HsaINT0049689 @ hg19
Intron Retention
Gene
ENSG00000158486 | DNAH3
Description
dynein, axonemal, heavy chain 3 [Source:HGNC Symbol;Acc:2949]
Coordinates
chr16:21078604-21080915:-
Coord C1 exon
chr16:21080736-21080915
Coord A exon
chr16:21078741-21080735
Coord C2 exon
chr16:21078604-21078740
Length
1995 bp
Sequences
Splice sites
5' ss Seq
GCGGTAAGT
5' ss Score
11.37
3' ss Seq
CTTTTTTTGATGGAACCCAGGTG
3' ss Score
5.09
Exon sequences
Seq C1 exon
AAATGGGAAGAAAAGCTAATTCGCATACAAGACAATTTGGATGCCTGGTTGAAATGCCAAGCCACCTGGCTGTACCTGGAACCAATCTTCAGTTCAGAGGACATCATAGCCCAGATGCCAGAAGAGGGGAGGAAATTTGGCATTGTTGATAGTTACTGGAAATCACTTATGTCCCAAGCG
Seq A exon
GTAAGTTTTTATACCCTAATAACTCTTACCAGCAGAAATACAAATGTTTCCTCATTATGCATTCTAGTCACCTTCCTTGAAACTTGTAAATGAACTAGAGTTTTGGAAAATCAATCTTTTTATATCTTCTTCTAATTTCAGAAGTTGTTATTATTAAAAATGCAAACATATGACCAGTGCGATGGCTCATGCCTATAATCCCATCACTTTGGGAGGCCAAGGCGGGGGTATCACTTGAGGTCAAGAGTTCCAGACCAGCCTGGCCAACATGGTGAAACACCGCATCTCTACTAAAAACACACACACACACACACACACAAATATTAGCCAGGCATTGTGGTGAATGCCTGTAATCCCAGCTACTCGGAGGGCTGAGGTGGGAGGATCGCTTGAACTCAGGAGGCGGCGGTTGCAGTGACCTGGGATCGTGCCACTGCACTCCAGGCTGGGAGAGAGAGCAAGACTCCGTCTCAAAAAAAATTAAAAAAAAAAAAAGCAAATACAAATATGTAACATAGAAAGCAGAAGCCTTTTGAAATCCCACTTCCCAAGCAGTAACTATAGGCAGTTTGTATTATTTAACTGTCATTTCTTACAAGGTTGTATTTGTTACAGGATAATGCAATAACAGTTTTATAGTGAATCCTTTTAGAATTCCAACAATTACCCACATTTGGTTACTCAGTTATTTAACAAATGTTTATTCAGTACCTACAATGACCCAGGTGTTATACTAGAAATCAGAAAATACTTGAAGGTGGCAAGAATATGATTTCTGTCTTCATAGAATTTGCTGCCTTGGCTGAGTGCGGTGGCTCACGCCTGTAATTCCAGCCCTCTGGGAGGCCAAGGCAGGCGGATTGCTTGAGTTCAGGAGTTGGAGACCAGCCTGGATAACATGGTGAAACCCCGTCTCTACTAAAAATATAAAAAATTAACTGGGTATGGTGGTGTGCACCTGTAATCCCGGCTATTCCAAGGCTGAGGCAGGAGGATCCCTTGAGCCTGGGAGGCAGAGGTTGCAGTGAGCCCAGATTGCGCCACTGCACTCTAGCCTGGGCAACAGAGCGAGACTCTGTCCCCCCCCCCACCCAAAAAAAAGTAATATACAAATAGTTATTAGAATGCAGAAGAGTGATTTAGTTGTCTCAGCGTGTCAAGGAAGGCCTCTAAAGCAGGAACGTTGGGATCAAGCCTTGAAGGATGGTAAGTTCACTGGGCGTGCAAGGCACCTAGAGGGATCTTTTATGAGGTCAAATCATTTTCCTTTCTTAAGTCAAGTGTGATCAAACTGGGGTGCACTTAAAAAGATTTTGCTGCAAAGCAATTTGTCTTCCCTGCTTTGTTTGTGGGAGTGAGATAAATGGAATTTAGATTGTCCAGCCAGCATAAGCCAATTCTTTATTAGTTAAGGTTGTTTGGGTGCAAGTGACAGAAACTGACTCAGGATAGCTGAAACGAGAAGACCAAATGGGTGTCTCATGGAACCCAAGGCCAAATAGCACAGCCAAGCCTCACAAAAGATGGATCTAGAACCCAGAAGCCTCTTCTCTTAGGAACTCCTTCCATCTCTCTGATCTTGGCTCCTCTTTCCTGGCCCTGCCTTAGTCAGTCTCTCTCTCTCTCTCTCTCTCTCTCCCTCCCCACCCCCCCCCCCAAGACTGGCTTTCTCTATCACTCCGTCACACAGAGAAACATAATTCTCACTCAGCCCAAACTAGTATAGAATGTCATGGTTTGGATTCTAAACTCCTTGGGTTAAAATATAATTGGGTTTGGTTGGTTTTAGTACCCAATCCCTGCCCAGTCAACCATGATCAGAGGAACAAGGTCATGTTCCATAAGCATTCACCCCTGTGCAGTTAGGAGGGGGATCAGGAGGCAGTTAGCTGGACAAGGAGTGCTGTCAGTTGATAGGTCACACATTCAATACAATGACCAATCTCAGAACTTGGGAACCTTATGATGAGTCTCACTTTTTTTGATGGAACCCAG
Seq C2 exon
GTGAAAGATAACAGGATTCTGGTGGCAGCCGACCAGCCACGGATGGCAGAGAAGCTTCAAGAAGCCAACTTTCTCTTGGAGGACATCCAGAAAGGGCTGAATGATTACTTGGAGAAGAAGAGACTATTCTTCCCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000158486-DNAH3:NM_017539:23
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF083938=DHC_N2=FE(14.4=100)
A:
NA
C2:
PF083938=DHC_N2=FE(11.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AATGGGAAGAAAAGCTAATTCGCA
R:
AAGAATAGTCTCTTCTTCTCCAAGT
Band lengths:
310-2305
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)