HsaINT0095570 @ hg19
Intron Retention
Gene
ENSG00000134013 | LOXL2
Description
lysyl oxidase-like 2 [Source:HGNC Symbol;Acc:6666]
Coordinates
chr8:23217603-23225947:-
Coord C1 exon
chr8:23225510-23225947
Coord A exon
chr8:23217779-23225509
Coord C2 exon
chr8:23217603-23217778
Length
7731 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAAC
5' ss Score
8.14
3' ss Seq
CTCCTCTCTGCCTCCTTCAGGGC
3' ss Score
10.95
Exon sequences
Seq C1 exon
AAAGCTCCTGCTGCTTCTGTACCCCGCCTGTCCCTCCCAGCTGCGCAGGGCCCCTTCGTGGGATCATCAGCCCGAAGACAGGGATGGAGAGGCCTCTGTGCTCCCACCTCTGCAGCTGCCTGGCTATGCTGGCCCTCCTGTCCCCCCTGAGCCTGGCACAGTATGACAGCTGGCCCCATTACCCCGAGTACTTCCAGCAACCGGCTCCTGAGTATCACCAGCCCCAGGCCCCCGCCAACGTGGCCAAGATTCAGCTGCGCCTGGCTGGGCAGAAGAGGAAGCACAGCGAGGGCCGGGTGGAGGTGTACTATGATGGCCAGTGGGGCACCGTGTGCGATGACGACTTCTCCATCCACGCTGCCCACGTCGTCTGCCGGGAGCTGGGCTACGTGGAGGCCAAGTCCTGGACTGCCAGCTCCTCCTACGGCAAGGGAGAAG
Seq A exon
GTAAACGCTCTGTGCTTTGGATCTGAGTGCTGTCACCTGGCAAGGCCCGGAGTGGCCTTCCCTGAGGTCAGCCTGGGAGAGGAGGCTGCACGCACTGCGAAGTGTAAATTCTTGGTGATGCCCATCCAGGGACTGGCATCCTTCTGTGCCCACTCAGGCTGCACCCTGCAGGAAGGCGGGGTCGGGGGGCTTGAGGAGGGGCACAGTAAGTGACCAACCATACTGATTTGCCCAAGACTTTCCTGGCTTTAGCACAGAAAGTCTCACATCCTGGGAAAACCTCAGGAAAACCAGGACAGTTGGTGACCCCAGGTAGGGGGTGAAATCGGCCTGTGCTCCTCTCTCCGCCCCATATGCCCTGCCTGGGGGCTGCGTCAGCCCAGAGGAAGTTGCGCTTTACTCCAAATCGTTCCCTGTTAGGAAAGCCTCTTGCTCTTCCTCACAATGGCTCCCACATGCTGGAGCTCCCTGACGCCCCCCACCTTCCTGGCATGTGGAGTTCATCGTTTTCACACTAACCTGCTATTGTGGGCTTGGTCACAATAGGCACACAGATGCTTTGGGTTTTTCACCGTTGGTTAGCCTATTCTTTCCTCCCTTGTGAGGTTCAAATTTATTAGTTTATTTTTAAAAATTGTTTTAAGAGCTGGCCAGGCGCAGTGGCTCATACCTGTAATCCCAGCACTTTGGGAGACGGAGGCGGGATGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGGGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGGGCATGGTGGCGAGTGTCTGTAGTCCCAGCTACTCAGGAGGCTAAGGCACAAAAATCGCTTGAACCCGGGAGGCGGAGGCTGCAGTGAGCCGTGATCGCGCCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAACAAAAAACAAAACAAAAACCCAAAAAATTGCTTTAACAGCTTTGAGGCAGGACAAAGTTTGAAGCCCTGAACCTAGAGCTCAGTCTGTACTGACCTCTGACACCACACTTTGTAGGAAGACGCATGTCCTCTCCAGCCTCATTTTCCCCATCTGGAAGTTGGGCTAAGAACCCCTGAAACCCTGACAGTGTATGTTCCCAAATAGGAAAGAGATAAGGGTGGAGGGAATTGTTTCTTTTTAAACATTTTTCCAGGAGCTAAGAGTTTCCTATCTCTGGGTCAGCCAGGCAAAGGAAGCTCCCACACCCTCCCGCCCGGCTGAGCTGCAGCCCAGACCTCAGCACAAGTCTGGCTACTGGACTAAAGCAGAGCTGCCTATACTCCTGTCCTGGACTAAAGGGCTAATGCCATGCTGACTGCGTAAGAATCGCCCAAGGGAGCTTAAAAGTACAGAATAGCGCAGACCTCAACCCACCATAATCTAGTTTAAAAGGTCTGGGCTGGAGCCCAGGACTCTGTCTCTTTTGGAAGTCTGCAAAGTGACAGGTTTGGGAGTCATTGAAATTGATAACTGTTATCCTCCCTTCCAACTTTTCTGTTATTCTAGAAATTATAGGAGAAAGGAAGTCCCATCTCATACACATCTCACCTCCATGCAATTGAAAATTTCCTTTTGGGGTAACTGGATCAGGAGACAGCACAGAGTCAAATGTTCTCTGCAGCTTGCTCTGGGCGATGAGAGCCACAGCAGTGAAGTTAGCAAATGCTGGGCTTTAGAACCCACTTCCTGTCTTCTTTAAACAAACGTCCGATACTTCCACATCTCTGTTTATCCGGCTGGCTGAGCGATCCAGGGGTAACCTCAGATTCATGTTTTCCATTCCAGGCTTTCCAACGCTCATTATTTTATAACAAATGCTTTCCAGTGACTGGGTATTTTTCCAGTGACAACTTAATTTTATTTCAACCTCAATTTAAAACACCTGTTGTCAGACAAGGGGGTTGTGGTTTTTCCCTATCAGGAGCAGGCACGGGGTAGTAGGAGACAGGTTTTTACCCAGGTGGGACTTTGCCATCCAAGCGTGGTGAAGAGTGAAAAGTTCCAAGGAGTGGAGGGAATATGAAAGGGAAGGATTAAACTCATGGTCCAAGGAGACTGTGCTGGGTAAGGAGGGTTGTAATAAGTGGAGAAGTTGAAGGATTGTGCATAGCTGCTGTGATCACTGGATTGCGAGTCTCTGTTCAGATGGAGATACAAGAAGTTTACTAAAAGATGAAGGGAGCTGTGTGTGGGTGCAGAGCAGGAAAGGTGAAATGGAGATTGAAGGGTGGGTGCAATCTCTGGTAATGAGAGACCTGAGCTATGACCATGGGACAGCGGCTGGAGCAGGATGGAGGACAGTCTCTGAGAGAGGAGGTGTATTAACGAAGAGACCAGGAGTACTGGAAAGGTCATCTTTGTGGACATGGAAATCATCAAGGTTTATAAAAGGAATAACATCAAAGAGAGGAGAAAGAAACAGATGCTTGAAAAAAAAAAAACTCTGTCTTGTGTTCACGGCTTTACGAGTTAAGCTGCTTACGTGAAGTGGTGCTTCGTTTATGACATGAGAGACCTTTTTACATCTAAATTTATTTGAATTTCACCAGCATCAGTCCAGATCTTTATCACTGGGTACATGGTGGGCACTCAGTGAATATTAGCTAATTGATTCATTTTGATTTGGCAGAATAGGAAAAAGAGTTGGCAAAAGAGTTCTGGGTATAGTGAGCACAGAAAGTGGCCAGCGCCCAGGGCTTGCTCCGGTGGGGCTTAGGGGCTTAACGTGCCGGTCAGACCGTGGATAAGACTGCCCCTCCAGGACCCCTCAAGCTCCTCTGAACTTCAGGCTGGAGCAGTGAAACCAGGGAGGGCACCAGGGACGTTCTGGGTTTTCTAGCCTGGCCTGTTCACAGACTGTTCTCCCAAAGCATCTCTGAGCTCAGGTAAACCACAGGCCCTTTTAGGGAGTTCTGGAGGGAGCAGCTGTCCTGATTCTCAACCCCTGTTCGAGGTTATAGCAGCTGAAGCTAAGGTGGTTGCTCTCCTTCACCTGTCTTCAGAATCAGGAGGCTAAGCCTATTCCCAGTCACATCCCTCATTCTTTAGACCACAGCGACGAAGCCAGCGATAACCACATTGTTGTAACCCCACAGATTTTTTTCTTTCCTTTTCTTTGAGACAGAGTCTTGCTTTATCACCCAGGCTGGAGTGCAGTGGTGGGATCTAGGCTCACTGCAACCTTCGCCTCCCGAATTCAAGTGATCCTCCCATCTCAGCCCCCCGAGTAGCTGGGATTACAGGTGTGCGCCACTAGGCCCAGCTGATTTTTTTAATTCTATTTTTAGTAGAGACGGGGTTTTCCCACGTTGGCCAGGCTGATCTCAAACTCCTGGCCTCAAGTGATCTGCCCACCTTGGCCTCCCACAGTGCTAGGATTACAGGCGTGACCCACTGCACCCATTTGTGACCCCACACAGTCTAACTTGAATAATATCCATTGTCCTGGGCTCTGGCATTCCAACTGAATTTCATTTATGATTTTCACCTTCCTAATGATCTGTTAACTTGTATATATATATTTATCTCTTCTTTCATCAGGAGAGGCATTGGAAGCAAAGAGTAACATAAAATTTGGCTTCTGATTGAATGGCTTTCTTGTGTCCAAAGTTTGACTGTCATCTTGTGTCCCAAGGACACGGCTTTCCTGGCAGCTCTGAGGAGGCATCTACTGGATTGTACCTAGAACCGCCCTGCTTTTCAGCAGGCAGACCCAGAAGCTGGTTGCATTGGAATCGGAGTAGTCTAGTTAATAAGCACTAAGCCTGTAGAGGGAAAAAAAAGGGCCCTTTGCAGTGGCTCATGCCTGTAATCCCAGCCCTTTGGGAGGCTGAGGCAGGCAGATCACCTGAGGTCAGGTGTTCGAGACCAGCCTGGCCAACATGGTGAAATCCTATCTCTACCAAAAAATACAAAAATTAGCTGGGCATGGTGGCATGCGCCTTTGGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGAATTGCTTGAACCTGGGAAGCGGAAGTTGCAGTGAGCTATGATTGCACCACTGCACTCCAGCCTGAGTGACAGAGTGAGACACTGTCTCAAAAAACAAAAAAAATTTTGTTATGAAATCAGGCCAAACGAGTATACCATGCATGGTGATGCTGTCTTGGGCTAAGTACAGATTCACATATCTGCCATCTAAGTAGAAATTGACCAAGCATATGTGGAAGGGGTCCATGGAAGATTATTGGGGGTCCATGGAAGTTTCATAAGAGAGCAGCTCTTTGGGGCAGGCTCCTTAGGGTCTCTGGTTTGCAGCTGTTCTCAGTTCCTTTGATGATGCACTGGTCGACTTCCAGGTCCTTAGCGAGGGGGGTTTCTCTCACTGCAGATGGAATAGGGTGCCACTGCTTTTCACCATCTCTGTCACTTTGGCAGCTTTGCGACAGAACATTCCGCTTAGAACATGGAGGGTCTTCCCTGTTGCTAGTAACTTAGCAAGACAAACATTGGTTTGTTGTTGAGACAGCAATCGATTAGGGAGTGTATGTTTCAGTGGAGCTTGACTGCTTGGAAACCGGGCCAAAATGAGAAGCCAGTTGGAAAACCTCAGCCCAGATGTTTTCAATTAGCTCTTTGTTCTCCACAATGGATCCAAGGTGCTGTCGTTTGAGCCCTGACCAGCAGCCGTGAGAACAGACACGTTTCAGCAGGGCCTGGACGTCAGGAGACTGGCCCCGGGGTGCTTATCGACCTTGAAGAGCCTCCGTTTCTTTCCTTGGTTTTCTAATCTCTCCAATGGGAATGTTTTTATTTGCTTTTCTCTTACATCGTGGAAGCAGTAGAATGCATTGCTTTTCTGAAGGACTGGAAGAAGGAAAGGGAAAGGGAGGTTGAAAGCGTACCAGGCACATACATTACCTCATTGAGTCTCCATGGCAACCTGTTTGCTCAGCATCATTATTTTGCCTTTAGAAATGAGAAGCAGGTGTGGTGAGGTAGTCGACCACATCACACAGTGCCCCAGTGTGTGGCAGATGGAACTTGAACCCAGGTTTGTTTGACTATGTCTGCTGCTCTAGACTCCTAAAAGGAGCGGTGAGAAAAATGAGAGGTTTAGATTTGTTTTCTTTCATTTTGCAGTGGCACTTATAAAAATCACTATTTGAAAATCCTCTAGCACTTTATAATTAAAAAAAAATTATGGCCAAATGTACATCACATAAAATTTACCACCTTAACTTTTTGGATTTTTTTTCTGGAGACAGGGTCTCCCTGTCACCCAGGCTGGAATGCAATGGCACAATCACAGCTCACTGCAGCCTCAACCTTCTGGGCTCAAGCAATTCTCCCACCTTGGCCTCCTGAATAGCTGGGACTACAGGCGTGCGCCACCATGCCCAGCTAAATGTTTTGATTTTTAGTAGAGATGAGGCCTCGCTATATTGCCCAGGCTGGTCTCGAACTCCTGAGCTTGAATGATCCTCCCGCCTTGGCCTCCCGAAGTGTTGAGATTACAGGCATGAACTGTGCCCAGCCCAGCCTTAAACATTTTTAAGTGTCCAGTTCAGTAGTGTTAAGTATATTCACATTGTTGTGCAACCATCATCAGCAGAACTTTTCCATTTTGCAAAACTGAAACTGCACCGATTAAACAACCACCTCCATTTCTTTCTCATCCCAGGCCCTGGCAGCCACCACTCTACTTTCTGTTTCAATGAATTTGACTCCTCTAGATACCCCATACAATATTTGTCTTTTGGGATGGGCTTATTTCACTTAGCATAGTGTCTTTATTGCAGCAGGTTTCAGAGTTTCCTCCCTTCTGAAGGCTGACTAATATTCCATCGTATGGATAGACCACATTTTGTTAATGGAGACTTGGGTTGCTTCCACCTCTTGGCTATTGCGAATAATACTGTTATGAACACAGGTGTGTAGATATCTCTTAGAGACACTGTTTTCAATTCTTTTGCTGGATCATATGGTAATGTTATTTTTAATTTTTTAAGGAAACACCGTACTGTTTTCTATAGTAGCTGCACCATTTTGTGTTCCCATCAACAGTGCACAAGGGTTCCAGTTTCCATACCCTTGCCAGCACTGTCATTTTCTGTTTTTTTTGTTTGTTTTGTTTTGTTTTGTTTTGTTTTTGAGACGGAGTCTTGCTCTGTCACCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAACCTCTGTCTCCCGGGTTCAAGCGATTCTCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACGTGCCACCACGCCTGTCTAATTTTTTGTATTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCCTGATCTTGTGATCCACCTGCCTTGGCCTCCAAAAGTGCTGGGATTACAGGCGTGAGCCACTGCCTGGCCCATTTTCTGTTTTTTTGATAGTAGCCATCCTAAGGGTGTGAGGTGGTGTTTCACTGTGGTTCACCCTCTAACACTTTGCACGCTGAATTCTCTACTTAGTGCAAGTGAGGCAAAAAAACAGGAGGTAAGCAGAGTCCCTTGGCGGCCTTCTGAAACATGATGAGGTGGCTCCGTGGGCCAGTCTGGCTGGGCTGTCTCTGAGCCAGCGATGGGAAATATTGGGAAGTAAGAGGAGCTGAATAGGAAGTCAAGGCCCAGGCTTCTGGGTTCAAGGGGTGGTGGGATAATCATGCCACTTCGTCCTCTTGCTATGGGAAAACCAAGGAGATACTACATGTGAAAATGCCTTAAAAACCTCAAACCAGGCCGGGCGCAGTGCCTCACGCCTGTAATCCCAGCACTTTGTGAGGCTGAGGCAGGCAGATCACGAGGTCAGGAAATCAAGACCATCCTGGCCAACATGGTGACACTCCATCTCTACTAAAATACAAAAAATTAGCCAGGGGTGGTGGCATGCGCCTGTCGTCCCAGCTACTTGGGAGGCTGAGGCAGGGGAATCACTTGAACCTGGGAGGCGGAGGTTGAAGTGAGCCAAGATCACGCCACTGCACTCCAGCCTGGCGACAGAGCAAGACTCTGTCTAAAAAAAAAACAAAAAACAAAAAAAACCCCACAAACCTCAAACCTTCAGTGGCAGGAGAGTTTACTTTTTCCCTGAAGGGTCAAAGTTCAGCCTCTGCTATGGATGGAAGGTGAGACTGGCTTATGCCATAATCAGTGTCACTAAAACATCATCATCATCGTCATCATTATCATCATCATCACTATTTTTAGTAACTGTGACCAGCAATGAACTAGGCACAGGCTTCGTAGTATCTCTAATCTGCACACAGCTGTGCAGCTGAAGTGTCATTGTTAGCCCCACTTTACTGATAAGAAAAAGGGCCCTTGACCAAGGTTATACAGCTAAGTGGCTGAACGAGAACTCAAACCCAGCTTGGTACCCAAAGCCCCGCTCTTTCCACTATCCCATGCAACTTCTGGGCTTAAATCTAACTTCTATCCTAATCATGTTAAATCTACTACATTCCCAGATCACATCAGGTGCTTACTGTGGTCCAGGAATCCCCATGGTTTAGAGTTATGTGCAATATCTTAATATAATAAAAATGGATGGCCACACACAGCTGCCAAAATTAGAGAAAAATTCTCTTTCCATGTGAGACACTGGTGCCCCGCAAAGACTCAGACCTGCATTGACGCAGCACTTGGTTTCTCTCCTCTCTGCCTCCTTCAG
Seq C2 exon
GGCCCATCTGGTTAGACAATCTCCACTGTACTGGCAACGAGGCGACCCTTGCAGCATGCACCTCCAATGGCTGGGGCGTCACTGACTGCAAGCACACGGAGGATGTCGGTGTGGTGTGCAGCGACAAAAGGATTCCTGGGTTCAAATTTGACAATTCGTTGATCAACCAGATAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134013-LOXL2:NM_002318:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.009 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0053013=SRCR=PU(58.2=47.9)
A:
NA
C2:
PF0053013=SRCR=PD(40.8=67.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)