HsaINT0097536 @ hg38
Intron Retention
Gene
ENSG00000119681 | LTBP2
Description
latent transforming growth factor beta binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6715]
Coordinates
chr14:74528958-74532548:-
Coord C1 exon
chr14:74532426-74532548
Coord A exon
chr14:74529123-74532425
Coord C2 exon
chr14:74528958-74529122
Length
3303 bp
Sequences
Splice sites
5' ss Seq
TGTGTGAGT
5' ss Score
5.84
3' ss Seq
ACGTGCTGTGTCTGTTGCAGCGG
3' ss Score
11.18
Exon sequences
Seq C1 exon
ATATCAACGAGTGCTTGACCCTGGGCCTGTGCAAGGACGCGGAGTGTGTGAATACCAGGGGCAGCTACCTGTGCACATGCAGACCTGGCCTCATGCTGGATCCATCGCGGAGCCGCTGTGTGT
Seq A exon
GTGAGTGCTGGCAGGGATGGGGTGGGGGTGGACAGTGGGAGACAAGATGGGACACTTCAGGTCCACAGGCCAGGCCCAGGGCAGCAATTTTCCCCAGACCTGATCACGCCATGCTCAGGGCCTGTGTCGGCTATTCAACCTGGAGTTGGGCCCAATGTGAAAAACCTGATCAGCCCATCCTGCTGGAACAGAGATGGTTACTACTTCACTTTTTACACTAGGCATTTTTTCCGGGCCTTTGCAGTTTGGAATTCGTCTTTTCTATTTCTTATTTTTTTTCCTTTCTAATCATTTCTGTTCCATGTGTAGCCTCGTTTTCTTTGGTGGCGGGAGGTGGTGGGGGTGGCCTCTGCTCTGATGTCTGGCTGAGCCTTGGCTGCTGAGTGACCTTTCCAGAAGGGCTGTCCATAGCATTCATGGAGCTGCTGCCCGACCCGAGGGCCTTTCCACAATCCTGTGGCCCCTTGTGGTTCTGAAGTTTCTCCTTATCTGTGAACACATAGTGGGCATTAGCATTGTGTCCAGGTATGTACATGCATGTATGCCAGGCAGCCCTGTTTCCAGAGACCTCTGTGGTTTCCAGGGTGAGAGGCCCAGGCTGGCAGCAGCCCCCAATGGCAGAACTGACACCACAGCCCAGATAGGGCTTTCCCTGGGCCGGGAGGCCTGACCAGAGCTGAATAAAACCAGTCCCAACTGGCCTCTGGGAGGCAGCAGCCGAGGTTGGATGGGCCACGCCCAGCTCAGCAGAGCTCCCTGCAACCGGCCAAGCCCTCAGTCTGCAAACTTTCTGGTACTGGGTTTGGGAGGGCCATGGGATTGGACAAGACTCCAGTGCCACCCAGAGGCTGAACCCAGTGGCTCTAGGGAGAGAAGACAGCAAGAGCTATAGGAGGGGGGTGCCCAGAGAGTGAGGGGCCCAGAGTGGGGAGAACATGTCAGACCGCTCTCAAGAAACCTTCATGGTGGCAGTGGCAGGTGATCAAGGCCTTGAGAGGCTTACACCCTTCCTTCTACTCCACATCACTTAAGATCCCTTTACCAGAGAGGTGTGTTTGACATCCAAGGTGACTTATTTATTAGTCCCAGAAAGAGACCCTTAATACAGGGAAGCAGAGATGGCTCTCGAGTGTCCTTTTTTCCCTCTCTGTCCCTGGTGTTACTCCCTCCAGCCTCCTACAGTGATTCACCTCCCTGTAAGTGGGAGGGGTGGCACGAAGTTTCTCTTCCCTTTGTTTCTGAGTTCTGCCTCCTTCCCTCCCTGCCGCCTGACCAGGTCCAGTGGGGCAGTCTACAGGGCTGCCCCAGCCTCCTGATATTCCCACCTGGGTCATCTCCACCCTGGGGTTCAAAGGGACAGAGCCCTTCCTTACAGTGTCCCAATGGAAGTGGCTGCTAGAAGCAGAGTTTGCACCTGGAGATCCAGGGCTCACAGACGGCTGATGATTTACCTGTGGCGGGCACATGACCTTTAACAAGCCACTCTCACACACCTCACTCTATTTAATCTCCACGACAATACCACGAAGAAAGTTTATTAATCGGGAGTCTTTGGATTGCAAGTGACAGAAACCAAACTCAAACTGCCTTAAGCAAAAAAGAATTCGCTGGGGCTGGGCCCCGTGCCTCTCACCTGTAATCCAAGCACTTTGGGAGGCTGAGGCAGGTGGACCACTTGAGTTCAGGAGTTTAAAACCAGCCTAGGCAACATGGTGAGACCCTGTCTTTACAAAAAATTAAAAATTAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTTGAGAGGCTGAAGTGGAAGGATGGCTTGAGCCCCAGAGGCAAAGGTTGCAGTGAGCCGAGATCGTGCCACTATACTGCAGCCTGGGCAATAGACAAGACTCTTCTCAAGAAAAACCAAAAGCATTGGTTCACACAACTAGGAAGTGCAGACGTGGTATGGCCTCAGGCTGGCTGACCTAGGCAGCCACAGTGTCTGCAGGGCATGTCCTGCTCTTTCCTCTGTGTGAGTTTCATGGTTCCTTCAAAGGTGGTCACCAGATGCTCTAGGCCTACACCCTCTCAGCCTTGCAAACTCAATAAAAAATGAGCCCCTTTTCCCCAATAACCCAGGAATAATAGTCTCAAAGCTGATTATCATTGGGCCTCCTTGGTTAAGTGCCCATCCCTGACCCAATCACTGTAACCAGGGGTATGGACCACAAGCCTTCAGCCAGAAAGGCGTCAGCCTCCACTCCAGTCATATGGACCAAGGGTGGGAAAGGGTGGTTCCTGTAGGAGAACCAGAGTGATGATACGAGAATATGGTGCATAGACTCTGGGCAGGCAGAAATACAGGTGTCCCCTGCGATGGAATCATCATTCTCATCTTCATTTTACACGTGAAGAAGCTAAGGCCCAGGGAGGTCTGTAGTTCATGGTGGAGCAGGGATTTGAACTTGGTCTGCTGCGTCCTGGGCCTGACCAGCACTTCCCCAGAATCATTCATTCCTAAACTTTGATTGATGTCCTCTTCAGCCCACTCTCCTCCTCTTAGAATCCAGTCAGCCCTCTACGGATTCCAGACTCTTCCAACCTGGCATGGCCTCCTCGTCTTCCATTGAGATAACATACAGAAACTATTCTTTAATATTTATTTTCAAAGTACAAGAAAGGAGATAAGGGTGGTGGCATTGCTATGACCTAAGCCCAGCATAGCTCAAACTCACAGTGACCCTCAGTATTTTGATTGGCTGGTTGATTCTGTGTTTGATTGGTTCATTGACCTAGCCATCCACGCATAGCTTCAACAAGCATTACTAAGCATTTGCATGCACCAGGCACTATGGGAGGTGCCTGGGTGACAGAGATGACCCAAGATAGGGTCCCTGTCCTCCGAGCTCCCCATCCGGCCTTAGCTCCTTACCTTGCCTCATCTTCCCAGGGAGGCTGTGGTCCTCAGGACATACTGCTGCCCGCTCAACCCTAGGGACACGTGGGGCCTTCAGTAAACACTTCTAAACTCGGCACTGGAGACAAGCAGCTGCATCCTCATTCCCTGCTCTCAGGTTCTCCACATGCAGGTGGGGAGTCACGAGTCTCATCAAGCACACAACATGGGCAGGTGCTGAAACATTCCACTACGCCTCTTCCTCCTAAAGTTCTTGTGAGCATTTGCAGGGCTCCAAACTTCCCAACTGAGATATGGGCCAGGCCAGTCTGAGTGCATGTGGCCAGCCACACCTCCATCCACTGCCCTCCCAGCTGCGCATTCCCCTCCCACTGGCCACCTGCCCACCTCCACGTGCTGTGTCTGTTGCAG
Seq C2 exon
CGGACAAGGCAATCTCCATGCTGCAGGGACTGTGCTACCGGTCGCTGGGGCCCGGCACCTGCACCCTGCCTTTGGCCCAGCGGATCACCAAGCAGATATGCTGCTGCAGCCGCGTGGGCAAAGCATGGGGCAGCGAGTGTGAGAAATGCCCTCTGCCTGGCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119681:ENST00000261978:10
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=95.2)
A:
NA
C2:
PF0068312=TB=PU(86.0=66.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development