HsaINT0046732 @ hg38
Intron Retention
Gene
ENSG00000205744 | DENND1C
Description
DENN domain containing 1C [Source:HGNC Symbol;Acc:HGNC:26225]
Coordinates
chr19:6478783-6479056:-
Coord C1 exon
chr19:6478937-6479056
Coord A exon
chr19:6478853-6478936
Coord C2 exon
chr19:6478783-6478852
Length
84 bp
Sequences
Splice sites
5' ss Seq
CAGGTGCGG
5' ss Score
9.13
3' ss Seq
CCTGTCTCCTCTCTCCACAGCCA
3' ss Score
12.5
Exon sequences
Seq C1 exon
GGAGCCCCCCAGCCCCGCCGTGCAGCATTTCACCTTCGCCCTCACAGACCTTGCCGGCAACCGCAGATTTGGTTTCTGCCGCCTGCGGGCGGGTACCCAGAGCTGTCTCTGCATCCTCAG
Seq A exon
GTGCGGGATATGGGGGTTGGAGGGGGGGATGGGAAAGGCCGAGGCCTAGGGACACTTCGTGGAACCTGTCTCCTCTCTCCACAG
Seq C2 exon
CCACCTGCCTTGGTTCGAGGTGTTTTACAAGCTATTGAACACAGTGGGAGACCTCCTAGCCCAGGACCAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000205744:ENST00000381480:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.014 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0345613=uDENN=PD(65.9=70.7),PF0214116=DENN=PU(20.9=22.0)
A:
NA
C2:
PF0214116=DENN=FE(11.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCGTGCAGCATTTCACCTTCG
R:
GGAGGTCTCCCACTGTGTTCA
Band lengths:
159-243
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development