HsaINT0044527 @ hg19
Intron Retention
Gene
ENSG00000186526 | CYP4F8
Description
cytochrome P450, family 4, subfamily F, polypeptide 8 [Source:HGNC Symbol;Acc:2648]
Coordinates
chr19:15728811-15730354:+
Coord C1 exon
chr19:15728811-15728955
Coord A exon
chr19:15728956-15730300
Coord C2 exon
chr19:15730301-15730354
Length
1345 bp
Sequences
Splice sites
5' ss Seq
CAGGTACTC
5' ss Score
7.04
3' ss Seq
ATGGTCCTCATTCATGTCAGATG
3' ss Score
6.91
Exon sequences
Seq C1 exon
GTCACTCCCACAGAGGAGGGCTTGAGGGTCCTGACCCAGCTGGTGGCCACCTACCCCCAGGGCTTTGTGAGGTGGTTGGGCCCCATCACTCCCATCATCAACTTGTGCCACCCTGACATCGTCCGATCTGTCATCAATACCTCAG
Seq A exon
GTACTCCTGCAGAGCTTGTGGTGGTGGGCACAGGAGAACATTGGAGGGCTTCTAGATCTCATCCCCAAAGCTTCTGTGCAGCTCTTGTAGTACTCAGCCCCTTCCTTCCTGCTTCTCTCTCAGCCACCTTCCTCTTTCCTTCCTGTAGTCACCAACCCCAACCTCAGTGTCTTTTCTCTCTGCTGCCATCTTCCCCACCTCCGTGTTGTTCTGGGAACCACTGGGGCCCCGAGAAGCCTTAATCCAAGGCCCTGTCCTGGAGGAATCCCCAAACTTGAAGAGATGGAGCAGTACAGAGACATCCCCAACTTCATGGGGTTCAGAATGGGCCAGGAGGAGATAGGCTGTGACAGAGCATAGGAGAACAAGGTTTCTACTGGGGCAGGCTGGAAGGCTTCCTGGAGGAGGCGTAGCAGGAGCTGGGTGTGGAACGATGAGTGATAATTTTTTTTTTAAAGCAGGGGCAGGGTGATGCAGTGGGCATTGTTAGTATTCAAGGCTCCGGGCCAGGCTTGGCATTGGCCTTGTCCTTCTGCAGGCCCAGAGCAAGGACAAGAAGATGAGAAGGAGTTGTGGTTGGTGGAAGATCTAGGCTGCTATTTCCATGACATTCACCTCTTGTGGGTCGATTCCTTCTAATCCCATCCTGTGGCACTTCCACCATATGTTCATTGCCCTCTTGCTCCAGGCCCCAGGAATCTCCAATAGGAGACACCACCCCAGCCTGGAGCCGTACCCTTGCCCTCTGCCCTTCCCATCTTTGGACAGGCCAGGGAGAGCAGCAGAAGGGGTATCACGCCACAGAGACCATGGCTCAAGCCCCAAAATGCTGAGTGACTCTGGGCAGGTCCACGGCTCTCTATGGGTGCTGAGGTGTCTTTCCATTGTGAGTGGTAGAAACTCAACCCCACGCAGTCTAAGCCATTAAAGAGAAGCTATTGACTGCAACATCCAGGGAGGTTGGCCTTCAGGCACAACTGGATCCAGGTCTCACCTAATATCATCAGAATTCTGTCTTTAACTCTTATTCTGTAAATGTGTTTTGTAGAGTGTTGACTTATGCTTGGGTGTTGCAGAACATGTTGGACCATGTAGGAGCCATGTCAAGACATGCTGGGTGTGCTGTACCATGTCAGGGTGTATCATTGCTCTATAGTGTTGTTGCAGCCTAGTCCGGTCCCCTTTATGCCCCCCACCCTCCTTTCTTCTTCTGCCCATGGCCTCCTTCCTGCTATGCTGGGCTTGGAGAAAAGACGTCCAAACCTCTGGCTGGGAGCCACCCTCCATACCCAAAGTCCCTCCTCTATTCCTCTCCATGGACCCTGATGGTCCTCATTCATGTCAG
Seq C2 exon
ATGCCATTACAGACAAGGACATAGTCTTCTACAAGACCCTGAAGCCCTGGCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186526-CYP4F8:NM_007253:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.004 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NA
A:
NA
C2:
NA
Main Inclusion Isoform:
NA
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCCCACAGAGGAGGGCTTG
R:
CCAGGGCTTCAGGGTCTTGTA
Band lengths:
191-1536
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)