HsaINT0049287 @ hg38
Intron Retention
Gene
ENSG00000197653 | DNAH10
Description
dynein axonemal heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:2941]
Coordinates
chr12:123933331-123934766:+
Coord C1 exon
chr12:123933331-123933511
Coord A exon
chr12:123933512-123934620
Coord C2 exon
chr12:123934621-123934766
Length
1109 bp
Sequences
Splice sites
5' ss Seq
AAGGTACCG
5' ss Score
9.67
3' ss Seq
TCTCTGCCTTGTGTCCCTAGGAT
3' ss Score
13.26
Exon sequences
Seq C1 exon
GTGACCGAGAGCGAGCCCAGCGTGATGTGGCTCTCGGGGCTGCACATCCCTGAGTCCTACCTCACGGCGCTGGTGCAGGCCACCTGCCGGAAGAACGGCTGGCCACTGGACCGCTCCACCTTGTTCACACAAGTGACCAAGTTCCAGGATGCAGATGAAGTGAATGAGCGGGCGGGACAAG
Seq A exon
GTACCGTCAGCTCGTTAGGGATCCACAGCCTCTCACTTAGGATTTCTCTCCCTGAACCACCTCCAACTCAAAGGGACAGGCATAGCGTGGGCCTAAATGGGCCAGGCCATGTTTGAAAGCCAGCCTGCTGCAAATATTTCCTGTGTCTCTGCACTGCCCATGTCTTAACACCTCTGAGGGTGGATACGGAAGTTTCTCTTCCACTTTCTCCGTTGAGACCTGGGGTCTATGGCAGGGGAGACCTGAACCATGTTCACTCTGCTAGCTCATGGCAAGTGGGCTCCTAGGTCAGAATTAGCTCTTGCAAAAACCATCAGGTGGCTTTCTTGTAACCCCTGACGGGGCCAGGGGCATGGGAGCCACAGAGCAGCATGGACTAACTTGGTTGGAACTCTTTGATTATGCCAGAACTTCAGGTCCCTTAGACATTGGTTACTGACTGTGCAAATGAGAGCTGGAAACTGCTGTTTCCCCGGGTCCATGTTGTCTTAGAGTTCTTTTAACTGCAAGGAACAAAAGCTCTTTTGAGATGGCTTAAGGACTGGGGACTTACGGTAAAGATGCAGGGACTCTCCAGGTCTCAGTGGCAGGGGAGGTGGCAGGTGTCCGGGCCACCACTCTCTCTGGGGCCACAGGAGTGTGTTCCTCTCTTTGCACATCTGCTGGGTCCTCCTCCCCGGAGACCACTTTCTCTGTGAGGCTTCGACTTCCTGCTCCCCAGCCACTTCGGCTCACAGGGTAGCTGGGGTTGCCATGGTGCCCATTCTGACTCTGGGACCATGCATCTTTCTAGCCTGGGGGCCCAGGGTGGTCTAAGTCCGTGGGCCTTGATGCCCCAGGAATGAGGATTCCTGGGGGAGAGGCCACCGCCCCACACCCATTTCTCTGGGCCATGGGGCAGGGCCACAGGGTCTCCTGTCTGGGCTGCTCCTCCACAGAGGGAAGGTGGGCAGGACAGAAATGCTGGAGAAGGGCCTGGGCTGTCCCCAATGCGCTGGGGAGGAGGCCAGCCAGTGGCCTGTGTGTCGCTGTGTGTGCGCCTGATAGAGCCACTCCGTGGCAGGCTGTGCATGCTCCAGTTGTATCCAGTCTCTGCCTTGTGTCCCTAG
Seq C2 exon
GATGCTTTGTCTCAGGACTGTACCTGGAAGGTGCTGACTGGGATATAGAAAAAGGATGTCTTATCAAGAGCAAACCCAAGGTGCTGGTTGTGGACCTGCCGATCCTGAAGATCATCCCCATTGAAGCCCATCGCCTCAAGCTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197653:ENST00000409039:76
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(8.4=100)
A:
NA
C2:
PF0302810=Dynein_heavy=FE(6.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACCGAGAGCGAGCCCAG
R:
CGATGGGCTTCAATGGGGATG
Band lengths:
312-1421
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development