HsaINT0054749 @ hg19
Intron Retention
Gene
ENSG00000181090 | EHMT1
Description
euchromatic histone-lysine N-methyltransferase 1 [Source:HGNC Symbol;Acc:24650]
Coordinates
chr9:140705913-140707625:+
Coord C1 exon
chr9:140705913-140706067
Coord A exon
chr9:140706068-140707457
Coord C2 exon
chr9:140707458-140707625
Length
1390 bp
Sequences
Splice sites
5' ss Seq
CGTGTGAGT
5' ss Score
7.42
3' ss Seq
CCTTACATTTTCCCTTTTAGCCT
3' ss Score
9.82
Exon sequences
Seq C1 exon
GAGGAGAACATTTGCCTGCACTGGGCGGCGTTCTCCGGCTGCGTGGACATAGCCGAGATCCTGCTGGCTGCCAAGTGCGACCTCCACGCCGTGAACATCCACGGAGACTCGCCACTGCACATTGCCGCCCGGGAGAACCGCTACGACTGTGTCGT
Seq A exon
GTGAGTGCAGTGCTTCCCCCAGCGCGGGCTGGCGCTGACCTGACCTGGGCGCCCAGAGAGACCGCTTGACAGTCTTGTGTTCACACTTGGGGCGTGAGTGGACACAGGCCCTCTGTTCCTTCGTGTGGAAGTCCATCCTTGGTGTTCCACACGCAGAGAAGTGTCTTTCCCAGTCCACGTTTGAGATCAGCTGTGGTTTATTTCTGGGTTAGGGAGGATTGTCATGAAAAAATTCCCAAGTTGGAGTCTCAGACCTGATACTCCTCACATGGCTGAGGGGCAGCATGGGAACAGCCCTGCTCCCAGCAGGGACCTGCCAGCTCAGAGTCCCCGAGAGGCTCAGGGTGCCTTCTGGGAGCAGTGCCACCCACAGCCAGGGCTGGAGTTGCTGGGGGCTGTGGCACTCGCCACTCAGGGCCCTTTTAAAACTTGAGACCTTCAGCTGGGTGGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCAGATCACCTGAGGTCAGGAGTTTGAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAATACAAAAATTAGCCGGCCATGGTGGCATGTGCCTGTAACCCCAGCTACTCCAGAGGCTGAGGCAGGCGAATCGCTTGAACCCAGGAGGCAAGAGATTGCAGTGAGTGGAGATTGCGACGCTACACTCCAACCTGGGCGACAGAGTGAGATTCTGTCTCAAAAAAAACCCAAAAAACAAAAAAAGCTTGAGACCTTGATCCCATAAAGTCATCCACACTCAGGTTGTTGTTGGTGGCCTGGGATGGAGTGTGTGTTTGGCTGCTGGGGAAGGACAGGGAACTGTGGGTGCTCCAGGCACCAGCCTCCAGTGACTCCCTGGCCCCTACACATGGGGCTGTGCCCTCCCACATGTGGATCTCACGGTGGCTCAGCCAGGTTGGTCATCTGGTTGTGTGAAGCCCAGCTCCACGTACGATGACTGCAGTCTGGATGCAGTGAGCAGGAGTGGAACTGAGGACTGCTCACGCTGTGCGTGGCCCAAGCTTGGCCTCTCTCCCTCCTTGCTTCCCTTCTTATCCTTGAGGGTAAATTTGAATGAAAAATCCAAGAAAAATCAAATGCCGCCCTGGATTTTACACTCTTCCTGCTAAGAAAACAGCCTGCTGACTTTGACAGTGAATGTGGGAGAGGAGGAAGGGAATCATGTTCCTGGGTGAGCTAAAGCCCGTCTTTGCAGAGTCATTGCTGAGCAGACTTGTTCAAGTTATCTCACAGTGAATAGTGTTCCCTTTATTGTTAGTGATGACGGACATTTTATAAATCTCATCTGTATCACATTTTCAAGTCAGCTTTAAATGTTTTGTGGCCTTACATTTTCCCTTTTAG
Seq C2 exon
CCTCTTTCTTTCTCGGGATTCAGATGTCACCTTAAAGAACAAGGAAGGAGAGACGCCCCTGCAGTGTGCGAGCCTCAACTCTCAGGTGTGGAGCGCTCTGCAGATGAGCAAGGCTCTGCAGGACTCGGCCCCCGACAGGCCCAGCCCCGTGGAGAGGATAGTGAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000181090-EHMT1:NM_024757:19
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.105
Domain overlap (PFAM):
C1:
PF127962=Ank_2=PU(51.7=88.5)
A:
NA
C2:
PF127962=Ank_2=PD(47.2=73.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAACATTTGCCTGCACTGGG
R:
TGCTCACTATCCTCTCCACGG
Band lengths:
318-1708
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)