HsaINT0044648 @ hg19
Intron Retention
Gene
ENSG00000115165 | CYTIP
Description
cytohesin 1 interacting protein [Source:HGNC Symbol;Acc:9506]
Coordinates
chr2:158283863-158287164:-
Coord C1 exon
chr2:158287071-158287164
Coord A exon
chr2:158283933-158287070
Coord C2 exon
chr2:158283863-158283932
Length
3138 bp
Sequences
Splice sites
5' ss Seq
AACGTAACT
5' ss Score
6.72
3' ss Seq
TTTTTTTTTCCTTAAAACAGGAT
3' ss Score
9.57
Exon sequences
Seq C1 exon
GTGATGTCCTTGCAAATATCAATGGTGTGAGCACAGAAGGTTTTACCTACAAACAAGTCGTTGACCTGATCAGATCGTCCGGAAACCTGCTAAC
Seq A exon
GTAACTATCTGTCTAGTTCCCGTGGGGCTTCAAAATGTTATGTTTTCTCATAAAGCCTGATGAGTGAATAAATAGGCCTTTTGTTCAGCATTACAAGACGGAGTGAGGCAGTGCACCGGAGCTTTAGAGTGGGGTACAAACATTATCAGTTCCTTTTGTTTCTCAAGATTCCTCACACTTGAACATACTGTCAACATCTGAAGTCAGAGGACATCAATAGCCCAAACGTCTGTGTGGGAAGGATGGCCTTTACAAATGTATTTTTTTAATGTCAAATTCAATTAAACTGGCACACATTCTCTTTAAACTGGGAAGAACTGATCCAATTTTCATGGTTGATATAATCCTGTAGCTAAAACAAATCAAAGGTCAGAAGGGCTGAGTTTTTCCTCTTATGTGACAAGCCACCTGTTTTTCTCTTCTAGTGTTCCATTTGGAAGGAAGAATAGTCTGTTCAACCCTCCCCACCCTGAAACACACATACTCACACCACATGTTCCAAATGTTCCAAACTTCTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCTGGATGGAGTGCAGTGGCGCGATCTTGGCTCACTGCAAGCTCTGCCTCCCAGGTTCACGCCATTCTCCTGCCTCAGCCTCCCTAGTAGCTGGGACTACAGGCGCCCACCACCATGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCATCGTGTTAGCCAGGATGGTCTCAATCTCCTGACCTCATGATCCACCCGCCTCCGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCCCCTGGCCCCAAACTTCTTAATAGAACACTGGCTTTCCCAATTAGAGGTTTGACTGATTTTTCTACCATAACAATACTAGCACCTAATAAAATCTTATTAGGATAGTTAAATGATGAAATTCGCTCATTCATTAAAATCATATTTATTGAGCAAATACTATGTTTCCAGCTCTGTGATAGGCTCAGGAGAGACGAAGATAAAGACTCTCTTAGTACGTTAATAGTTATGGAAGGAAATGGCTCAGAAAAGCCTGAAATTTAAGTAATGTGTATATTTCAGTTATTGATAACTACTATGAGAAAAGTGCAAAACAGCAATGGCCTGTCATGCTAGGTAAGAAGGCTGCTAGTTTGGCTTAGATGTGTAAAGTGGTCTTTTCTAGGGAGGCGATATTTGAGTTGAGATCTAAATGAAGAGAAGGATGGTCAAATGAACTCCTCGTAAGAGCACTTCAGGCAAAGAGAGAGGTCTCTGAGTGCTCACAATGGGCTTGGCATGTACAAGGGAAAGAGAAAAAGACAGTATAATTGGTATTTGATGGATTAGAGAGGGTATAATAAGAAATGAAGCCAGAGAGTTGGCCTGGGGGCAGACCATGGATCTCTTTGGACATGCCAACAAGTTTGGGTTTTATTCTGATTGAGGTGGGTCATATATTGTGTCATTTATTCTTCACAGCCACCCATGAGGTTAATTTTATTCCTATTTATAGATGAAGTGCCTGAAGCTTAGAGGGGGCTTAGTTAAGGTCACATAACTGGTAAGTGATAGGGCTGGGGTTTGACCACCTGCTCTGGATGCCAGGATCTGTCCTTTTCAGCTACAGCTGCTCCTTGGAAGCTGCCAGTAGAAAATCTGCTGGATGCTTTTCAGTGATTCTGGTGTAAAACTTCAAAGGATGCTTTGGGTGTTTGTGAGAGCAGATTTGAAAGATGGTGGTGGTAACAAATTGGGTCCAACTCTATAGGTCCTGTGAGTTCAGGGTAAAGGATGAGGTGCTTTTGCTCTAGAGAACCCTGGATCCAAAGGAGAGGAACCGTGCAGAGTCTGAGGGGAACTGCTGGTAGTTAGAGTCAGAAAGCATGTTCCACATGGGTGAAGAGGGTAGACCACAGGTAAATAGGGGTTGTAGATGGAGGTAACTGTTGGAAATCCGGGAAAATGGGAGACAGTCTGTACAAATACTGAGGAAAATGGCCAAATCAATGGTTGCAGTTTTGCCCATACACATCTATTGCTTCAGCAGGTCAAACTGACATTCAATCCCAATGAAACAGATTCATATGGATTCCCACTATTTCTCAGAGAGTCAAGATCACCTTAAGGAGAAAACAGACAGTATATAGCTTGCTACCACCTGATTATTCCTGGCATGATGCTATTAGAAGTAGAAGACTGATCTCCACATTTAATGCTTTTACCATGCCTTGAAAAATTCCTTGCATCTTTATAGAGAGGTACAGCTTAATTACAAGAAGGAACTTGAACCAACACTTTAAAAATTGGTGTGTGATTCACAAATGAAATTTTTAAATCATATTCAGATTGATGGTTTAGTAGTCAAAATAAAAGCCTTTAACTTGAACACACAGAACAAATCAAATCACTCAGAATAGAACAAGTATTTTATTTTTAGAAATGTGTGTGGTGTGGGAAGAACAGAACACTGGTAAGTTGATAATTCTAGGATTAGAGTTTGTAAACTGAATGTTTTGAGATAAAGAATCATATGAAGGTTATTATGTCATAGTAGTTGTACTTCTGTTTCTTCTAGTACCAAAATTATAAGGAGATTTACAGAGGTAAAGGCTCCTAGAATCCTATGGAGGAAAGGATTTCTCCCTCTTTCAAGAAGTAGCATGTTAATTCCATGGTTGTGAAAGCCCCTAGAGCCTATTATTTCTGTTGTTGTGCCCCTTGTGTTCAGCATGGTTTCTAGAATCTGGTACATAGTAGATGCCCAATAAATATTTACCAAATGAGTGAGGTCATTCAGCCCATCCCCACAAGAACAGATTCTAGTAGAGAGCAGCCATCATTGTCACATAGTGACTTCTATAAAATAAGCTATAGTTTACAAATTAACTAGGATCCTTTCTTTTAGCCACCTTCTCAAGGGGAGTTTTCCCCCATTTTCTTTCTCTGTTATCAGAAGATTTGGCTTTGGTCCAGCTACTCGAAGTGCCATGAGAACTGTAACATTTGTATTTCGTTTTTAGTATAGTATGTGCTCAAAGTGTAGTACTCTGTAGTATGGTACTTATTTAAACGAATCACTCATGTTACTCACTCCCCACCTTCCTCTTCTTTTTTTTTTCCTTAAAACAG
Seq C2 exon
GATAGAGACTCTTAATGGAACAATGATTCTGAAAAGAACGGAGCTTGAAGCAAAGCTGCAGGTTTTAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115165-CYTIP:NM_004288:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0059519=PDZ=FE(35.6=100)
A:
NA
C2:
PF0059519=PDZ=PD(4.6=16.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)