HsaINT0088947 @ hg19
Intron Retention
Gene
ENSG00000111796 | KLRB1
Description
killer cell lectin-like receptor subfamily B, member 1 [Source:HGNC Symbol;Acc:6373]
Coordinates
chr12:9751095-9752437:-
Coord C1 exon
chr12:9752363-9752437
Coord A exon
chr12:9751250-9752362
Coord C2 exon
chr12:9751095-9751249
Length
1113 bp
Sequences
Splice sites
5' ss Seq
CAGGTAATT
5' ss Score
8.55
3' ss Seq
ATTTCTGTTTTTTACTTTAGAGA
3' ss Score
9.13
Exon sequences
Seq C1 exon
TGACATCCTTAATACAGAAATCATCAATAGAAAAATGCAGTGTGGACATTCAACAGAGCAGGAATAAAACAACAG
Seq A exon
GTAATTGTGTGGCTTCAATTTCCTAAGAATAACTGTTAATATTTGGTAGATTTCATGTGTTACCTTAGGCACAATTCATAACAATCCATATGTTAAGATATTCTTATCATTCTGCTTTTCTGGATTAGAAAATTGAGACATAAAAAGATTCAACAACTTGCTGAGGGTCACATAAGCACCAAGTGATGAGGCTGGGAATTATATGTAAGTGGTCTGACTTATGAGCCTAAGGTTTTAACCAGCAAGGCATGCTGCCTCATGAGGAGCCTCTGCTAGGATACTCCACTGTTGATAGGAAATATGTGAAATATCTGATTATTTTAGTGAGCTGTTAAGTTTGGTCTGAAGTTAATTGATAGAACTTAAACATAGAATGAATTCTTTACTATTTATTATATTTCCTCACCATGCAGCCACATTAGTCTTGTTCCAGTGTGTGTTAATAAAAAAAGGTGACTACTGTTGAGTGACTATAGTGGAATATGATCTGTGTGCACATTCTCACAGAATGGAAGTTTTAAGAAAACCTGAAAGTCCTTCTGGAAAATTCTATCCAATAGATCACATTAAGTAGGTAAATACATCGTTTAGCAATTGGAAATTTTCTTATAATTTTTTCTCCATGGTATTTCTTATTAATTTAGTGAAAATAATTATTTGCTATGCATTTTGTGCATCATTTAAAGTCAGTACTTTTTACATGAGTTTTATATTGTTGCCTGTGCAGTGAAACAGGCACTGGTGATGAATTTAAGGAAACTGAGAAGTAGTGGGAAATATTTCATCTGACTGGCTGGACTTAAGTTATTCTGTCTCTCACTGTCTTAAAATGTAAGATGTGGCAGTTTAAATTATTCTGATGGTGTTTTCCTATTTTAATATTTTATGATTCCATTTATGCTCAAGATAACTGGTCACTAATTCCCAATTCTTGGTACTAGAATGAACAGTAGGTCTCAAAAATCTCAACTTTATAACAAATTCATTGTTCTCACAGTGATAATCAAAAACTTTGAGCATTTATAATGACCTGTGTGTGTGTGATTGGTTGTGGTGTGTCAGGGATAGGTTAGAAATATAACATTTATTTCTTATTTCTGTTTTTTACTTTAG
Seq C2 exon
AGAGACCGGGTCTCTTAAACTGCCCAATATATTGGCAGCAACTCCGAGAGAAATGCTTGTTATTTTCTCACACTGTCAACCCTTGGAATAACAGTCTAGCTGATTGTTCCACCAAAGAATCCAGCCTGCTGCTTATTCGAGATAAGGATGAATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000111796-KLRB1:NM_002258:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0005916=Lectin_C=PU(26.5=51.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCATCAATAGAAAAATGCAGTGTGGA
R:
TCATCCTTATCTCGAATAAGCAGCA
Band lengths:
206-1319
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)