HsaINT0075915 @ hg38
Intron Retention
Gene
ENSG00000109758 | HGFAC
Description
HGF activator [Source:HGNC Symbol;Acc:HGNC:4894]
Coordinates
chr4:3444311-3444733:+
Coord C1 exon
chr4:3444311-3444442
Coord A exon
chr4:3444443-3444622
Coord C2 exon
chr4:3444623-3444733
Length
180 bp
Sequences
Splice sites
5' ss Seq
CAGGTGCGC
5' ss Score
9.1
3' ss Seq
CTCCTCGGCCCTGCCCCCAGCTT
3' ss Score
7.3
Exon sequences
Seq C1 exon
AGAAATGCTTTGATGAGACCCGCTACGAGTACCTGGAGGGGGGCGACCGCTGGGCCCGCGTGCGCCAGGGCCACGTGGAACAGTGCGAGTGCTTCGGGGGCCGGACCTGGTGCGAAGGCACCCGACATACAG
Seq A exon
GTGCGCCACGGGGTGTGAGCCGTGCCACTGACCCCTGACGGGTGTCCCTGTCCACACCCGAGTGGGAGGAATGGCCTGAGGTCACCCAGAAACAAGGGACAAGGGGTGGACCCCGGCCCCGACTCCGCTGTCGTGGGGCACTGCGCGGCCCCTGGCCCAGCTCCTCGGCCCTGCCCCCAG
Seq C2 exon
CTTGTCTGAGCAGCCCTTGCCTGAACGGGGGCACCTGCCACCTGATCGTGGCCACCGGGACCACCGTGTGTGCCTGCCCACCAGGCTTCGCTGGACGGCTCTGCAACATCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109758:ENST00000382774:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0003913=fn1=WD(100=80.0)
A:
NA
C2:
PF0000822=EGF=WD(100=86.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAATGCTTTGATGAGACCCGC
R:
CGATGTTGCAGAGCCGTCC
Band lengths:
242-422
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development