' ss Score
10.57
3' ss Seq
ATCTTGTGATCCTCCCTCAGGAC
3' ss Score
8.54
Exon sequences
Seq C1 exon
AGAGAGTCTACAGGGAGATTGAACAGGTGATTGGCCCACATCGCCCTCCAGAGCTTCATGACCGAGCCAAAATGCCATACACAGAGGCAGTCATCTATGAGATTCAGAGATTTTCCGACCTTCTCCCCATGGGTGTGCCCCACATTGTCACCCAACACACCAGCTTCCGAGGGTACATCATCCCCAAG
Seq A exon
GTAAGACCGGCTGGAACCCCATAGCCCTCCTGTTTGGGCATCCTGGATTCTCTTAATCCCCGAACTCAACCTTTTGTTAGCTCCTTAATTGAGTCCCGTTGTTTTTGTTTTTTGTATTTCTTTTTTGTGGAGTGTGTGGAGGGTTGGAGGGAATGGCAATATCTTTTGATCTTGTGATCCTCCCTCAG
Seq C2 exon
GACACAGAAGTATTTCTCATCCTGAGCACTGCTCTCCATGACCCACACTACTTTGAAAAACCAGACGCCTTCAATCCTGACCACTTTCTGGATGCCAATGGGGCACTGAAAAAGACTGAAGCTTTTATCCCCTTCTCCTTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197408:ENST00000324071:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.111 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006717=p450=PD(1.1=1.6),PF0006717=p450=FE(36.7=100)
A:
NA
C2:
PF0006717=p450=FE(10.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGAACAGGTGATTGGCCCAC
R:
GTCAGGATTGAAGGCGTCTGG
Band lengths:
251-439
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development