HsaINT0059103 @ hg19
Intron Retention
Gene
ENSG00000088926 | F11
Description
coagulation factor XI [Source:HGNC Symbol;Acc:3529]
Coordinates
chr4:187188290-187192925:+
Coord C1 exon
chr4:187188290-187188345
Coord A exon
chr4:187188346-187192762
Coord C2 exon
chr4:187192763-187192925
Length
4417 bp
Sequences
Splice sites
5' ss Seq
GTGGTAAGT
5' ss Score
10.36
3' ss Seq
TGCCATGTACTACATCACAGAAT
3' ss Score
4.37
Exon sequences
Seq C1 exon
GATGATTTTCTTATATCAAGTGGTACATTTCATTTTATTTACTTCAGTTTCTGGTG
Seq A exon
GTAAGTAGAGTGTTATCTTAACTATGGGCTGGGAGAGGGAAATCACACTGCAATCTCCACACATGTGGGAGAATCCCACACCATTTATGCCGGGAAGGAAATAAAATGTTTTTATTAACTTCCTGCCTGAGGCTCCAGAGGTTTTCAAAGCAGGGTAGGAATTGAGGTGAAAAAATTGTTTGTACTGGTAGGAATCTGTGTCTATATGTGTACCATATCTACATCCATGCCTACATACATCATTCATTTAAATGATATTTAAAAGCAATATTAAAAAGAAGAAATCTTGATTTGCCTCACTAATTAGTTGGTTTTTCATAAAGCAGTCAGTTCAATGGAACATACACACACACATAAAATAGGAATTTTGTACTGAAAAATGTTATGTAACTATTCATACACAGTTTATGCATTTCAATAATTTAACTACCCTGTTAATTCTCCACCCTATGTCACATCTGCTAAATTTGTTTATAAATTACTTAGCCAATATTAAGTAGGATATATCAGTACAGGTATTGTTTAGTTCCATGACCATTCTTTATTTAAAATGAAAGCTGAAGCATTCCTTTAGAAAAATAGCTTATGTCTACATGTTATATTTAATTTCTGATACTATTGCTAGCATTTTAAGCATAGTAAATTCTTTTTGCTGGCCTATGTGAAAAAAGGCAAACCTAGGTGAAGATATTAAAAGTAAATTCCACTTAATATATTAAATTACACAGCTCATAATTTCAATTTTCTCTGTGACAAGACTACTGCTCAGGTTATAATATTCCTTTGTTATAATTATCTGGAAATTGTATTGTTATTTCATTGATAAATATGTCAGCGCTAAATAATTTGATATATTTTGAACACTGGACCCAATAACTACATAAACAATTGACCCTGAATCAGGGGTTCCACATCCATGGATTTAAACAACATTGAAGTGAAATTTTTTAAAAAAAATTATATCTGCACTCAACATGTGCAGAGTTTTTTCTTGTCATTATTCCCGAAACAACACAGTATAACAACAATTTGCATAGTATTTACATTGTACTAGGTATTATAAGTAATCTAGAGATGATTTAAAGTACACAGGAGGCTGTGAGTAGGTTATATGTAAATACTATGCCATTTTCTATCAGGGACTTGAGCGTTCATGGATTTTGGTATCTGCAGGAGGTCTGGCAGCCAATCCCTCATAGATATCAAGGAATGATAGTGTACATATTTAGGTCCTTTATACATGCACATGGAACATTTACAAATATTGACCACACACAAGCCTCTGAAACAAGGCTCAACAAATTTTAAGGGGTTAAAATTATACTGATCATGTTATTCAATCACCGTGAATGGGAGCTAGAATAATAATAAAAAGGGAATTGAAAATCTGCAAACGTTTGAAAATTGAGTATTTATAATCACCGTGAATGGGAGCTAGAATAATAATAAAAAGGGAATTGAAAATCTGCAAATGTTTGAAAATTGAGTATTTATACCTTTTTAGATTAAGATGAATCAGAGATGAAATCACAATGGTAATTAGAAAAGGAATTGTACAATAATGAAAGTACAGTATATCAAAACTTTGAGATGTAACCGAATCAGTGTTGAGATCAAATGTATAGATTTACATGTATACATTAGAATACAGAAAAGGGAAAAATTAATGATATAAGATGACAAGAAGATAGAGAATAGCAACTTAAGTGCTAAGAAATTAGAAGGCAGAAAGAAGAAATCGCAGAAATTAATTAAATGGAAGACACACATATTTGAGAGGTCAACATAACCCCTTTCTAGCCCATTTTATAAGGTCAGGGTAATCTTGACACCAAAATCTGATAGGAAAATTCTGAGGAAAAAAAGTCACAGGTCTTTTATCTTATGAACATATGTACAAATGTCCTAAACAAAATATTATCCAACTTAACCCAGTAGATTGTTAAAAAAATTAAAGGATGATTACATTGTGATATTGTGACAAAGTTGGGTTTATTCCAGGAATGAAAAGTTGATTTAACATTCAAAAATCAATAGATGTGTGACTTCGGGGTACATACCGAAAAAAAAGAAGGGAAAGCAGGAACTCACACAGATATACTTGTACACCCATCTCATAGCAGCATTATTCACACTAACCCAAAGGTGGAAGCAGCCCATGTGTTTATCAACAGGTGACTGGATAAAGTGTGGTACATACATACAAAGGAATATTACTCAACCCTAAAAAGAAAGGAAATTCTGACACATGCTATGACATGGATGAACCTTGAGGACATTACGCTAAGTGAAATAAGCCAGTCACAAAAGAACAAATACTGTGGGATCTCACTGATAGGAGGTACTTAGGGTAGTCAATTTCATCAAGACGGAAATTAGAACAGAGGTTGCCAGGGGCCGAGGGGCCAGGGGAAGGGCTGAGGGTTGGTGTTTAATGGGCACAGAGCATCAGCTGGCGAAGTTGAAAAGTTCTGGAGGTGGATGGTGCTGATGGTTGCACAGCAATGTAAATACCCTTAGTGCCACAGAACTGTACACTCAAGATGGCTACATGGCACATGGTATGCTATCTGTCATAATAAAAAATAAAAATAATTTTAAATGTTAATATGTGCCGAAAAATGCTTGCTAAAATTCTATTAATGATCAAAACTTTAAATAAACTGGAAATGGAAGAGAACTTTCATCAGCTATTAAACGATATTTTAAACAAAAGCAAACAAAAATCCAAACCAAAAATCTTCAAGAAACATAATACGTAATAGCGGAATATTGAAAGCTTTCCCAAGGGATTGAGAATAGGACAAGAATACTTCCCATTATTTCCATTTACTCTTGACTGGAGGTACTCGTTGGTGCGGTAAGGAAGGGAAATAAAAGGAAAACGATTAGGAGGAACATAAGCTCTCGTTTTTCACAGATGATGTGATTGAGTACCTAGAAAAATCCAAAATTAACCATCACATAAATTATTTGAGCCAATTAATTAAATGAGTAAGAAGTCTCGATACAACGTCAATATACAACAGCAAGCACTTGCTCGTTCGCAAAAGCAGATGAACTAGTTTTTACTGACACTAGAAGCAGCATGTGTTCCATGTGTTCCACATCCATGCACTCAAACAACCTTGACGTGAAATATTTTTTAAAAAATTGTATCTGTACTCAACGTGTGCAGAGTTTTTTTCCAAAATTGTTTTCCAAAAATTTTTAAATGTTTATATGTTTAGGGGGTGTAAGTGCAGATTTCTTACATACATATATTATGCGGCGGTGAAGTGCCGGCTTTTGGTGTACCCATCACCCAAGTAGTGAACACAGCCTCCAACAGGTAATTTTTCAACGCTCACCCCACTCCCATCCTCCCATCTAGTGGCATATTGAAAATCAATTTGTCTTGTAAAATTAAATAATCCAATTAGGAGGGGGATATATTCTAAGGAAATTAGTGCATGATGCACACACACACACACACACAGAACACGTGTGTGCGCATGTGCACATGAGAGAGAGTGAGAGAGAAACTGGGTCTTGCTCTGTCGCCCAGGCTGGATTGCAGTGGTAAAATCACAGCTCACTGCAGCCTCAAACTCCCAGGCTCAGGAGATCCTCCTACCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGGAAACAACCATGCCCAGCTAGTATTTTTTTTTTTTTTTGTATTTTTTATAGAGACAGGGTCTTGCCATGTTGCCCAGGCTGGTCTTGAACTCCTCAGCTCAAGCAATCTACCTACCTTAGCCTCCCAAAGTGCTGGGATTACACGCATGAGCCACTGCGCCCACTCCGCATTATTAAATATAGAACATTTATTTGATTCATCAGTTAATATTCTTCTTAAAAGTACTATTTTAATGTAGCAAGATTGCTTTCCACCAAAAGGTGGGGTTTCCACGGTGGGGTTTCCAAATTATTCTCAATGGGGTGAGGATGTGTGTTATCACACCCCCGAGCCATCAGATGCTGTCAGAAAGTGATCACTCTGAAGTCTTTGTTTCAAATAAGCACAGGGTTTGGATAAAGAGACGCAATTAGGAAAGGAAAAAGCAGAAGGCTCGTTCCAGACCTGGATGAGATCCTAAAAAGCAGCAGCTTTTGCCAGTAAAGATCCTTGAAATGATTCAATTACCCTCAAAGCACTCCTTGTCTCCAAGACAATCACTCATAAGCACAATTCCATTGAAGCCAACGTACCATTTTGTGATTTTCGTTTCCACCTGAGGCTGTTCATTCAATAAACTCACATAAAAGTGTTTATTGCCTTGATTTCCAAATTCAGGCGTATTTCCTGGTAAGTAGAGCTACTTGCCTTGCCTTTATGAGATTACCACCTAACTAGATGTATGCCCAGTAAAATCCAACATAACGCATGCCATGTACTACATCACAG
Seq C2 exon
AATGTGTGACTCAGTTGTTGAAGGACACCTGCTTTGAAGGAGGGGACATTACTACGGTCTTCACACCAAGCGCCAAGTACTGCCAGGTAGTCTGCACTTACCACCCAAGATGTTTACTCTTCACTTTCACGGCGGAATCACCATCTGAGGATCCCACCCGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000088926-F11:NM_000128:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0002421=PAN_1=PU(63.1=96.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)