HsaINT0049689 @ hg38
Intron Retention
Gene
ENSG00000158486 | DNAH3
Description
dynein axonemal heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:2949]
Coordinates
chr16:21067283-21069594:-
Coord C1 exon
chr16:21069415-21069594
Coord A exon
chr16:21067420-21069414
Coord C2 exon
chr16:21067283-21067419
Length
1995 bp
Sequences
Splice sites
5' ss Seq
GCGGTAAGT
5' ss Score
11.37
3' ss Seq
CTTTTTTTGATGGAACCCAGGTG
3' ss Score
5.09
Exon sequences
Seq C1 exon
AAATGGGAAGAAAAGCTAATTCGCATACAAGACAATTTGGATGCCTGGTTGAAATGCCAAGCCACCTGGCTGTACCTGGAACCAATCTTCAGTTCAGAGGACATCATAGCCCAGATGCCAGAAGAGGGGAGGAAATTTGGCATTGTTGATAGTTACTGGAAATCACTTATGTCCCAAGCG
Seq A exon
GTAAGTTTTTATACCCTAATAACTCTTACCAGCAGAAATACAAATGTTTCCTCATTATGCATTCTAGTCACCTTCCTTGAAACTTGTAAATGAACTAGAGTTTTGGAAAATCAATCTTTTTATATCTTCTTCTAATTTCAGAAGTTGTTATTATTAAAAATGCAAACATATGACCAGTGCGATGGCTCATGCCTATAATCCCATCACTTTGGGAGGCCAAGGCGGGGGTATCACTTGAGGTCAAGAGTTCCAGACCAGCCTGGCCAACATGGTGAAACACCGCATCTCTACTAAAAACACACACACACACACACACACAAATATTAGCCAGGCATTGTGGTGAATGCCTGTAATCCCAGCTACTCGGAGGGCTGAGGTGGGAGGATCGCTTGAACTCAGGAGGCGGCGGTTGCAGTGACCTGGGATCGTGCCACTGCACTCCAGGCTGGGAGAGAGAGCAAGACTCCGTCTCAAAAAAAATTAAAAAAAAAAAAAGCAAATACAAATATGTAACATAGAAAGCAGAAGCCTTTTGAAATCCCACTTCCCAAGCAGTAACTATAGGCAGTTTGTATTATTTAACTGTCATTTCTTACAAGGTTGTATTTGTTACAGGATAATGCAATAACAGTTTTATAGTGAATCCTTTTAGAATTCCAACAATTACCCACATTTGGTTACTCAGTTATTTAACAAATGTTTATTCAGTACCTACAATGACCCAGGTGTTATACTAGAAATCAGAAAATACTTGAAGGTGGCAAGAATATGATTTCTGTCTTCATAGAATTTGCTGCCTTGGCTGAGTGCGGTGGCTCACGCCTGTAATTCCAGCCCTCTGGGAGGCCAAGGCAGGCGGATTGCTTGAGTTCAGGAGTTGGAGACCAGCCTGGATAACATGGTGAAACCCCGTCTCTACTAAAAATATAAAAAATTAACTGGGTATGGTGGTGTGCACCTGTAATCCCGGCTATTCCAAGGCTGAGGCAGGAGGATCCCTTGAGCCTGGGAGGCAGAGGTTGCAGTGAGCCCAGATTGCGCCACTGCACTCTAGCCTGGGCAACAGAGCGAGACTCTGTCCCCCCCCCCACCCAAAAAAAAGTAATATACAAATAGTTATTAGAATGCAGAAGAGTGATTTAGTTGTCTCAGCGTGTCAAGGAAGGCCTCTAAAGCAGGAACGTTGGGATCAAGCCTTGAAGGATGGTAAGTTCACTGGGCGTGCAAGGCACCTAGAGGGATCTTTTATGAGGTCAAATCATTTTCCTTTCTTAAGTCAAGTGTGATCAAACTGGGGTGCACTTAAAAAGATTTTGCTGCAAAGCAATTTGTCTTCCCTGCTTTGTTTGTGGGAGTGAGATAAATGGAATTTAGATTGTCCAGCCAGCATAAGCCAATTCTTTATTAGTTAAGGTTGTTTGGGTGCAAGTGACAGAAACTGACTCAGGATAGCTGAAACGAGAAGACCAAATGGGTGTCTCATGGAACCCAAGGCCAAATAGCACAGCCAAGCCTCACAAAAGATGGATCTAGAACCCAGAAGCCTCTTCTCTTAGGAACTCCTTCCATCTCTCTGATCTTGGCTCCTCTTTCCTGGCCCTGCCTTAGTCAGTCTCTCTCTCTCTCTCTCTCTCTCTCCCTCCCCACCCCCCCCCCCAAGACTGGCTTTCTCTATCACTCCGTCACACAGAGAAACATAATTCTCACTCAGCCCAAACTAGTATAGAATGTCATGGTTTGGATTCTAAACTCCTTGGGTTAAAATATAATTGGGTTTGGTTGGTTTTAGTACCCAATCCCTGCCCAGTCAACCATGATCAGAGGAACAAGGTCATGTTCCATAAGCATTCACCCCTGTGCAGTTAGGAGGGGGATCAGGAGGCAGTTAGCTGGACAAGGAGTGCTGTCAGTTGATAGGTCACACATTCAATACAATGACCAATCTCAGAACTTGGGAACCTTATGATGAGTCTCACTTTTTTTGATGGAACCCAG
Seq C2 exon
GTGAAAGATAACAGGATTCTGGTGGCAGCCGACCAGCCACGGATGGCAGAGAAGCTTCAAGAAGCCAACTTTCTCTTGGAGGACATCCAGAAAGGGCTGAATGATTACTTGGAGAAGAAGAGACTATTCTTCCCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000158486:ENST00000261383:23
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF083938=DHC_N2=FE(14.4=100)
A:
NA
C2:
PF083938=DHC_N2=FE(11.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AATGGGAAGAAAAGCTAATTCGCA
R:
AAGAATAGTCTCTTCTTCTCCAAGT
Band lengths:
310-2305
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development