HsaINT0052328 @ hg38
Intron Retention
Gene
ENSG00000171587 | DSCAM
Description
DS cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:3039]
Coordinates
chr21:40085602-40087287:-
Coord C1 exon
chr21:40087170-40087287
Coord A exon
chr21:40085766-40087169
Coord C2 exon
chr21:40085602-40085765
Length
1404 bp
Sequences
Splice sites
5' ss Seq
CAGGTAACC
5' ss Score
8.66
3' ss Seq
TTTTTCTTCCTGTGAGGCAGTAA
3' ss Score
0.5
Exon sequences
Seq C1 exon
CTCCTGCACGAATCCTGACCTTCAGTGGGACAGTGACTACTCCATGGATGAAAGACATTGTCTTGCCTTGTAAGGCTGTTGGGGACCCTTCTCCTGCAGTCAAATGGATGAAAGACAG
Seq A exon
GTAACCAGTAACCCAATGTATGCCTTCAGTGAGACTCTAAGAGATTACATCTGACATACTCAGGTTGTGTCTAGTGGTCTCCTAATTTTGTGTTTATTTATATTAGTGAAAACTCAAGGAAACCTACCAATTCTTCTGAGATGAGGGCAGAGAAGGAATCTCAGCTTTAGCACTGAAAGGGTCTGATTTATTGTATCAACCCTCTGTTAATTCAGAGCCTTCTAGTTCATGAGAGAATGCTTGCAAGGAAAGTAGTTGAACCAACTCAATTATTGTGGAAGTTTGCTGCACCCTCTCAGGTAAATTGTCCATGTAACTGAGATGAATGCAGCCAAGGCTATTGTGAGATTTAACACCTATCTCTTCTTCTTTAAAGATAGTGAACTAACCATAACTCAAATACCCTGAGAAAGAACTTTAAGAAATGGAGTACATTAGGACTTTGCTAATTTAAAATCTGGTTCTCCATACTCCATAGTAATTATTTAAATAATAGGAGCCAAGATAGAGGGAGAGAGTGAGTGAGATATGGTCTGTCCATATAACTTTTTAAAGTGCTATATCTCTATTCAGGAGAAGAAATTAGGATATAAGTTAAGGGTCGAAAATTCATTTATGAGCATAGAAATGTGATCTAATGGATTCAGAAGAATGCCTATTTTCAAGCAAAAGCACTTAGAAGGCATAAACTGTAGAAATAATGGCTTGGTGTAGTGACCAAACTGTAGAAATAATGGTTTGGTTTAGTGACCACTTTTCTCATACATTTAAAGTTGGTTCATCCAAATGAAATATGTAGCTCCCAAGGTCAAGTTGGCATTCTGCCTGTTGTGGGAATGACCCCAAAGGACTGGACAATCTGCCACCGGAGCAGTGGTTATGATGGCCACGCAGTTCTTTTTATACTAGGGTAAACTCATCACCCTCTTGAGATATCACATGTCATTTTTCATGTCAAAATCATGAATAATTGTGACTTTAAGTGAATCTAAAAATGATCCCAAGGTTTAGTTTCCCCTGTATGATTTGTTCAAACTGGCACTTCTGCCTACAGAAGAAATTCCCAGAATTGCCAAAATGAGGATATCTCCAGTGCCCACAGAGTGGAGTAAAGAGGGACCCATCAGTCTCTGGCACAGATGAGGAGTCCACTGACTTGAGCCAGAATCTGGGCCCTTGACACAGATCTCATCTTCAACGTAACATTTTTTACAAAGGAAAACTTCAGCTACACAGCTATTGATTGTTTTCATTATGTAATCATATTTAGTTCTTTCATAATGCAAGAAATATGAAGCTTCCAAATGTGTGGTTTGCTTCACAGAGTCTTTCTGTTTTTCCCCAACCTCAGCTAATTTGGATTGTAATTTCTTTAATCTGTGCATTTTTCTTCCTGTGAGGCAG
Seq C2 exon
TAACGGGACACCCAGTCTAGTAACGATTGATGGGCGGAGGAGCATCTTTAGCAACGGAAGCTTCATTATTCGCACGGTGAAAGCAGAAGACTCCGGCTATTACAGCTGCATTGCCAATAACAACTGGGGATCTGATGAAATTATTTTAAACTTACAAGTACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000171587:ENST00000400454:22
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.025 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0767911=I-set=PU(40.0=90.0)
A:
NA
C2:
PF0767911=I-set=PD(58.9=94.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCCTGCACGAATCCTGACCT
R:
ATAATTTCATCAGATCCCCAGTTGT
Band lengths:
262-1666
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development