HsaINT0096528 @ hg38
Intron Retention
Gene
ENSG00000162337 | LRP5
Description
LDL receptor related protein 5 [Source:HGNC Symbol;Acc:HGNC:6697]
Coordinates
chr11:68386316-68390052:+
Coord C1 exon
chr11:68386316-68386712
Coord A exon
chr11:68386713-68389880
Coord C2 exon
chr11:68389881-68390052
Length
3168 bp
Sequences
Splice sites
5' ss Seq
GGGGTAAGA
5' ss Score
7.83
3' ss Seq
GACTTCTGCTTCTTCTCCAGCCT
3' ss Score
7.15
Exon sequences
Seq C1 exon
GAGCCGAGGAGGTGCTGCTGCTGGCCCGGCGGACGGACCTACGGAGGATCTCGCTGGACACGCCGGACTTCACCGACATCGTGCTGCAGGTGGACGACATCCGGCACGCCATTGCCATCGACTACGACCCGCTAGAGGGCTATGTCTACTGGACAGATGACGAGGTGCGGGCCATCCGCAGGGCGTACCTGGACGGGTCTGGGGCGCAGACGCTGGTCAACACCGAGATCAACGACCCCGATGGCATCGCGGTCGACTGGGTGGCCCGAAACCTCTACTGGACCGACACGGGCACGGACCGCATCGAGGTGACGCGCCTCAACGGCACCTCCCGCAAGATCCTGGTGTCGGAGGACCTGGACGAGCCCCGAGCCATCGCACTGCACCCCGTGATGGG
Seq A exon
GTAAGACGGGCGGGGGCTGGGGCCTGGAGCCAGGGCCAGGCCAAGCACAGGCGAGAGGGAGATTGACCTGGACCTGTCATTCTGGGACACTGTCTTGCATCAGAACCCGGAGGAGGGCTTGTTAAAACACCGGCAGCTGGGCCCCACCCCCAGAGCGGTGATTCAGGAGCTCCAGGGCGGGGCTGAAGACTTGGGTTTCTAACAAGCACCCCAGTGGTCCGGTGCTGCTGCTGGGTCCATGCGTAGAAAGCCCTGGAGACCTGGAGGGAGCCCTTTGTTCCCCTGGCTTCAGTTTCCTCATCTGTAGAATGGAACGGTCCATCTGGGTGATTTCCAGGATGACAGTAGTGACAGTAAGGGCAGCCTCTGTGACACTGACCACAGTACAGGCCAGGCCTCTTTTTTTCTTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCGCCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTACAACCTCTGCCTCCTGGGCTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGCCTGCCACTGTGCTTGGCTAATGTTTGTATTTTTGGTAGAGATGGGGTTTCACCGTCTTGGCCAGGCTGGTCGCAAACTCCTGACCTCAGGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGCCCGGTCAGGCCAGGCCTCTTTTGAACACTTTGCACACCATGGGTCTTTTCATCCAGGGGGGTAGGTACAGTTGTACAGTTGAGGACACTGAAGCCCAGAGAGGCTCAGGGACTTGCCCAGGGTCACACAGCAGGATGTGGCAGGTGTGGGGCTGGGCCTGGCAGCGTGGCTCCAGCTTTCCAGCATAGAAATCTGTGAAAGCAGATAGTTTGTCGGTCGGTAGGGGAGACTTTCTGAGACCCGCCCCAGCGGCTCAGAGGGTAGTAGCCAGGGGCCTTCCTGGGGGCTCATAACCCAGAACACTGAATGGGAAAACCCTGATGGAGGAGGCGCAGTGGAGCTGTGGGTGCCGATGGGAAGTCCCAGAGGAGCTGGGAGGTCAGTAGCGGTGCTGCCCTCTGTGGAGCACTTAGTGGGCACCAGGTGTGTTTCCAGGTTCATGGCCCTGGGACCTGAAGCTCAGAAGGTGAAGTAACTTGCCCAGGGCACCCGTCGGGCAGCGGCGGGCAGAGGATTTGTGGGCTGTGGAGCCTGTGCTCGTGGCCCAGCCCTGGGGGTTGTGAGTGTGCTGGCCGGGGAGCTTTTCCTGCAAGTGGACTGGTGTCTAGGAGCCAGCATGTCAGGCAGCAGGCAGCGGGAGTGCAGCAGGCAGCGGGAGCACAGCAGGCAGAGGGCGGGGCTCGAGCAGCCATCCGTGGACCCTGGGGCACGGAGGCATGTGGGAGAGGGCTGCTCCATGGCAGTGGCTGAAGGGCTGGGTTGTGCCCCGAGGAGGGTGGATGAGGGTAAGAAGTGGGGTCCCCAGGGGCTTTAGCAAGAGGAGGCCCAGGAACTGGTTGCCAGCTACAGTGAAGGGAACACGGCCCTGAGGTCAGGAGCTTGGTCAAGTCACTGTCTACATGGGCCTCGGTGTCCTCATCTGTGAAAAAGGAAGGGATGGGGAAGCTGACTCCAAGGCCCCTCCTAGCCCTGGTTTCATGAGTCTGAGGATCCCAGGGACATGGGCTTGGCAGTCTGACCTGTGAGGTCGTGGGGTCCAGGGAGGGGCACCGAGCTGGAAGCGGGAGGCAGAGGGGCTGGCCGGCTGGGTCAGACACAGCTGAAGCAGAGGCTGTGACTTGGGGCCTCAGAACCTTCACCCCTGAGCTGCCACCCCAGGATCTGGGTTCCCTCCTTGGGGGGCCCCAGGGAACAAGTCACCTGTCCTTTGCATAGGGGAGCCCTTCAGCTATGTGCAGAAGGTTCTGCTCTGCCCCTTCCTCCCTCTAGGTGCTCAGCTCCTCCAGCCCACTAGTCAGATGTGAGGCTGCCCCAGACCCTGGGCAGGGTCATTTCTGTCCACTGACCTTTGGGATGGGAGATGAGCTCTTGGCCCCTGAGAGTCCAAGGGCTGGTGTGGTGAAACCCGCACAGGGTGGAAGTGGGCATCCCTGTCCCAGGGGAGCCCCCAGGGACTCTGGTCACTGGGCTTGCCGCTGGCATGCTCAGTCCTCCAGCACTTACTGACACCAGCATCTACTGACACCAACATTTACAAACACCGACATTGACCGACACCGACATTTACCGACACTGACATTTACCAACACTGTTTACCAACACTGACATCTACTGACACTGGCATCTACCAACACTGACATTTACCGACACTGACATTTACCAACACTATTTACCAACACTGACATCTACTGACATTGGCATCTACCAACACCAACATTTACCGACACCAACATTTACCAACACTGAAATTTACCGACACCGACATTTACCGACACTGATATTTACCAACACTGACATCTACTGACGCTGGCATCTACTGACACCGATGCCAGCATCTACCAACACCGACATTTACCAACACTGACATTTACCAACACTGACATTTACCGACATTGACATTTACTGACACTGACATCTACTGACACTGGCATCTACTGACACTGATGTTTACCGACACTAGCATCTACTGACACTGACATTTACCAACACCAGCATCTACCAACACCGACATTTACCAACACTGACATTTACTGACACTGATATCTACTGACACTGGCATCTACTGACACCAACATTTACCAACACCAGCATCTACCAACACCGACATTTACCAACACCAGCATTTACCAACACCGATGTTTACCAACGCCGACGTTTACCGACGCCAGCATCTACCAACACTGACATTTACCGACACCGACATTTACCGACACTGACATTTACTGACACTGACATCTACTGATACTGGCATCTACCGACACTGATATTTACCAACGCCAGCATCTACTGACACTGATGTTTACCAACACCGACATTTACGAGCACCGACATTTACTGACACCAATATTTACTGACATCAACATTTAGCCATGTGATGGGGGCCGGCTTGGGGGCAGGCCTTGCTCTTGGCACTGGGGATGCTGCAGAGACCAGACAGACTCATGGGGTCATGGACTTCTGCTTCTTCTCCAG
Seq C2 exon
CCTCATGTACTGGACAGACTGGGGAGAGAACCCTAAAATCGAGTGTGCCAACTTGGATGGGCAGGAGCGGCGTGTGCTGGTCAATGCCTCCCTCGGGTGGCCCAACGGCCTGGCCCTGGACCTGCAGGAGGGGAAGCTCTACTGGGGAGACGCCAAGACAGACAAGATCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162337:ENST00000294304:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=30.8),PF0005812=Ldl_recept_b=WD(100=30.8),PF0005812=Ldl_recept_b=PU(0.1=0.0)
A:
NA
C2:
PF0005812=Ldl_recept_b=WD(100=72.4),PF0005812=Ldl_recept_b=PU(33.3=22.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development