HsaINT0095576 @ hg38
Intron Retention
Gene
ENSG00000134013 | LOXL2
Description
lysyl oxidase like 2 [Source:HGNC Symbol;Acc:HGNC:6666]
Coordinates
chr8:23316949-23320052:-
Coord C1 exon
chr8:23319885-23320052
Coord A exon
chr8:23317115-23319884
Coord C2 exon
chr8:23316949-23317114
Length
2770 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
3' ss Seq
TGTTTTGTTGGTTCTTCCAGGAG
3' ss Score
9.35
Exon sequences
Seq C1 exon
CTGCGCCTGAACGGCGGCCGCAATCCCTACGAGGGCCGAGTGGAGGTGCTGGTGGAGAGAAACGGGTCCCTTGTGTGGGGGATGGTGTGTGGCCAAAACTGGGGCATCGTGGAGGCCATGGTGGTCTGCCGCCAGCTGGGCCTGGGATTCGCCAGCAACGCCTTCCAG
Seq A exon
GTGAGAAGCCCCGGCCTCAGACCCCGCATTCACCCCCCATGCAGTCTGACCACACTGTCTTCAGTCAGCCCCCCTCTCCCACGTACCCTCCCTAGCCGTGCAGGCAGGACAGAGCAAGTTGCCCTGGACCCAGAGGCAGGGAGCCTCGCTCTGGCCACAGCGCTGCTCCTTACAGGCCTGAGTCCTCGGGCAGGTCGCTCCCATCTCTGCCTCTATTTCTCGGCTGCAGAACGAGGGGCTGGGCTCTGCTTTTCATGGTCCACTCCTGCTCTGCACACTGGGGTTCACCCTGGGCTCAAGACTGATCCTGGGGGTTCCTGATGTGCCTTGTGCAGAAGGAACCAACTCAGTCCTTCGGGGAGGTGGTGACCCCCAGCCCAAGGCTCAACCCCCGCTAAACGCCTTAGCTTGCTCCCTTGAAACCCGCTCTGGTCTGAACACGTTTCCCCGCTGGCATCTGTGCCTAATGCATTCTCCCATTGACACGCTAGGGAATCTCCAAGCCTTGTCACATCAGCTGCACTTCCTCCCACTGCCCCCTCTCCAAAGAGAGTGACTCAGCTGAGAACAGCTGAGCTCTGGTCCTAGTTCCCACCCTCCCGCCCCCATCACAGAGCAGCAACAAAATAGGAGGCTCTGGGTCTAATCCCGACGCATTCCCACCAGCTGGCTGTGTAATGGTCTGAGGCAAAGCAGCCACCCTTCCCTGCCTCAGTTGTCCTCCCTGTGACATGGAATGAATAATCCCAAGACCTCAGTATCCTGGTTGTAAACACTTCCATTAAGCAGCTTACATAACGGGAAGATGCTTGGAGACCCTGCTCTTGTGTTGTTAACCCTGACTCCAGCTCTCCTTCCCCAGTGGTCCTTCTTGGGGCCTAAGAAAGGGGTTTAGGGAGAGAAGAGGAGAATTCCTGCATCCTTACTGAGCCTGACTGTCTCCCATGGGCTGGGTGGGTCCCAGGTTGCTCCAATGGGAGGTCCTGAGCCCTGAGCAGAAGCTGCCTGGGATCCCCTGCCCTGTGGCTCCTCATTCCGGCATCCAGAAGAGACAGGCCTTTAAAATAGCTGCTTACGCCCTCTGGGAGCTTGGCCTCCCCAGGCAACGCAGTGTTTCTGCTAATATTGTTTATGACAAGCCAGGGCACTCTCTAAATCTCCAAGGAGAGTGGAAAAACGGTGCCACATTTCAAGGGAGTCTTCAACCAGATATTTTTCTTCCCAGTCAGCTCATTCCTAAGACACCTGGGCCTCAGCTGGGGTCTTGAAATAGGCCTGGGACTGACATTTGTACCAAATCTGCCACTGATTACAAGCCCCATCCCTTCTCAAGTCCTCATTTTTTTCATCTGGAGGATGGAGGTGGGTATTGGTCAAGTTCTCTAGAGAAACAAAACCAGTAGGTTGTATGAATGTGTATTTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCTATCAACCAATAGGATGTATGAATGTGTGTTTATATATGTGTATGTATATCTCTCACACACACAGCATGAAGAAAGATATTTCTTTTAAGGAATTGGCTCATCCAATTATGGGGCTGGCAGGTCTGAAGTCTGCAGAGTAGACCAGCCGGCTGGAAGCATTGATGTTGCAGCTAGAGTCTGAAGTCAGTCTGTGGTCAGAATGGCTTCTTCCTTGGGAGGCCTCAGGTTTTTTGGGTTTTTTTTTTTTTTACCCCTTAAGATCCTCAACCGATTGGATAAGAATTGCCCATATTATGGAGGGTAATCTGCCTTACTCAAAGTCTACTGATTAAAATGTTAATCTCATCTAAAAACAGCCTCACGTAAGCATCTAGAATAGTGTTTGACCAAATATCTGGGTACTGTGGCTTAGCCAAGTTGACACGTAAAATGAACCATCACAGGAGAGTTTAGATGAGATACTAATACTTCCAAGGCCCTTCCTATCCTGATGGTCTGTCTCTGACGATCCCGAGAAGACCTCCCTGAGCTCTAATCCTGCCTCAGCCTCCAAGCCCGAGAGACCTGAGGAACACAGCACCTGTGTTCTCATCCCGTTTCTGTACCTGACGATCCCAATTCTGCTCCTCATTTTTCTCTGCTGGAAACTTCTCTGAAGTGTGAGAGTAAATCCTAACAGTATTTCGAAGGCCCATAGAGCAAAGGGGCCAAATAAATCCCAGCATCCTAAGCCTCGGATCTCCTCAGCTTCTGTGCAGAACTACTCTATTAATTGCTCTTTAAACTGGGGAAAAGTCTAAATTCAGAAGTTCGTCTTTATAACATGTCTAATGATTGACCTATGCAAATAGATTTCTTCTTCTCTCCCACCACTTCCAATCAACCAGTAACATCTTCCTGGAGCACTGTGTTGAGAAGGATTCTGAGATCCTATTCGGGCTTAGAGGAGAGAGTGCTGTGATTGATTAGCAATGTCTGCCCTGGATCAGGACTGGGGAGTGGGCAACCTGAGTTGTGTGCACCTGCCATTCCTGACACACAGCCTTGCAGTGTCTGACCACAACCTTAGCTCTACTTCCCTGAGGGAGAGAGTGACAGAGTCCAAGTGCTACACTCAGGAGACCTGGATTCCCACTCACTCTGCCACCAACTAACTGCACAGCTTGGATAGGTGACCCTCCGTGCTGTTTCGATCTGAAAAATGGGATCATGAAACATTGGGATTTTTGTGAGGCTGCAAGTTGATAGGATATGAGAAAGTGACAGTTTGAGATGATGTACCCACCATTTGTTTTGTTGGTTCTTCCAG
Seq C2 exon
GAGACCTGGTATTGGCACGGAGATGTCAACAGCAACAAAGTGGTCATGAGTGGAGTGAAGTGCTCGGGAACGGAGCTGTCCCTGGCGCACTGCCGCCACGACGGGGAGGACGTGGCCTGCCCCCAGGGCGGAGTGCAGTACGGGGCCGGAGTTGCCTGCTCAGAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134013:ENST00000389131:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0053013=SRCR=PU(48.6=92.9)
A:
NA
C2:
PF0053013=SRCR=PD(49.5=94.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development