HsaINT0084344 @ hg38
Intron Retention
Gene
ENSG00000089558 | KCNH4
Description
potassium voltage-gated channel subfamily H member 4 [Source:HGNC Symbol;Acc:HGNC:6253]
Coordinates
chr17:42170107-42171995:-
Coord C1 exon
chr17:42171788-42171995
Coord A exon
chr17:42170302-42171787
Coord C2 exon
chr17:42170107-42170301
Length
1486 bp
Sequences
Splice sites
5' ss Seq
TTGGTGAGC
5' ss Score
7.43
3' ss Seq
TGCATCCGTCCACCCTGCAGGCT
3' ss Score
7.82
Exon sequences
Seq C1 exon
ACCTCGCTGGTGCACCTACTGAAGACAGTGCGGCTGTTGCGGCTGCTGCGGCTGCTGCAGAAGCTGGAGCGGTACTCTCAGTGCAGTGCTGTGGTGCTCACGCTGCTCATGTCGGTCTTTGCGCTCCTTGCCCACTGGATGGCCTGCATCTGGTATGTCATCGGGCGCCGGGAGATGGAGGCCAATGACCCGCTGCTCTGGGACATTG
Seq A exon
GTGAGCCACCGACCCCAAACTTTCACAGACCACCTGTCCACCTGTCCCATCCCCAAGCTGATGCCTCCACCAGTACCCACACCCCTCATCCCACATTCCTCTATCCATCCAACAAACATGCGTTGAGCTCTTTCTGGATCAAGCATGGGAATATTGATTTGCAGACAAGGGCTCTGTTTTGGGGGCAGGTTGGGGGGAACTCACAGCCTAGTGGGGGAGCAAGACCAGTGATAGTGATCAAAGTACAACGCAGGAAACACTCTGAGGGTGGAGGGGTGTGTTTCAGGCAGAAGGAGCAGCACGTGAAAAGTCCCAGAAAGAGCTTAGCATCTCTGCCCCCATCAATCCCTTCTTCTCCAAGCTTCATGGCCATGAGCCAGGAGACAGCCCCAGGCCCTTGGAATCCCTCTGAAAGGCCTGTCAGATCCCGGGCATGGTCCCTGACACCTCCCTTTCCTTTACCCCACACCTAGCCCACCACATCAATACCACCTCTCAAATGTCCCGTGAATTTGACCTTTTCTCTCCATCCTCTCTGCCCCTTCCCAGTCCACTCCACCTCCCTTTCTCACCCAGGCCTGTGCAATAGCCTCCCTACTGATTTCCCAATCCCCTTCTCATCCCCCCCACAACCACCATCCTCACCACAGCCAAATGGGTGTTCCAGGATTCAACGTTGACCCACTACACTCCTTCTGGGATTCCTTCAGTGGCTTCCCACTGCCCTCCAAATGAAGTCCACACTCACTGCACACCCTGGGCGGCCCTGTGCCCCTTCTCTCCCCACCTGCCTTCCCGTTCTCCCGTGCTCCCTGCGCTGCAGCCACACCAGCCTCTCCCCTGGACCCAGGACATACTGCTTTCTCATGCTGGGCCTGGAACATGTTCTTTTCCTCTCTGGAATCCTCCTCTTTTGTCTTCCCTCTCCACCTAGATGGATTTTCCGTTCCCTGCCTCACTTGGAACAATGTTCCTTCGGTTCCATGTGTCTCAACCAAAATGTCCTGTCCTAAGGAGCATGCCTTCCAGGCACCATGTCCAGAACCCCCAACTGCCAATGGGTTGGCTTTCCCTAACCTGTTAGGATTCCTAACACACCCTATACAATACTTTCCTTCCAGGAGCTCACCTCCCACCTGTAATGATTTATGTCATGTCTCTTTCCCCTCCAGGCTATAGGTTCCACCAGGGCAGGGAGAGTGTTTGGCTGGGTCAATTCCCCAACACTTTGTATACAGCAGGTGCACAATAAACTATTAGAAAGTTTCAGGAGCCTTTGAACACTCAGCAATGTAGTTAGTTGGCGGCCTTGGAATGCAACTGTAACCAATGCACCATGGGGAGACACAGGCCCAGGCCACTCCCCACATTTCCTGTGCCAACCTGTGTATAAATACTTGCCGAAGGTCAAGCGTAGGTGGCTCAGGGAACCCTGGTTCTCCACCGCTGGCACAGCCAGGGCTCCCTGCATCCGTCCACCCTGCAG
Seq C2 exon
GCTGGTTGCATGAGTTGGGCAAGCGTCTGGAGGTGCCCTATGTCAATGGCTCGGTGGGCGGCCCATCACGGCGCAGCGCCTACATCGCGGCACTGTACTTCACTCTAAGCAGCCTCACCAGTGTGGGCTTTGGCAACGTGTGTGCCAACACCGACGCGGAGAAGATCTTCTCCATCTGCACGATGCTCATAGGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000089558:ENST00000264661:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=FE(32.9=100)
A:
NA
C2:
PF0052026=Ion_trans=FE(31.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGGTGCACCTACTGAAGAC
R:
TTGGCACACACGTTGCCAAAG
Band lengths:
351-1837
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development