HsaINT0090396 @ hg19
Intron Retention
Gene
ENSG00000091136 | LAMB1
Description
laminin, beta 1 [Source:HGNC Symbol;Acc:6486]
Coordinates
chr7:107621054-107626530:-
Coord C1 exon
chr7:107626467-107626530
Coord A exon
chr7:107621257-107626466
Coord C2 exon
chr7:107621054-107621256
Length
5210 bp
Sequences
Splice sites
5' ss Seq
AGAGTAAGT
5' ss Score
9.35
3' ss Seq
CTTCTTGATGACCTTCCTAGATT
3' ss Score
4.71
Exon sequences
Seq C1 exon
GTGATATTTCGTGCTTTAGATCCTGCTTTCAAAATAGAAGATCCTTATAGCCCAAGGATACAGA
Seq A exon
GTAAGTTCATTTTCAAACAAAAGTGTTTTTTGTTAGTTTGTTTGTTTGTTTTGTTTTGTTTTTTGAGACAGAGTTCCGCTCTTGTTGCCCAGGCTGGAGTGCAATGGTGCGATCTCTGCTCATTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTAAGTAGCTGGAATTACAGGCATGTGCCACCACGCCCAGCTAATTTTGTATTTTTAGTAGAGACGGGGTTTCTCCATGTTGGTCAGGCTAGTCTTGAACTCCCAACCTCGGGTGATCTGCTCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGCCTGACCCAAATAAAATTTTTTGTTTGTTTGTTTTGTTTTGTTTTGTTTTTTTGAGATGGAGTTTCACTCTTATTGCCCAGGCTGGAGTGCAGTGGCGCGATCTAGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCCGCCACCATGCCCAGCTAGTTTATTTTTGTATTTTTAGTAGAGACGGGTTTTCACCATGTTGGCCAGGCTGGGTCTCGAACTCCTGACCTCAGGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAACCAGCGCGCCTGGCCCAAATAAAAGTTTTGATGGTAAACAGCAGCCATGGAATAAGTCTTACTCAGAATCTAAATATTCAGTGCTAAATCTACCTTTTTCATTTTCCTTCTTTCTCTGTGTTACCTGACCAGAGGGTCTTGAAATTAGCAATAATTACTCTCCACTGATAGGGAATACATTTACATCTGATATAAGATGTAAATACAATACATCCGATATAAGATTGATAGGTTATCAAGTAATTGTGTTGATCATAATACCTTATTTTATTGCTCAGTATATTAGGGTATATATTGGGCTTTTGTATCAAAGAGTCTCCCCAAATCTAGTTGTTCAAATAAGGTGAAAGTTTCTTTCTCTCTTACAAAACCCACCAAAGAGTTTTCTAGAGAAGAAGTGTAGCTCAATTGCCATAATTAAGCTTACCAGATAAAATACAGGATGATGCCCAGTTACATTTGCAAATAAATAATTCTTTTTTTTAGCATAACTATATCCCATATATCCCATATAATATTTGTGACTAGTACAAGTGTGTCTCATGCAATATTTGTGGTTGGTATAACCATGTCCTATGTGATATTTGAGACATACTTTATCCTAAAAAATAGTTGTTTATCTGCAATTCAAATTTAACTGAGTGTCATTTATATTTACTTGTTAAATCTGGCAACCCTAGTTATAAGGCCATCCATGTTTCCAGGTTTATTCACATGGTTAGAGTTAGACCACCACCACTATGTCCTCACCTCAACTCGGGAGAAGAGGGAAGACGAGGCAAGCAAATTCCATTTAAAGATGAGACATGGGCCAGGCGTGGAGGCTCACTCCGTAATCCCCAGCACTTTGGGAGGCCAAGGCAGGCGGATCACTTGAGGTCAGGAATTCGAGACTAGCCTGGCCAACATGGTAAAACCGTGTCTCTACTAAAAATATAAAAATTAGCTGACATGGTGGCATATGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGAGGTTGCAGGGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAACAAAAAAATGAGATGTGGAAGTTGCACACGTCACTTCTGCTCACATCTCATTGGCCAGAATTAGTCACGTGGCTATACTGCAGGAGACACTGGGAAACATCTCTAGGTGTTTCATGTGCTCTACTAACACTCTTGGCGAGGGCTCTTACTGTCAAAGGAACAAGGGAAGAAAGAATACTGAAGAGAAATCAGAAGTCTCTGCCATTCTCAATATACTCAATAAAATGAGGGTTGCATTTCCGTTTAATAGAAAAATAAGCTGAAGCTTATAGAGTTGGATGTTATTACGTAAAGTGATATGGCTATTAAATGGCAGTCAGATCTTGAATCCATATGTTACGGTGCTCAGTTCAGAGCTCTTTACCACATTCAACAACTGCTCTTATTACACAATTACATTTTAATCTTCTTGGGAGGCATGTATGGTAATTAAAAGAATGGGCTCACTGGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTGAGAGGCCTAGGCGGGTGGATCACGAGGTCAGGAGTTTGAGACCATCCTGACCAACATGGTGAAACCCCGTCTCTACTAAAAATAGAAAAGTTAGCCAGGTATGGTGGTGCGTGCCTGTCGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCTGAGATCACACCATTGCACTCCAGTCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAGGGCTTTGGAGTCACAAAGTCCTGGATTTAAATGTGTTCATAAATCATAAATGTGTTCAGTACATCAAAGCTGTTGCTACATTTGTTGCTGTTGATGTTGCTGTGACTATCAGCTTTGGTTTGGGTTTTGCACAGGACTAGTTCCAAATGTTGGAATGAAAGGTGAGCCTGCCTCTCCTGCTACTAAGGTGCAACCAGTTGAGTAGAGGCGGGGCTGATTCTTGCTGATCTTTCCCAGCTGCACAAGGCCCTATTTTTAACCAAGGCCCCAAAAAACTTCCAAGCTTGAAGCAAGGAAGAGTGGAGTGGAAGAAGTCCAGGGAATATTGCCAGAAAAATGCTGCTTCCCCATTTAAATTAATTTTACATGTGGCCCAGCCTGTCTCTGGTCTGTAATTTACTCATTCATTCTCTTGTAAAACAAATATTTAATAGATGTGTCCAGCTCTGTGCCAATTTCTGAGTGAGCCATGAGGCCTTTCCTGCATGTCTCAAAATGCAGTTATGAAAAACGTCCACAAGGGCTCTGGGACAGACACCCCCTAAGTCCCTAAAAGGACTCAACCATCTGCTCCCTTTAAGGTGAAATTTGTGGGACTTGGAGGATGTGTTGTCTTTATAATTTTGATTCTTTTGTCTTTTGTGGTTAAATGACATCGGAGAATCTTTTTCTATGTTACGGAAGCATGCATGTTAGCTGATCATGCATTTGATTTACTTTGTAATCAAGGGAGCAATATCTCTTTAGTTGTCTATTGTTGAGACCTGAGACTCACTTCAAAAGTGATTTGCCACTTAGAATAGCAGTCAAGATGAGGCTCGCTTTTTAAATATGGCAGGAGAGAGTGGGGGGAGCATATTTGCTCTACTGAGGGGTTTCCACAAAGGTCAGTTCAAGGGTTTCTAAATACTCCAGCTGCTCTTCAAGTTTGTTGTTTGGCCTCTTGTCAATAGGCGCTTGTGCTCATTTTGTGCAGGAGGATTTGTGCAGGAGAAAATGTTGGCGTTCATAACTGCCATTCAGTTGGGGAGTACCACGGTTTCTCTGTTTAGTTTTTGATTTTACAAAGAACCTAAGTTTAACACATGGACTTTTCCTTTCTACCCGCAGCCATTTCTATAGCTTCATTGTAAGCTATGCATGTATTAAAAGCATTTGAAATTGTATTTGGGCTGTGAAAATATCTGATGTACTGGGCCACTACCCTGTTGTCTTATGTTGTAATTTATAAGAATGCACAGACATAAATGACAGTAAAGAACCGTTTCAGGCTACAGAGCTTGAGAGTGCAGACAGATGAATCAATCTCTGGGGATCCAGTTCAGCATGAAGAACTTAGTAACTCACGAAAACCCCGTGGAGAAGGTTGAATGGCTCTTCGTTTGTCTAGTTACTATAGAATGAATTGGTAGCCCAGCATTTACAATAAGCAGAAGTCTGCAGACCTAGGAAGAAGAGGGAAAGATAAAATTGATTTAGAGGTAACTTGTATTTGAGAAAAAATAATTTGCCCCACATCCTAATACTAAGCTTATTTATGCTTATGTCACTATATAATATTGAGAAACGTGGAAACGTTTTGTAAAACTGGGACAAAAAAGTTGTGGACCAAAATGTTGCTTAAAAACTTGAAATGTTCTCTCCTTAGGTTGTAGTTATTCTATAGCGTTAACACTATTTTGGTAACTTGGATGTCATTTAAGCGGTGGGAAATTTCAAATTTTCCCTTCCAAAAATAGAGACAAAAATGTTTCTAACTATCTTATAATAACAATGAGAACTGGAGTGCTTTGATAAATCTTTTCCTACCTGAATGGAATTTTCTCATGTTGAAACTGACATTAATTGCTGTGGGAAGCAGATGGCATTGTGCTACTTCAAATTACTGTCTGCCCGCAGGTTCCAGCAGTCATGCAGCTGCGTTCTTATAATTTCTCCACTTTCACACTTCTTCCTAAATAGCTGTTCTGCAAACAGACCCATCACAGAATAGCTACTCTTTTTTGTTGTCGTTCAGGCAACTCTCCTGCCTCAACCTCCAGAGTAACTGGGATTACAGATGCCTGCCACCACACCTGGCTAATTTTTTTTTTTTTTTTTTAAACAGTTTTGCTCTTGTCGTTCAGGCTGGAGTGCAATGGCACAATCTCGGCTCACTGCAACCTCCACCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGTCTCCCTAGTAGCTGGGATTACAGGCGGATGCCATGATGCCCAGCTACTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGTCAAGGCTGGTTTTGAACTCCTGACCTCAGGTGATCCGCCCACCTCGGCCTCCCAAAATGCTGGGAATACAGGTGTGAGCCACCGCGCCCGGTCTAATTTTTGTATTTTTTTAGAGATGGGGTTTTGCCATGTTGGCCAGGCAGGTCTCGAACTCCTGACCTCAAGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGGAATTACAGGTGTGAGCTACCACGCCCGGCCGACATTCTTATGAAACTGATGAGAGGGCAGTAACCTTTCCTCTTTGCAGTCATGTTATGTTAGGCTTCACTATTGGAGTCATCTAGATCATACAAGAGGAGGAACTTAAGCTATTTTCATGTGTCATGCCTTTCTCTAAAAAGAAATGATGCAAGGAAAAAAAAAAAAACTTCTTGCTTGTCTGATCAGACTTTTCATCTTCTTGATGACCTTCCTAG
Seq C2 exon
ATTTATTAAAAATTACCAACTTGAGAATCAAGTTTGTGAAACTGCATACTTTGGGAGATAACCTTCTGGATTCCAGGATGGAAATCAGAGAAAAGTATTATTATGCAGTTTATGATATGGTGGTTCGAGGAAATTGCTTCTGCTATGGTCATGCCAGCGAATGTGCCCCTGTGGATGGATTCAATGAAGAAGTGGAAGGAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000091136-LAMB1:NM_002291:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005512=Laminin_N=FE(8.9=100)
A:
NA
C2:
PF0005512=Laminin_N=PD(18.3=63.2),PF0005319=Laminin_EGF=PU(35.5=32.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)