HsaINT0097559 @ hg38
Intron Retention
Gene
ENSG00000119681 | LTBP2
Description
latent transforming growth factor beta binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6715]
Coordinates
chr14:74503469-74504054:-
Coord C1 exon
chr14:74503926-74504054
Coord A exon
chr14:74503607-74503925
Coord C2 exon
chr14:74503469-74503606
Length
319 bp
Sequences
Splice sites
5' ss Seq
AGGGTAAGG
5' ss Score
9.16
3' ss Seq
ACCCTTTCCTGCCTCCCCAGATC
3' ss Score
11.25
Exon sequences
Seq C1 exon
ATGCGGATGAGTGTGTGATATTCGGGCCTGGTCTCTGCCCGAACGGCCGGTGCCTCAACACCGTGCCTGGTTATGTCTGCCTGTGCAATCCCGGCTTCCACTACGATGCTTCCCACAAGAAGTGTGAGG
Seq A exon
GTAAGGACACACATGATCCCTGCCCCCACCCCAGGCCCACAGCTGAATAATGGCCCACCCAGCCCCTGCCAGCCAGTCCCATTATTGCTGAGAGTCCCCCTTCCTAGGGAGGCCGCCCACTGCAGCAGGCTGGTCCCAGGTGAAGGAGCTGTGGGCTGTCAGAGATTGTCCCCAGGAGGGCCTTCCAGGCTGGGCTGGGTTGAGGGGAGGGAGGCAGGGCACTAACTCTTCATTATCAGTGATAGGCAAACACCCTTCCCTGAGGGTGGTTGGTGGAAAGGCCACCTTGGCAATGCCCCACCCTTTCCTGCCTCCCCAG
Seq C2 exon
ATCACGATGAGTGCCAGGACCTGGCCTGTGAGAATGGCGAGTGCGTCAACACGGAGGGCTCCTTCCACTGCTTCTGCAGCCCCCCGCTCACCCTGGACCTCAGCCAGCAGCGCTGCATGAACAGCACCAGCAGCACGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119681:ENST00000261978:31
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=95.5),PF0764510=EGF_CA=PU(0.1=0.0)
A:
NA
C2:
PF0764510=EGF_CA=WD(100=83.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCGGATGAGTGTGTGATATTCG
R:
TGCTGCTGGTGCTGTTCATG
Band lengths:
263-582
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development