HsaINT0071947 @ hg19
Intron Retention
Gene
ENSG00000121957 | GPSM2
Description
G-protein signaling modulator 2 [Source:HGNC Symbol;Acc:29501]
Coordinates
chr1:109441501-109444567:+
Coord C1 exon
chr1:109441501-109441616
Coord A exon
chr1:109441617-109444411
Coord C2 exon
chr1:109444412-109444567
Length
2795 bp
Sequences
Splice sites
5' ss Seq
CAAGTTAGT
5' ss Score
4.22
3' ss Seq
GAATTAATTTCTTCTTGTAGGAA
3' ss Score
8.99
Exon sequences
Seq C1 exon
CGTCTCCTTATTGCAAAAGAATTTGGAGATAAAGCAGCTGAAAGAAGAGCATATAGCAACCTTGGAAATGCATATATATTTCTTGGTGAATTTGAAACTGCCTCGGAATACTACAA
Seq A exon
GTTAGTCTAATATTTCTGTAGATAAATGTAAAATGAATACTCAGTCCCATTAATTCATAGGCTTTAGGTTTAAAATCTGATTGTAGCAGAACTTTTGGCATCTAAGCCTCAATTTCCTTATCTGTAACAGAATATATCAATACTTCATTTTGGGGAATGCTGTGAGGATTGAATGAAATAATATACTAAACACAGTATCTGGTACACAGTGCTCAATAAATATTATTGTACATAAGATTTAATAGCAGCAGTATGACCCCTTTATAATATTGGTTTTTATCTTTAAAAGTAATTGTTTTTAAATGAAGTTTTCAACCTTTAATATCTTTTAAACCTGTTTAGCATATGTGGTGTATATTGTGTATATGCTTTATTTCACTCAGTTATGGGTTAGAAGAGAGGCCAAAAGAAAGCCTTGTAACAAAAATATTTATAGTCTATACCAGTGATCACTGAATTTTTTTCTCTACCTTCCCACCCTCTTATTGAGCAGTTCTCCCTTTACCCTCTTTCTGCCTATATTTGACTGTCACTGTAAGCTGAGTCCCCCATTCACTTACCTGAAGCATTTACAATCCCAGCTTCTTCTGTGGCAGGATCTCTCTTATCAGTAGATTTGAGACATAGATGATAGAAAGTTTAGACAGCTTCAAGTTGCCTGATCTGTGCTTTCTAGATTGAGTTTTCCCTAGTTAGTGGGGATTGAAGCCTCTTACAGATTTTGGGTAGAAGGCAGTTTGACTAAACCGAAGACACAGTGATTGATTTGTATTTTGTTAAAGAAGCCAATATGAGACAGTTCTGGATAATTTGTCATCTTCATAAAAAAGGTAAAATTGTTTTAGGCCTATCTAAAAAAATTAAATAGCATTCCACTTTGCTTTAAACATCAACTAATGGTTAATATTTGTTGGTTAGGTTAGTTAGATATGAAATAGCCTCCCAAATAAAATATATCACTGTGTACTATGTGAAGGAGTATATATTTTGATTTTAAATATAAAAATTTCCTATATTTAAAGCCAAGGGATATAGAGAAGTCTTAATTATTAAATGGTGTATCTGTGTTAAATACTGAAAGGTTCTATTATAAAATGGATAGTGGCTATTTGACTAAAGAAGCATGAATATAAAGTAATGAAACTTAGTTTTTTTCCTCCCAATAAGCAGGCTAGAACTCAGAACTTTATATATATTCCAAGTCGTTGGTTAGAAATATTTTTAGAACTCTTCTTTAGATTTTTTTTTTTTTTTTTTTTTTAAATACGGAGTTTTGCTCTTGTCGCCCAGGCTGGAGTGCAATGGCACAATCTTGGTGCACTGCAACCTCGGCCTCCCCGGTTCAAGCGATTCTCCTGCCTCAGCTTCTGAGCAGCTGGGATTACAGGTGTCTGCCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCGCCATGTTGGCCAGGCTAGTCTGGGACTCCTGACCTCAAGTGATCCGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAACCACCACACCCAGCCTGGAATTGTTATCAGGGCCAAACAAGAAGGCTAACAATGTAGATCCATATCCTTCCGGATACAAAGCAGTAGTTTGGTAAACCTATGTTAGTAATTGAATTTGGTTCCAGAAAGATTTCTGATCATTTACAAATCAACTGTACCATCAAAGAATAATGGTATGCCAGAAAGCATTATGCCACAGGATCTGAAAGCAATTCCAAAAGTCTTTCAAAAATATTTGAAAAGACAGGCAACATTAGAATAAGTAGGTAGCCTCCCAAGGTGACAGATTTGAAGGTATCATCATTAAATATGTAACTTTAGATTTGTTTGCTTAAAAAAAGCTATCACGTTACCGCATAGTAATTTGTCATATAGTTATAAGTGATATGAAGTAATTATACTATTTGACAGAAATAATGGGAGGGTCATTTAAATTACTGAATCCAAAAGCATCTATAGGTTTAAGCACTGATAATAACACATTAACATTTATACAGCAACTACTATGCACAAGATGCTATTCTAAGCACTTTATACATATTAATTTAATCCTCACAAAAATCCTTCGAGATATTTCCCCCATTTTATATAAGAAGAGACTGGTATACAGAGAGATTGAGTGACTTTGCCCTTAGCTTAGTAATTGGCAAAGTTGGGATTTAAACCCAGTCTAGCTCCAAGATCTATGCTCTTAACTGCTACGCTAGCTTCTCACTGGCAATACCACAGGTAGAATTTGGGTAATGTTTGGATGTAGTATTCAGTATTTTTCATGAGTTGGTGACTAATGCCCGATACATAAGAATTTTACCTAAGTGGTGACTAATAGCCTACACATAAGAATTTTACCTAAATATTTTAAATTTTGACAATGCAAAGGTGACGGTATGATTGAAAACAGATGTCATGTGGAAAAAAGCCTCTTTTAGCTATTGCCAATACTAAAGGGAAAGTTTTTTTAAATGTTAAAGATATTATGTTAATCTCTAGAACCTCTTGATTTTATGTTTCAATACTCCTTTACTTTGATGAATTGTTAGGATTCTCAAATTTATTCTAAAAGTCTTGAATCTTCTTTCTGTGTTTCAAAAACGTCTTTTCATTTTGTCTAAAAGTAATGGAGAAAGTACGGGATATGAATATTAGGCTCTCAGAGATTTAAAGACAGCAGAAAGCAGCAGAGAGGAAAAATGAGAGTTTTGTTTTGTGATTCTTAAAGCCCAAACTGAGAATGATCATTATATAAGAATTAATTTCTTCTTGTAG
Seq C2 exon
GAAGACACTACTGTTGGCCCGACAGCTTAAAGACCGAGCTGTAGAAGCACAGTCTTGTTACAGTCTTGGAAATACATATACTTTACTTCAAGACTATGAAAAGGCCATTGATTATCATCTGAAGCACTTAGCAATTGCTCAAGAGCTGAATGATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000121957-GPSM2:NM_013296:7
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF134241=TPR_12=PD(10.0=15.4),PF134241=TPR_12=PU(37.2=74.4)
A:
NA
C2:
PF134241=TPR_12=PD(61.5=90.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)