HsaINT0096409 @ hg38
Intron Retention
Gene
ENSG00000081479 | LRP2
Description
LDL receptor related protein 2 [Source:HGNC Symbol;Acc:HGNC:6694]
Coordinates
chr2:169216253-169220563:-
Coord C1 exon
chr2:169220454-169220563
Coord A exon
chr2:169216431-169220453
Coord C2 exon
chr2:169216253-169216430
Length
4023 bp
Sequences
Splice sites
5' ss Seq
TGGGTGAGT
5' ss Score
8.73
3' ss Seq
GGTGTTTTTCATGGTTGTAGGAA
3' ss Score
6.78
Exon sequences
Seq C1 exon
GTTTTGACACTCCACGGAGATATCAGATACAGAAAAACATTGATTGCCAATGATGGGACAGCTCTTGGAGTTGGCTTTCCAATTGGCATAACTGTTGATCCTGCTCGTGG
Seq A exon
GTGAGTATTCATAAATGGCACGTGTCTTCCATGCAGCATTGTTCTTGTTAATGTCAGGGTCTGACAAAATGGAAGATTTCAAATTTAGGACATCTTCTGATTTCATATGTCAACATTTGAAAAATAATAGATCTCAGTGAGAAAGAGAAATAGCTCTGACCTATATTTAATGTGCAGGATATTGTTTGTATTTTGTCCTATGGTCTTCAAATGAACAACACTGGATTTAAAATTAATTCCAAACAAGCAAGAATTTTAGGAATTTTAAAATAGCATTATAAGAATTGACAATATATTCTGACTTTGAAAGGACACGGAAAGCTCTAAGGGATTATGTAACATTTGCAATAGAGCTTGCAGGATGAGAAGCCTTCTAGTAGGTGGAGAATGGGTTGCAACCAGGCAGTGACTCTTGAGGCCAAGGGATCCATGAAGGCACAGAAGTATGGCGGCACTTAGCAGGATTGTGGGGAGAGCCGGAACCAGAGGCTTAGAGTAGGGAGCTGTTGACCACATGGGAGATACAACAGATAAGGTCATTTGGGGACAAATCAAGGAGGGCCTTTAATATCATGCTAAGAAGTTGAACTTTATTCTTTTGAGTGATAAGGAGCAAGTAGGGATTTTTTTTAAAAAATTTCAACTTTTATTTTAGTTATAGGGGGCACATGTGCAGGTTTGTTACATGGGTATATTGTACCCAGATAGTGAGCATAGTACCCAATAGTTAGTTTTTCAACCCATGCCCTCCTCCCTTCCTCCCCTCTCTAGTAGTCCACAGTGTCTGTTGTTCCCATGTGTATGTCCATGTGTGCTCAATGTTTAGCTCCCACTTATAAGTCAGAACATGTGGTATTTGGTTTTCTCTTCCTAGCAAGGAATCCTGAGGAAGGGAGTGAAAGAACCAAATTTGTGTTTTAGAAAAATTGGTCAGGATTGATGTGGAGAGAGGCCAGGGCCAGGGAGACCAGTTAGGAGAAAATGGTCTTAATGGATGTAGGCTGGAGTCCTCCGGTCTGTTTGATTGGCTATTTCATTCTGTTGATCTACTATACCATATTATAAACCAGAATAACAAATTGTAAAATATGAACACTGATTTTTTTTTTAAAGAGATTGTAGCATCATTCCAAGTGGATTTTGGCTTAATGTTTGAAAGTTATCAGATTCTTAGGCCTAGAAGGGCACTGAAGAAGTAATTTGTATTAGCGCTCTGTTTCAAATAAGGATGACATGGAAACCAAATCCAATTTTTAAAGGGCACAAGAAGCAAACATTCTATTCTGTGCCTGCTGGCTTGTACTAGTTTTCAGTTATTCTTTCTAGAAGAAGGACTGTCTTAGGTTCGAAATTCTACTTTTGAAACTCAGGCTCACTCATTATTTGTTTTTCGTTTATCAGACATTTCTGCATTGTGTACCTTTGTTGGGTGGTGTGTTAGTTAAGATAGCTAACTGTTGAAGCAAATAAACTCCTAAATATGTAATGGCTCAAAGAAAATAGAAATTTTTTTGTCTTTTATATGGGCAGTGGGGTTTGGGCAGAAGATGGGAGGAAGCTCTACTCTACGTAGTCATTCAGGACCCAGGCTGATGGATGCTCTGCCATCTTCAGTAGGAGGCTTCCTAGGTCATTCTGAGTATCAAGATCTTTCGAGCAGTAAAGGAAAGAACGTTCAGAAATTTGCTGGGAGGTTTTTATGAGCCAGGCCTACAAGTAGTGCACGCCACTTCTGCTCACACTCCTTAAGCTAGAATTGGGTCACATGGCCACAGCTAACTGCACGGAAGGACATGCAGTCCACCTATTTACCCAGAGAGAAGAGGAAGACATTAATTTTGGCAAGTGGAGGCAGTCTCTTTCATGGGGCCATGGTGGGGAGTTCAGAGGGTGGATACAAAGATTAAAGACCTAATTTGCAACCTTAAGGATTTATGGCTTAGTAAGGAGGATAAGGCCTGTGTATAAATAACAATAACCCAGATTCATATAAGATTAAGAGCCACAAGAGAGGCTAAAAAAATTGGGATGATAGTGCTATAAAGAGGTGACATTTCAGCTTGGTGGAAGAGATATCATTTGGACTGGATCTTAAAGCATACCTAGAATTTCACTGGGCAGAGCTAGCTTTTAAGATATATCAGGCGATATGAAGGATGGAAGGTCAAGAGCAAAGGGACAGAAAATTGAGGGTTTGTTCAAGTGACTAAGAGCAACCCAGTTGGGTTGGGAGACAATTAGAAGAGCTTAGAATTTTGTCAGAGGACATAGGAGGAGAAACAAGACAGAGACTTGAGGATCTAATATCTTGGATTCTCAGTGAAGAGAAAGTCTTGATAAAGTTGTGATAAATGTTATTGAACCAGTTGTTGCAGAAAAATATCTTTGTGGATGATCACTAATAAAGAGCTGAGGCAGTTACAGGGTCTCTGATGATATTCAAGAGAGGATGTTGAATAGAGATAGTAGAAGTTAAAAGAATGGAAGGAGGATGAGGAAATGTGAATACTCTTTTAAGAATTTTGTATTGGAAAGTTAGAGAAAGATAAACTTGTAGGTCAAAATGTAACAGGAAAATGTCTTTCAGAATAGAGAAACCTGAGTGTATTCTTTAGCAGCAGATGAAAGATCAAGGATGAAGAAATAATTGATTGAGAGTGAAAGTTATGGGGAAGGAATTCGAAATTTATGAAGTAGAATGACTTGAAATAGTCAATATGCGGAACATGATATAAAGTCTGCTAGGGATGAGAATCCTCAGCTTAGATTAGGGAACTTAGATTTTTAGTGAATTCAGAATTCACGAAAGTTTTGTGCTATGTCCAGGAAACTCTTGGTACCCTGAAATGGGAGAGGAGAAAGAAAAAAAAGGGCAGAAACCCAGGGTTGGAGATTAGCTTAGACACAATGGGAACCCAAAAGAATAAATAAGAATATTGTTGAAATGGTTACATATGATGTCCAGGTGTAGAAGAACTGGAGGGTTGGGAGCTCAGGCAGGGCTTAAGGGCAAAGAACAAGTTTAATAGGAAAAGTTAAAGCAAGGAAGAAATGAGAGGTTTTGGTCGAAGCAGAGCATTTCAGAGTTTGAGAACTTAGAGGCGGAGAAGTTTAGAGTTGAAGATGAAATTCAAAGGACGGGTATATTGATTTGGTGGTGGAAGAGGTAGGTGAATAAAGACTATTTAAATGAAGGGGTTTAAGGACTTTTCAGAAAAGAATGTAGGAGAATTGTCTGTTGAAGATATAGAAGGAGGTGCAATCAAAAGGAATTAAAAGTTGGGTTCAAGTCTAGAACTTACATCTTCAGTGGAAATGGAAAACAGCCCTTAATATATTTTAATACATTTTCATATATCATGGATTTGGCAATGCTGTGTGGTAATTATGGTTCATGTGTACCTGATCGCTGTGAAATAGAAAGAAAAAAGAAGTCTTCCTTACCCCATAACAGCATGATAATGAGATTCCACTCTCACAGAAAAGTGTTACTCATTATTTCTCCTATTTTCTGTGTCAGTTTTCAAAATTCTTTGCATTTTTCATCACAGAAATCAGGTTAGGTAATTAAGTAGCCGGTCTTGTGGTAGATGGTGATTTGGGGAATAATTAAATGAGGCCTGGTAAGTGATCAGGGAGTGTACTTGGCAGCTTTTTATATTAGCTTTGGCCTTCACTATGTACTGAAGATGGAGGGATTATTGATGTAGGTTTCTTCCTTGTCATAAGCTTCCCACACACCTGACCATGCTAAAAGTTCAGCTGCCAGTGGGATACCCTAGCTTCTTATTCCAGACACCATTTTAAGTGGCCTCTACTCCAGTTATAGCTAGGAAATATACCGACATTGGTAGAACACTGGTGAAGTACCCCTCCACGTTGTATGCAACGAGATATTGATTTTCAGCCTTTGCCCATTGTATTGTGAGCATCTTGAGGACAAGTAATACACATTGTCATTTATGTCACTGACTCAAATCCACCTTCTGTTTTGTTACATGCTGGTGTTTTTCATGGTTGTAG
Seq C2 exon
GAAGCTGTACTGGTCAGACCAAGGAACTGACAGTGGGGTTCCTGCCAAGATCGCCAGTGCTAACATGGATGGCACATCTGTGAAAACTCTCTTTACTGGGAACCTCGAACACCTGGAGTGTGTCACTCTTGACATCGAAGAGCAGAAACTCTACTGGGCAGTCACTGGAAGAGGAGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000081479:ENST00000263816:34
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.033
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PU(0.1=0.0)
A:
NA
C2:
PF0005812=Ldl_recept_b=WD(100=76.7),PF0005812=Ldl_recept_b=PU(28.2=18.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development