HsaINT0044261 @ hg19
Intron Retention
Gene
ENSG00000138115 | CYP2C8
Description
cytochrome P450, family 2, subfamily C, polypeptide 8 [Source:HGNC Symbol;Acc:2622]
Coordinates
chr10:96827286-96829254:-
Coord C1 exon
chr10:96828992-96829254
Coord A exon
chr10:96827449-96828991
Coord C2 exon
chr10:96827286-96827448
Length
1543 bp
Sequences
Splice sites
5' ss Seq
AATGTAAGT
5' ss Score
8.62
3' ss Seq
ATTTGCATTTCCTTTCCCAGTTC
3' ss Score
9.18
Exon sequences
Seq C1 exon
ACATGTCAAAGAGACACACACTAAATTAGCAGGGAGTGTTATAAAAACTTTGGAGTGCAAGCTCACAGCTGTCTTAATAAGAAGAGAAGGCTTCAATGGAACCTTTTGTGGTCCTGGTGCTGTGTCTCTCTTTTATGCTTCTCTTTTCACTCTGGAGACAGAGCTGTAGGAGAAGGAAGCTCCCTCCTGGCCCCACTCCTCTTCCTATTATTGGAAATATGCTACAGATAGATGTTAAGGACATCTGCAAATCTTTCACCAAT
Seq A exon
GTAAGTCTGCCTTATGTTCCTCCAGCCAATTGCAAAGGGTAAGTTATTTGACTGCTATTTTTAGACAAAATATATTCCTGGAAGCACACTATTATAATAGATCATTGTAAAGCAAAATACTCCCTCTGAACTTCTTTGATGTTTCTTTTGTCTTCCTATTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTATTGCCCAGGCTGGAGTGCAGTGGCACTATCTCCACTCACTGCAAGCTCTGCCTCCCAGGTTCACACCATTCTCCTGCCTCAGCCTCCCCCGAGTAACTGGGACTACAGGTGCCCTCCACCATGCCCGGCTAATTTTTTGTATGTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGAATGGTCTCAGTCTCCTGACCTCATGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACATGTGTGAGCCACCGTACCTGGCCTCTTTTGTCTTTCTAAGTCTGTCATTGTCAGAAATAGCGGAGTGAGTTGATGCATTTTGTGAATACAGAAACATTGGGGTCATTGTATTATATAATCATTTAATACAGTGGCAAAAGTTTAAAGTGCTGTTTCTCCTCTTTGTTTCACAGTGTTTTGCTATGATTTTTGACTGAAGGTGAAGGGAAGTGTGTGTGATTAGAAATTTCATCCAATAAGTTCTCTACTATAGTAGTCATGTGTTTTATTCAGAATGGTCATGAAAATTGAACTTCTCTGAAGATTCATTTGATGGCTGATGTGAAATAAATATCTGTGGGTTCAGGGCAAACATAAGTGCATGAAAGAAAGAAGTAATCAGTCAGGGCCCAATAGGTAGTTAACAGAATTCTTTTGGATTCTGAAGAAAGCCACTGTCTGTGGCCAAGGTTGCTGGAGAATGGAAGAAATTGTTCTTCCAGGAGATGCTGAATGTCCTGATTCTAACTTTGTGGTGCTTCATCGTTCCATATTGGTAATACCAGCAGTTACAAACTGGACTGGGCATTAGAATCACCTGGGGTGACACTGTAAATACAGATTTCTAGGGTTCATCACAGGACTGCTGTATCAGAATCCTCATGTTAAGAGCTTTACAAGTGACCCTGAAGTCTTTAGCTGGGTAGTGGCCTCAAGGTGGACATGGGGGATTGATTAATTGCTCAAGCATCAGTTTAAATTAGCAGAGATTCCAGTTTGGAGCTTCTACATATTACCTGTGGGACTCTGAGAATGAATCTGCAATTCTCTGGCCTCAGTTTCTTCATTTTTAAAACAGGTCAAATGAATGTGCTGAATGTGTTGAAGTGAGGATGAACTGTGTGATTTGTGTACCAATTGCCTGGGTCATTGCGTGGCACATCACAGGCCATCTATAAGTGGCAGCTATAACAATCACCATCACATTTATGTACAAAATTCAGAAATATCGAATCTATGTGTGGCAAATATGAACATTAAAAAATACAATGAAAATGTCAGTCTGAATCATACATAGTATTTGGAGCAAATAGCGACTTATTTTGCTGCTATTTGCATTTCCTTTCCCAG
Seq C2 exon
TTCTCAAAAGTCTATGGTCCTGTGTTCACCGTGTATTTTGGCATGAATCCCATAGTGGTGTTTCATGGATATGAGGCAGTGAAGGAAGCCCTGATTGATAATGGAGAGGAGTTTTCTGGAAGAGGCAATTCCCCAATATCTCAAAGAATTACTAAAGGACTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138115-CYP2C8:NM_000770:1
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.018
Domain overlap (PFAM):
C1:
PF0006717=p450=PU(5.7=46.4)
A:
NA
C2:
PF0006717=p450=PD(23.1=75.0)
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTTTGGAGTGCAAGCTCACA
R:
TGGGGAATTGCCTCTTCCAGA
Band lengths:
352-1895
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)