HsaINT0076373 @ hg38
Intron Retention
Gene
ENSG00000159399 | HK2
Description
hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923]
Coordinates
chr2:74881711-74882239:+
Coord C1 exon
chr2:74881711-74881859
Coord A exon
chr2:74881860-74882119
Coord C2 exon
chr2:74882120-74882239
Length
260 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGC
5' ss Score
8.7
3' ss Seq
GTCCTAACTTCTCCCTGCAGCTC
3' ss Score
10.45
Exon sequences
Seq C1 exon
AGAAAGGGGACTTCTTGGCCTTGGACCTTGGAGGAACAAATTTCCGGGTCCTGCTGGTCCGTGTTCGGAATGGGAAGTGGGGTGGAGTGGAGATGCACAACAAGATCTACGCCATCCCGCAGGAGGTCATGCACGGCACCGGGGACGAG
Seq A exon
GTGAGCAGGGCGGCGCCTTCAGGAGGGGGCCCCTGGTGGACGTCACCTCTTGCCTTCGAGGACAGTGCTTTCTCTGCTCATCTGTGACCCTGGGGAGGGCTAGCTGGACCCAGGGCTGCAGCCTGGTCTTGACTCAGGTTTGTGCCTGAGCCTGCATTTCTTCTGGGTGGAAAGAAACATTGATGTTGTGCGCAGGCCCTACTGGGGGCAGCCTGCCCTGCCCAGGGCCCCTCCCTCAGTGTCCTAACTTCTCCCTGCAG
Seq C2 exon
CTCTTTGACCACATTGTCCAGTGCATCGCGGACTTCCTCGAGTACATGGGCATGAAGGGCGTGTCCCTGCCTCTGGGTTTTACCTTCTCCTTCCCCTGCCAGCAGAACAGCCTGGACGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000159399:ENST00000290573:11
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0034916=Hexokinase_1=FE(23.8=100)
A:
NA
C2:
PF0034916=Hexokinase_1=FE(18.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTTCTTGGCCTTGGACCTTG
R:
CTCGTCCAGGCTGTTCTGCT
Band lengths:
260-520
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development