HsaINT0049358 @ hg38
Intron Retention
Gene
ENSG00000105877 | DNAH11
Description
dynein axonemal heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:2942]
Coordinates
chr7:21864535-21866663:+
Coord C1 exon
chr7:21864535-21864657
Coord A exon
chr7:21864658-21866469
Coord C2 exon
chr7:21866470-21866663
Length
1812 bp
Sequences
Splice sites
5' ss Seq
AAGGTATGT
5' ss Score
9.79
3' ss Seq
GTTTCCCTATCATATTACAGGCA
3' ss Score
7.98
Exon sequences
Seq C1 exon
ATTTTGTTGAGAAAGAAAGAGATAGACCCTCTTGAATTGGATTTCCTGCTTCGATTCACAGTTGAACACACTCATCTGAGTCCCGTTGACTTCCTAACTTCTCAGTCATGGAGTGCTATCAAG
Seq A exon
GTATGTTAGGAATACAGTTTCTCAAATTCTGGATCTTATTTAAAATATTAGCTCTCTCCAGTGTTGAAATGTAAACATTAAAGAATACAGGTGATGTATTAAGCACCATTTCAGTTGTAGAAATGCACTGTATAATGTGATGTTATTAATCTTTGTATTATTCAATTGGTTAATTTCTCATTTAGATGTAAAGGAGCTTTTGGCTTATGTATGCGTGGAAAAGTTAATAAATATGTACAATCTGTCAGGACCTTTGATAAAAGCCAAGTGATACAAATGAATATTTTTAAAAAGTTCCTTAAATCTAAAATTTGTTTTCTTTTTAAATTTCCTTAAAAATTTGTTTTCTTTTTAAATCGTTTCACCATTTTTCTAAATAGTTCTTTAAATTACACCACAGTGGAGTCGTTTATTCTCATTGTAAAATGTTTAAGAAAAACAGAATATTTTAGAGAAATAAGTGACAGTTGCCTTAAACCTCAATTATCAATCCTCATTGCATTTTTCTGTCAAAGGCCCTATTGTTAGAAGTTAATTCTTCCAGGATCTGGAGTATCTTAATGATGTTCAACATATGCTAAGCTTTGCCCTACTCTTTTTTCTAAGAAGGAAACATTTCTGTGCATTGGAAATAACTGTTACCTCTTATTTTTATATATGTTCAGCTTTTTAAAGTAGTATTTGTAATTAGATTGTAACTTTAGAATTCAAAATTCAAATTCAAATGTGTATCAGTCAGGGTCTTAACAGGAAACAGATGGCACATTCAAAAGGTTGATGAAGAAAGTTTAACCAAGAGTCTGTTTTCATAGTATGGGCAAGAAGGATTAGGAAATCAACCAGGGGATGGGGAAGGAAAAAGGAGGAAAAGGACAGTTACTGGAACTTCATAAGAAATGAAGTTATGGGAGAGAGCCAACCTTAGAGGATCTGTGGCCTGTGGCAGAGAAACATAGTCCCTCCCAAACCACATTCCCACGAGAAAGAGCTGGGGTAGAAATGTTTCCAGAAAGGGGTCCTGATCCAGACCCCAAGAGAGGTTCTTGGATCTCGTGCAAGAAAGAATTCAGCGTGAGTCTGTAAAGCGAAAGCAAGTTTATTAATAAAGGAATAAAGAATGGCTACTCCATAGGGAGAGTAGCCCTGAGGGCTGCTGGTTGCCCATTTTTATGGTTATTTCTTGTTGATATGCTAAACAAGGGGTGGATTATTCATATCTCCCCTTTTTAGACTTTATAGGGTAACTTCCTGACGTTACCATGGCATTTGTAAACTGTATGGCACTGGTGCAGTGTAGCAGTGAGGACAACCAGAGGTCACCCTCATCACCATCGTGGTTTTGTTGGGTTTTAGCCAACTTCCTTACTGCAAGCTGTTTTATCTTTATGACCTGTATCTTGTGCCAACTTCCTATCTCATCCTGTGACTTAGAATGCCTTAACCTCCTAGGAATGCAGCCCAGCAAGTCTCAGCCTCAATTTACCCAGCTCCTATTCAAGATGGAGTTGCTGTGGTTCAAACGCCTCTGACAGAAGTACCCCCACCTCTCTCTTCTCCAGTCTTCCAGGCTCCTGCCATTGCTTTCTGTTGGCCAAACCCAACTAGGTCAGGGAACCAGGGAACTCAGCTCAAGTGTCCTTTGAGCTTACCCTCTCAGCAGAGCAAAAAAAAAAAAAAAGGAAATCTGAAGAGGAGAGTGAATACTATCCAGCACAGTTTTTTTACATAAGATTAGATACATTCACAAGTCTTCTTCTCAAACTGTAAAGTATCGTTCACACCATTCCTACTTGTTTCCCTATCATATTACAG
Seq C2 exon
GCAATTGCCGTCATGGAAGAATTTCGAGGCATAGACCGAGATGTGGAAGGATCTGCCAAGCAGTGGAGGAAGTGGGTAGAATCCGAGTGTCCAGAAAAAGAAAAATTACCTCAAGAATGGAAGAAGAAAAGTTTAATACAGAAGCTGATTCTTCTGAGAGCAATGCGCCCTGACAGAATGACGTATGCTCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105877:ENST00000409508:70
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=PU(2.8=48.8)
A:
NA
C2:
PF0302810=Dynein_heavy=FE(9.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGTTGAGAAAGAAAGAGATAGACCC
R:
GAGCATACGTCATTCTGTCAGGG
Band lengths:
310-2122
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development