HsaINT0084368 @ hg19
Intron Retention
Gene
ENSG00000173826 | KCNH6
Description
potassium voltage-gated channel, subfamily H (eag-related), member 6 [Source:HGNC Symbol;Acc:18862]
Coordinates
chr17:61615771-61619795:+
Coord C1 exon
chr17:61615771-61616023
Coord A exon
chr17:61616024-61619601
Coord C2 exon
chr17:61619602-61619795
Length
3578 bp
Sequences
Splice sites
5' ss Seq
TAGGTGGGT
5' ss Score
5.56
3' ss Seq
CCCACCCCTCTGGCTGGCAGGAA
3' ss Score
6.67
Exon sequences
Seq C1 exon
GTGCTGAAGGGCTTCCCCGAGTGCCTGCAGGCTGACATCTGCCTGCACCTGCACCGCGCACTGCTGCAGCACTGCCCAGCTTTCAGCGGCGCCGGCAAGGGCTGCCTGCGCGCGCTAGCCGTCAAGTTCAAGACCACCCACGCGCCGCCTGGGGACACGCTGGTGCACCTCGGCGACGTGCTCTCCACCCTCTACTTCATCTCCCGAGGCTCCATCGAGATCCTGCGCGACGACGTGGTCGTGGCCATCCTAG
Seq A exon
GTGGGTCCGGCGGAGTGGACCAGGCCTGTGTTGGGGATTGGATGGAAGAGGGCGGGATTGGAGATGCCCTGCCCAGGCCACCCTCTTCCTGATGAGGATTTTACTTTTACTGGCAGCCACTTGCACAGCATGTGCCCGGGAGAGCTTTAGACCCAGCTGGCTGAATCCTTAAAACAACCCTCTGCCGGAGGTCCCATTTTCCTGAGAGGGAAGTTGAGGCTGAGGGAGATCATGCTAGTCTGTGGCCAGGCAGGGATTCCAGGGCTGCCAGTGTGACTCAGAAGCCCAGGCAGGTCTTCCTACCTTCTTGCACTCTTGGGGAGTTTAGGGAGAAAGGCCAAGGGTCTTTCTGGGTGGAGGTGGATGCCCTGGCTGGGGACCCCAGTCTCATTCAGTGCAGACACAGGGATAGCTAGACACTTTGGAGGAAGGACATGAGCACTGGGCAGGGGGGACAGACAGGTCACAAGCAGCCTCTGTCACATACCTGCTGTGTGACCTTGGGCAAGTCACTTTGCCTCTCTGAGCATCACAGGGTCCTCTTGATTCTCATCTTCCTTGCCTGCCCCATGACTTCATCTCCACCCCAACTTCAGCCTCGCCCTCCTTTGGTACCCATGACCTGGCTATCCTCCAGCCCCTCTGGACAGGTTCCCCTCGGGCAGCCCTCCCCCTCTGCTTCCTCTGGACTGCTGGTGATCTGCTCTCCTCGCCCCTCCTCACCTGACACCCTCCCCTGGGCCTGCTCCTCGCTCCCACGGCTTCAGCCTTCACCTGTGCCACAAGGAGCCCTGTCCTCACCCCACTGTCTCCTTAGACCAGAATATTCCATTTCTTCCTGGGCATGGCCGCCCTAGTATTCTATGAACAGATCAAACTCAATGTATCCCAACCTGAAATCACCTTTCCTCAAAACCAGCTGCTTCAGCATCCCCATCACTGTGAAGCATCTGCCTATTGCCCACGCCACAGTCTGCCAAGGGGGCATCCTACTTCATTCCTGCCCACTGTCCACCAGCCAGACTTGTCCATACCTCTCCATCTCACACCTGTCTCCCTGTCCCTGCCTGGATCCAGCCCTCTTTGGGTCCTTCCTGGAAAGGTGTTGGGAACTCCTTTCCCATGGCCCTGCGTCTGGTTTACTCCCATGCCTGTCTTCCACCTTCTGCCAGTGACCTGAAATAGACATCTGTACATCTGCCTCTTCTGCTCAAGATCCCTCCACAGTTCCCCATGGTCCATGCATGGCATCCCCAGTTATCCCAATCCGACCACCCTGTCCTACCACCCTCCCCCTGGTACTTCATGCTCCAGCCAAACTACTTAGAGTTCTCTAAATCTGTGCCCTTGCATGTGCTGCCATTCTGCCTGGAGCGCCCTACCCTGTGCCAGTCCGGCAGATCCCAGTTGTCCTCCAAGGCTGGGCTTAGGCACAGGTTTCTGTATGAGACCTTCCCTCACTCCCAGCCTACCTTAGACGTGCCATCCATGGCCAGGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGATCACAAGGTCAGGAGTTCAAGACCAACCTGGCCAAGATGATGAAACCCCATCCCTACTAGAAATACAAAAAATTAGCCCGGCATGGTGGCGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGAGAATTGCTTGAACCCAGGAGGTGGAAATTGCAGTAAACCAAGATCACGCCACTGTACTCCAGCCTGGGTGGCAGAGCGAGACTCTGTCTTTAAAAAAAAAAAGTGCCATCACATGGGAGGGATGATTATTATTATTAATAATTAAGAAGTTAATCCAATTTAAGTTTCAGTTAGAGACATGAAACCTCTCATTTTGTCCTGAGTAGAAAAAGACACTAGATCAGAATCTTTCATCTACTGGAAAACCATCACATTATAATGTTGCCCAGATTTCAAGCTTCAGGGTTTCATGTGTGACCCTGGCAAGCCGCTTCCCTCTCCAGGCCTCAGCCCCCTCCTTTGTGAATACCCTTTGATCCTGTTCTCTTGTGGGGACATGTCTCAGCCTCCACCCATCCTTCTGTGCTAAACTGTTACTGCCACTTGCACTAACAAGTGGACTTTCTGGGGGAGTGGGAATCAAAGCAGTCATGCTCCGTGGCACCCCGGCCCTGGGCTCTCCACCCCTGAGCCCTGACAGTGCAGTGCTGATCACATGCTGTTTCTTCTGTCCTGACTGCCTTTCTCATGGGGGCTGGTCCTTGTTTCTCTCGACACAGCCCCCACTTCACTTCCTCTGTAAGCCCCCTCCTCTCTGCCCCAGCCACCCCTGGCAGGAGGAGCCCCTCCCTCCTCCATGGCCCCATAACTCTTGGTTCTTCCTGTTTCTAGGGCTCTACAGATCATGCTGTAAACTTGTTGGCTGCTTACGTACCTATCTTGCAGGGATTTGGGAGGGTCCTTGTGGGTGGCACAACATCTTATATTTATATCCTTTGGCCAGCACAGCACCTGGCACCAGGAGGGCCCAGTACCCTTGCCACATACCACATACCTGAACATCACCCATGTCTACCCTGGGATATTCCCCCTTGCCTTGCATGGACCTAGTCAGGTGCCTCTTGCTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCCAGGCTGGAGTACAGTGGTGTGATCTCAGCTCCCTGCAAACTCTGCCTCCCGGGTTCAAGTGATTCTTCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCCACCATGCCCTGCTAATTTTTGTTTTTGCTGTTGTTGTTTTTAGTAGAGATGCGGTTTCACCGTGTTGGCCAGACTGGTCTCGAACCGACCTCAAATAATCCACTACCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCGCTGAGCCCTGCTGCCTGTTGCTTTTTGAGTCACTTTCTCAAGCATCACCTCATCTGCTTCCCTGAACAGTCCAGTGGGGTTGGCAAGGCAGATCAGGTTTTATCCATTTTAGAGATGAAGACTCTGGGGTCTAGACAGGGGGAGTAACTTCCCCAAGCTTCCTTCACCAGGGCCATGCTGGTTACCTGGCCCCACAATTGGGAGTGGGAAGACAGAGAAGCCTCTGGCCCTGCCCTGGCGGAGTTAGGTGCTCTGGCCCTGGGTTCCCTGCACCCTGCTCCACAGCACTGGCAGGCCAAGCAGCAGGAAGACGTTGAGACAGATGTTGAGCCTTTAGGGCCCCTTCCTGCCCACTGTGCCAAAGAGTATGGGCTACAGGAGGGAGATTCTGATGGAGGGTGGTTCTGAAGGGCCTGGAGACAGTGAGAGGAGCCACACGCCGGATCTCTGTGCCGCTCAAAGGACACAGGAAGAGAACAGCCCCACCCCTACCCTGCCACCCACAGCCAGCACATCCAGCCATGTCCCCAGAGCTCTATCCCAGGCAGCAGGCCCCGGCCTAGAAGGATGTCCGAGGTTGGGGGAGGTCACGGTCAAAGGACCCTCATAAGGGAGCATGGAGTCAGACCCTGAAGAGACTCCCACCCCTCTGGCTGGCAG
Seq C2 exon
GAAAGAATGACATCTTTGGGGAACCCGTCAGCCTCCATGCCCAGCCAGGCAAGTCCAGTGCAGACGTGCGGGCTCTGACCTACTGCGACCTGCACAAGATCCAGCGGGCAGATCTGCTGGAGGTGCTGGACATGTACCCGGCCTTTGCGGAGAGCTTCTGGAGTAAGCTGGAGGTCACCTTCAACCTGCGGGAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000173826-KCNH6:NM_030779:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0002724=cNMP_binding=PU(45.5=47.1)
A:
NA
C2:
PF0002724=cNMP_binding=PD(53.4=72.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)