HsaINT0077905 @ hg38
Intron Retention
Gene
ENSG00000187522 | HSPA14
Description
heat shock protein family A (Hsp70) member 14 [Source:HGNC Symbol;Acc:HGNC:29526]
Coordinates
chr10:14854125-14855943:+
Coord C1 exon
chr10:14854125-14854280
Coord A exon
chr10:14854281-14855840
Coord C2 exon
chr10:14855841-14855943
Length
1560 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAAA
5' ss Score
8.59
3' ss Seq
GTGTGTGTATGTGTGTACAGAGC
3' ss Score
6.62
Exon sequences
Seq C1 exon
ATCCTTCAAACATGATGTGAGAGGAAATGCGCGAGCCATGATGAAATTAACGAACAGTGCTGAAGTAGCGAAACATTCTTTGTCAACCTTGGGAAGTGCCAACTGTTTTCTTGACTCATTATATGAAGGTCAAGATTTTGATTGCAATGTGTCCAG
Seq A exon
GTAAAACTGAAGTTCAAAAAACTTTTTTAAAAAATTCCAAGAACATGTTTGTTTAGGTATAATTTTCTTACTTTGGGTTTTTTGTTTGTTTGTTTGAGATTTATCAACCATCTATAATGTCTTCACTTTATTGGGGTCCAGTTTTTGTCAGACTAAATAGCTGTTACCAGAGTAATTACATAAGTTGTGATTGCTTGCCCTGTTATTTTATGGCTACAATTAGGAGTGTGCAAAGGCATCCTAGAACCTTCAACCTAGATCCTACAAGTGATAAAGTACAAAGGGAGGACGTGCTGTAGTCTTTGTGTTGCATATTTGCTAATAATAATGATACGGCCTATTCAAACCTCTCAACAACATAATAGGTGACTTTGAAGCATAGTGAAAATTTCCAAGACTGCAGTATATATTTTTTTAGGATTCTAGTGACTGTATTTGGTTAAATTCTCTTTTCATCTGTTTAGTTTAGCTTCTTCACTTTCCCCGGGCCTTCATGAAGACTCTAGATCTGCACTGCCCAATAAAAGAGCCACTAGCCACCTGTGGCTGCTTAAATTTAACTTAATTAGGATAACATTAAAAATGCAGTTCCTCAGTAGCACTAGCTGCAGTTCAAATGTTCAGTAGTCATGTGGCTAGTGACTGGTAGAAAGTCCTGTTGGACAGCTATGCTCCAGATCTTTGAAGAAAGAGTTCAGGCTACAACTCAAAAGATAGAAAAGGCATTGCATTGAATTAGAATCTCTTTTTGGACAGAGTATGTGTATTTTTCTAGTTCCAGAATTCCTTAGGGTTAAGTTTGTCCAAGTCCTCGGTATATATTTGCTTTATTAATCAGTAATTAAGAAGGAAATGAAATTTATAATTTTTCATTAGGGAAATTTTGCCTTTGTCACAAAGATTTCAACCATAAAAGTATGCTTTAATATCTATAAGGTTTATAGATATTAATAGATAACATTATTTTTTAAGCCACTCATCTGCATTTAAGAAGTTCTGTATGAAGATTAGGGAGTACATTTTTCATGACCATAAATTTTTCTTAAAACTTTGTTATCTGCCAGCATTCAATTTCTCAGGGAGTACGGAGGGGCTAAACTTATGTCCAACATGGTCTCAAACTGTCAAGGAAAATTATTAGAAATAATGTTTAAAACTTTAACATATAAAAATGGCAGAAACTTTCAAATGATGGTTTGATTAGGGTCAGTAGGTTTATTGTTGGGAATGCTATATGGGTATGTGTTTTTAGATTTGTTATTTTTTGGAAGCTTATAAGTAGACCATAAGCAAGATGGGCTTTCACTTGAATTTGATATTATCTTCATATATATGTAGGTGAATGACCTAGACTCTCCTGTCTCCATGATATTGCATCACTCTTACTTAATACCTTATTCTTATGGTAAACCTGTCATTCAGAGAACTATCATATTAAGTTTTGGCATTACTCTTCACAAGAAAAAGAAAAGTGATATTTGTTTGATTGTACTGAGCCCCGTTTTATCTTTCTCTTGTCCCTGTGTCTGTGTGTTTCTGTGTGTGTGTATGTGTGTACAG
Seq C2 exon
AGCAAGATTTGAACTTCTTTGTTCTCCACTTTTTAATAAGTGTATAGAAGCAATCAGAGGACTCTTAGATCAAAATGGATTTACAGCAGATGATATCAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000187522:ENST00000378372:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0001215=HSP70=FE(10.3=100)
A:
NA
C2:
PF0001215=HSP70=FE(10.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCTTCAAACATGATGTGAGAGGA
R:
TGTTGATATCATCTGCTGTAAATCCA
Band lengths:
256-1816
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development