HsaINT0084331 @ hg38
Intron Retention
Gene
ENSG00000089558 | KCNH4
Description
potassium voltage-gated channel subfamily H member 4 [Source:HGNC Symbol;Acc:HGNC:6253]
Coordinates
chr17:42178793-42181278:-
Coord C1 exon
chr17:42180870-42181278
Coord A exon
chr17:42179027-42180869
Coord C2 exon
chr17:42178793-42179026
Length
1843 bp
Sequences
Splice sites
5' ss Seq
CGCGTGAGT
5' ss Score
8.4
3' ss Seq
TTGACCTCTTCTTCCCACAGACA
3' ss Score
11.83
Exon sequences
Seq C1 exon
GTGGGCCGCTCCCCTCTGGGAGGAGGGCTGCCCAGAGGGGTGCGGGTGTCGCTAGCGGCCCCTCCCCGTGTGGGGCCACGTGGCGGGTGCGGGCCGAGCCCGAGGGGAAGAACCTGGCCCGTGGGGAGGTGGGGGGGACCGAAACGGCGCTGAGCCGAGCCGAGAGCTACGGGGTTCGGAGCAGAGGCAGCGGCAGCGGCAGCGGCAGTAAGAGGGAGGGGAGGAGGCAGGAGGGCGCATGGGGCGCCCCGGCCCCTCCGACAGCGCGCCCCCTCCGGCCCGGCCGCGCTGAAAGCTCCCCAGCGCCGCGCCTTGAACCCACGCCCCGGGGCCATGCCGGTCATGAAGGGGTTGCTGGCCCCGCAAAACACCTTCCTGGACACCATCGCCACCCGTTTTGACGGAACGC
Seq A exon
GTGAGTGGGACGGAGGTCGGGGCTTGAGGTTCGAGCTGGGGGGCAAGTATCCTCGGGGCCGTCTCGGATCTCCTGGACATGGTGAGACCCGAGGCGAGGGGAGAGAATGGAGGTGCGGGTCTAGGAACTCCCAAAGCCGCGGTGCAGGAACAGGGCGGGGAGTGCCCTGCGAGGGGAGGAGGGGAAAGGGCCGAGAGCACGGGGGCCAAGGTTAGGGGGTGTGACTCGAGGCAGAAGAGGCTCTTTGTGCGGCAGAGCGGAGGAGGGTCCTTCGGAGCCGCCCACTCTCGGGCAGAGCTGTGCTGGGGGCGTGTATGGGGGTATCCGAGACACAGAAGTGGGGCAAAGTGGCCGGGCATTCTGGGGTCTACTCACAGACTCCAGCTCCCACTACCTCCAGAAAAAAAGGAGAAAAGATCAGACTTCAGCAGGACCTAGTTTGGATTGAGGTCGCGCGCCCCCAAATCGTGGGGCGTCAGTGTCTAAGGTGGGTGAGGCAGGAGGAGGGGAGCGGTCTGTGCGACGGTGGGAACTCCCAGCTCGCCCAACGTAGCTTGGGTTTCAGGTTCAGCACCTTGGACAGCCACATCACTCCTCCCCCGCCTCTTCTCCCGCCATTCCCTCTTCCCACTCTGGAACCCAGAGATTCCCCGCCCTCACCTCCCCCAACCCCGCCATTCCCTCGGGAACCCTGGCCGGGATCTGGATGGTGGGGGAGCGGTACCCGAGGGCGGAAACTGAGCCGCCGGGCCCTACCCTCTTCCCCACCACCTTGTTTCCATAGCGCCCATCACCGGGGCAACAGGCCCTGGGATGGAAGAAGGAGGCTGTGCCCAGAGCCCAGTGCCTCCCAGGCACCTTCAGTGTCCCCATCAGCCTCCCTGCCCCCAGACAGTCATCCCTCCTAGAGCACCAGGACTGGTTGTGTCACAGGCCCCATCTCTTAGCTGAGTCTCTGTCCCTGGATGGCCCACAGGAGTCCCCCTGGCCTCCCACCCATTGGAGCTGGAGGGAGACAGCTCGGGTTCTGCTGCTGGGGGTTGCTGGAGCTATACGCTCAATGCCCTCTCCCATTAGACTTTGAGCAGTGGGGCAGATCCCCTGAAAGCAGCTACAAGAATGCTAAAAAGTGGACCTTCTCTGGAAGGCAGGGAAGGAAGACAGCACTCATCACTGTCTGCCCCCACACTAAGGAGATCTGTGAGTTTGGATAATCTCTGCCTTTTGGTTTCCTATCAATAAATGGGTGTGGTGTCATCAGAATCTCTGCCCTGCTTACTCTGTAATAGGAAGAAAGCCAAGTGAATGTGGGGAAAAAATTTCACCTTCTCAGAGTAGCACTTACCATGTGCTAGGACTTGTTCTCCCCAAGTTAACTCATGTAACTCTCACAACGACCATGTGAGGAAGGCCTATTATGCCCTACTTTGCAAATAAGGAAAGCTTAGGCACAGAAGAGGTCATCAACTTGCCCAAGGTCACACAGTTAGTAAGTGGCAGTGGAGGGTTGCAGGAGCCCAGGCTCTTACTCACCATGCTATACTGCCTTCTACAGTGACAGCTCACCAGTTGGAAGGCAGGGGGATGGATGGCATGACCTCCTGGGGTCCTTCTCCAACTCCCCGTTAGACCCTGCTTAAGTCCTGTCTCAAGTCCTTGTCTCTTTGCTCCAACTTCTCCAATTCTCAATTCAGAATATCCCAAAGTGGGGTCAGGAGCAACATGGAAACCTGGGAAGCTTCTGGCTCTGTGACTTCTAACCCCAACTTAGAGGAAGTGCTGCCCACCTGGAAGCTAGCTCGCCTCCCAGCCTTGACCTGACCTTGACCTCTTCTTCCCACAG
Seq C2 exon
ACAGCAACTTCCTGCTGGCCAACGCACAGGGCACACGGGGCTTTCCCATCGTCTACTGCTCCGACGGCTTCTGCGAGCTCACAGGCTACGGTCGCACCGAGGTCATGCAGAAGACCTGCAGCTGCCGTTTCCTCTACGGCCCAGAGACCAGTGAGCCAGCCCTGCAGCGTCTGCACAAAGCCCTGGAGGGCCACCAGGAGCACCGGGCTGAAATCTGCTTCTACCGCAAGGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000089558:ENST00000264661:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.076
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF134261=PAS_9=PU(70.6=97.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTAAGAGGGAGGGGAGGAGG
R:
TCTCTGGGCCGTAGAGGAAAC
Band lengths:
350-2193
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development