HsaINT0082839 @ hg38
Intron Retention
Gene
ENSG00000160255 | ITGB2
Description
integrin subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:6155]
Coordinates
chr21:44901492-44903535:-
Coord C1 exon
chr21:44903365-44903535
Coord A exon
chr21:44901734-44903364
Coord C2 exon
chr21:44901492-44901733
Length
1631 bp
Sequences
Splice sites
5' ss Seq
TTGGTGAGG
5' ss Score
6.9
3' ss Seq
CCCCTCCATGTGCCCTGCAGGCT
3' ss Score
8.87
Exon sequences
Seq C1 exon
GCCAGGCAGCAGCGTTCAACGTGACCTTCCGGCGGGCCAAGGGCTACCCCATCGACCTGTACTATCTGATGGACCTCTCCTACTCCATGCTTGATGACCTCAGGAATGTCAAGAAGCTAGGTGGCGACCTGCTCCGGGCCCTCAACGAGATCACCGAGTCCGGCCGCATTG
Seq A exon
GTGAGGCCCAGGCACTGCAGGACAAAACCCAGTCCTTTCCCAGACCCTGGCCACTCCTGCCTGTGGCCCACACAACTCCTCGCACTCAGGTCCCCAGGGTAGATCTGGGGGCCCCAGATGCAGGTCCCCCCAGGGCATCCACAGGGCTGCAGTCGGCCTGCCTCCCTGCCAGGGGCCACACCCAGTCCCTGGCTCCCCAACACTTGTAGACATTGTCCAGCCCTCCACTTCCCCTTCCATCTTCTACTTCCTTTATTTATTTCTTGGTATGTTTAAAAGACAAAATTCTGACAGTGCCAATTATTAAACATTAAAGACCACAACACATATAGACGGCACAGCGACGGCAGCACTGAAGAAACCACACAGCAAGCTCTGCTGGGCCAAGGGCTCCGCTCTACACCAGCACTGCCTTGCCACAGAGCAGGTCTCCAGCACACGTGTGTGTCAGTCACAGCGCATGTCTTCCCCGCCGGCCGTGGCTTCTCACATCGGCACTCTGCCACCTTCCCTACATGCGGGGATGCACACATGCACGATAACACACACACACACAAGCAAATGCATGCTCACACAAATGCACGCTCACACACAAATGCACGCTCATGCACGTGAATGCACGCTCACACACAAATGCATGTTCACACATGCAATGCACACTCACACACAAATGCATGCTCAAACGCAAATGCACGCTCACACATGCGAATGCACACTCACACATGAATGTATCCTCACATGCACAAATGGATGCTCACACACGCGAATGCATGCTCACACACAAAAGCACACCCAAACTCAAATGCACACACACGTGAATGCATGCTCACACACGTGAATGTATGCTCACACACATGCTCAAACACACAAATGCATGCTCTCACATGTGAATGTATGCTCACACATGAATGTATGCTCACACGCAAATGCATGCTCACACACGCGAATGTATGCTCACATGCACAAATGCACGCTCACACACGTGAATGCACGCTCACACACAAATGCATGCTCACACACATGAATGCATGCTCACACTTGCATGTGCACACACATGCACACACAGTCATACACACGTGCAAGACCACATGTGCACACAGACATGCTCACATGCACACTCATGATCACCCATGTATGTCTTCACTCACATGTATAAATCGTACATAAACACACATGCCCACATATGTACCTGGTCACCTACGTGAACTAGGTGTGTCCATACCTGAACATGCTCACATGCATACAGGAATACGTGCACACACAGTTGTGCTACGCATGTACACACTCATGTTTACACATGCAGATGGCTGCACACACAGATACACATACGCACCTGTTCACATGCCCACATGTATACCTGGTCACACACATACATGCAGGAACACACATGCATACACTTATGCTCATCCATGTACATTGCACACTCCCAGGTTCACACACACGCCCACATACGTTCACATGTGTGCTTGCACAACGCACATGCTCACACACACACTCCACATGTGCCATCTTGCTTTCTCCACCTCCCTGCTAGGAGAGAGGAAACAGGCTTGCCCTCGTGCCCCTTTGAAGCTGGCCCTCCCACCTGGGCCCAGCCTGCCACCTCCCCAGCCCCTCCATGTGCCCTGCAG
Seq C2 exon
GCTTCGGGTCCTTCGTGGACAAGACCGTGCTGCCGTTCGTGAACACGCACCCTGATAAGCTGCGAAACCCATGCCCCAACAAGGAGAAAGAGTGCCAGCCCCCGTTTGCCTTCAGGCACGTGCTGAAGCTGACCAACAACTCCAACCAGTTTCAGACCGAGGTCGGGAAGCAGCTGATTTCCGGAAACCTGGATGCACCCGAGGGTGGGCTGGACGCCATGATGCAGGTCGCCGCCTGCCCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160255:ENST00000355153:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.022 A=NA C2=0.118
Domain overlap (PFAM):
C1:
PF0036213=Integrin_beta=PD(41.5=96.6)
A:
NA
C2:
PF0036213=Integrin_beta=PD(0.1=0.0),PF0036213=Integrin_beta=FE(27.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCGTTCAACGTGACCTTCC
R:
TTCCGGAAATCAGCTGCTTCC
Band lengths:
348-1979
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development