HsaINT0049363 @ hg38
Intron Retention
Gene
ENSG00000105877 | DNAH11
Description
dynein axonemal heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:2942]
Coordinates
chr7:21880702-21884410:+
Coord C1 exon
chr7:21880702-21880893
Coord A exon
chr7:21880894-21884290
Coord C2 exon
chr7:21884291-21884410
Length
3397 bp
Sequences
Splice sites
5' ss Seq
AAAGTAAGT
5' ss Score
9.72
3' ss Seq
TTGTGTGGTTTTCTCCACAGGTC
3' ss Score
12.97
Exon sequences
Seq C1 exon
GATACACTTGAAATATGCTCCAAGGAGCAGGAGTTTAAAAGCATCCTTTTTTCTCTCTGCTACTTCCACGCCTGTGTTGCTGGGAGACTGAGGTTTGGCCCCCAGGGCTGGAGCCGAAGCTATCCTTTTAATCCTGGAGACCTCACCATTTGTGCCAGTGTCCTCTACAACTACTTAGAGGCAAACTCTAAA
Seq A exon
GTAAGTGCTAGTGGTCAAATAACCTCTTCCAAGGAGTTTACAAAGCTGTCAGTCTTTGGGCACTATCAAAATTGACCATAATTTCTCTTTTGAAGCTATTATTGAAATAGCTGACACTATGTATGTATCTTCTGCCAAGTGTGAAAATAAACCAGATCAAAGGTTTTCCAGCAGTGGATGTTTGCACTTCATGAGATAGGTCAAACCAGTTCTACATCAGCAGCTTAGTGTAAAAAAAAACAAAAAATGTCCTTCATTATGTTAACAAAAACAGTGGTTTACATGTGCGTATATGCCAGATTCATTAGGCAGGTAATGAAGCATTTGCACAAATGTAATTACATACAGCAATTCTGACAGTTCATAACACTGCATTAATAATCACTACAATTAGTTCTGATGATGGAAGCAATTTACAGCGCGTCACATGTATAAATAATGGTGCATTTCCTGCATATGTCATTATTATGTATTAAGGATGCCACCTTGTTGTGACTTTCTCAGTAATGTTCCCCTTGATTTGAAGTTAAAGGTAGATGAATGATTTTATTTCGTAGCTAAAATGTGTTTTACAGATGGGAATGGGAATGCCTCATCAAGAACATTTGTGTAAGTTCTCATAAACCCAATGATTGGATTTCAAAAAGCAAGAACCATTCATTCCTAAGGATTTTCTAGCTTAATCCTCACAAGGGAAACTTTTTTCATTAAGTTAAATCCGTTAAGACTAGGATACATGTGTCAAAACCAGTCAAGTGTTGTACTCTAGGCCACATTTTCTATAAAGCGTTTTTAAAATCACCCGTCTCTGTTTCTAAATGGAAACTATTGTTTTATGTTCCTTCAGTAATGATTGTTATAACTTTTTTGGTCAGCTTTCTCAGGCTTCGGTGGTGATTTGATTGCTATTAGAATAGATACCCTTGGTACCTAACAGGCATATTTTCCCAAGGAACAAATTTTAAATAAGTTGTATCCAAAATAAATGGTTTTAATATGGTATTTGATGTTCAGTGTTCCATATCTCTCATTTTTCAATTTATAGAATTAAGTAATTCTGAATACTTTGAGCATATTTTGACCATTCTATTAAATAGTAATATTTTTGTGTTGATTCCCAGCACATTTTGTCTAAACTATTGCACATAAAATTATAACAGTTCTAGGTAGAAAAAGGAATGGACCATTTAAGACTTTTATTCATGTCCTTCATAACTGTCCTGTGAGGCTGCAACCGGGAATAGAATCGTATTTCAGCTGAATCCTATACACCATTGAGGTGGAAATGAAGGGGAGGAAGAGGGAAGTGGACACACGTGTTTCTCTCCAGCTCTTACATCCTGAGTCTTGGAAACACCAGTTGACCAACCGAGTCACACTGTGTCCTGCTTTTTTTTCATCCTGGGGCTCCAGGATCAGCACAGCCTTAAGTTTTTAACACATTCTCATGTTTCTCAGTCATTTTCTGCACATCACAAGGCGACTTATCAGGATTTGGGAATTAAATTCCTATGAGCACATGTTTGGTTGTACAAAATGGCCTTTTCAAGAAAGTATATGTAAAAAACAAAGACCAGGATTGAGGGAAAGAGAATCAATTATTGAAAAGAACAGATCTGAGGCCAGGCGTGATGGCTCATGCCTATAATCCCAGCACTTTGGGAGGCCAAGTCGGGCGGATCGCTTGAGTCCAGAAGTTCGACACCAGCCTGGGTAACATGGGGAAACCCAGTCTCCATAAAAAATACAAAAGATTAGCTGGGCATGGTGATGCACGCCTGTAGTTCCAGCTATTTAGGAGACTGAGGTGAGAGGATCGCTTGAACCCTGGAAGTGGAGGTTGCAGTAAGCTGAGATCATACCACTGCACTCCAGCCTGAGCAACAGAGTAAAACTCTGTCTCAAAAACAAAAGAGGAAAGAACAAATCCTTAGCTAAATAATTATTGAAAAGAACAGATAATTATTTAAATAATTATTGAAAAGAACAGATCCCTAGTTAAATAAAAATTAAAAAGAGATACATATTGAATACTGAAATGTGTTGCAAGCATCGATTAAATGTAAGCAGAAAAAGAACTAAAAGTCAGAAGCCTTTGTTTTCCATCCATTTCAGCTATTTGGAAGGTAGTCCATGCAGTGGTTGAGAGAGCATGTTGCGGTCTAGGCACCCCTCTCTTATTTTTCATTCACCTCAACCCAGCTTAAAAGACATATTTGAGGTTCATTTATTCAAATTCAAATAAACTTGTAGAAAAGTACATTGGCATAGTTGAAGCAATTTTACTTGTTCTGTTCTGTCACATCACGCAACAAGCGAAGGCTATAATTATAATTATGTTTTTACTTAAACTGTTGGGAGGCAGTATACTGCCCCCGAAGGTGTAAAGGTTCCTGTCTAGAAAGGCTTCATCACACACTGGCATGTTTTGCAAACCCAGAAGAAGCTAAAGTATAGCAAAGAGAGGCTTCAAACCCTGCTCAGCCAAATAAAGAGTAGGTACAGTGATTTCTTGAATAAAACATGGTATAGTCATTAGTTACAACCCTTAGAACAGTCATTAGGCCAGTCATGCCGTAAGACAAGCCCTCAGCTCCATCTGTGGCAAGGGGATTTGTTTGCCTGGACTTTTGGAAAATACTAGGATTCTAAATACACCCCAAATTCAAATTGTGTGGATGTTGCTTTCTTTTCCTGAATCAGATAATACAAGCTGATATAAAGCAGATAATAAAAACATGTCATACTTCAAAGGCCCTGTGAACCAACATCCTTTCACAATTTTTAGATGAGAATTTGAATGTATAAACTTTCCCTGCAAACATGTTCTAGGGATGACTCAGTTTCTTTTAAAATCTGCCTAAGGCTGGGCATGGCAGCTCAAGCCTGTAAATCCCAGTACTTTGAGAGGCCAAGGAGGAAGGATGGCTTGAGGCCAGGAATTCGAGACCAACCTGGACACCATAGTGAGACCCCCATCTCTACAAAATTTTTAAAAAATTAGCGAGATGTAGTGTCCTGTGCCTGTAGTCCTAGTTACTTGGGAGGCTGAGGCGAGAGGATTGCTGGAGCCCCAGAATTCAAGGTTGCAATGAGCTGTGATTGTGCCACTGCACTCCAGCTTAGGCAACAAAGCCAGACCTCATCTCTTAAAGAAAAAAAATCTTCATAAACAGCTCAATGTTAGTGAATTTTCACTGACTATATTAGAAGACACTGAAAATAATTCTCCCAAGAAATTCTCTGCAGAAACTTAGACAATTTCTGAAGCACCTTTAAATCCTCCTATTGACGGAGGCTTGGAGGGCATTGTGTTAGAGGGGCACGTGCTACTGGTTGGCTACTCTGAGGCAGACTCTGCACCCAGCAGTGAATATTTGTGTGGTTTTCTCCACAG
Seq C2 exon
GTCCCATGGGAAGATCTCCGTTATCTCTTTGGTGAGATCATGTATGGAGGCCACATCACAGATGACTGGGATCGCAAACTGTGTCGGGTGTATTTAGAAGAATTCATGAATCCATCTCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105877:ENST00000409508:75
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(8.9=100)
A:
NA
C2:
PF0302810=Dynein_heavy=FE(5.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development