HsaINT0097563 @ hg38
Intron Retention
Gene
ENSG00000119681 | LTBP2
Description
latent transforming growth factor beta binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6715]
Coordinates
chr14:74498170-74501590:-
Coord C1 exon
chr14:74501441-74501590
Coord A exon
chr14:74501030-74501440
Coord C2 exon
chr14:74498170-74501029
Length
411 bp
Sequences
Splice sites
5' ss Seq
TAGGTAAGT
5' ss Score
9.66
3' ss Seq
TCTCCTTTGTTTCCTCTTAGATG
3' ss Score
10.94
Exon sequences
Seq C1 exon
AGCCCCCAGCCGGCTTCGAAGGGCTTCAGGCGGAGGAGTGCGGCATCCTGAACGGCTGTGAGAATGGCCGCTGTGTGCGCGTGCGGGAGGGCTACACCTGTGACTGTTTTGAGGGCTTCCAGCTGGATGCGGCCCACATGGCCTGCGTAG
Seq A exon
GTAAGTGCAGAATTCTGATGGAGGAGTCAGGCTGGCCCACTGCCCACAGAGACGCCTGAACTCAGGAAGGCTGGAAGAGCCACTGCTGCCTCCTAGTGGGGCTGTCTGCATCAGGCTGGAAGGGAAGAAAGCGCCAAAGGAAGGTTTAATTATGTGCTTTAGAAAGCCCCTTCCGTGCAGGTTCCCAGACAAAAGACAAGGACAAGAGAGCACGGTCTTGGGCATGGTATGAGCTTGCTGCCCCCTGCTTTGTCCTTGAGTTGCTTGGTTTTGGGAAGTGACTTCAGCCTCTGGCTGTCACACTTAGGGTTTCACTCTAGGGCAGTGGCCAGGGCTTACTAACCAGAGAGGTGGAGGCAGCCAGCAGAGGCACCTGGGCTCCCTACAGCACTCTCCTTTGTTTCCTCTTAG
Seq C2 exon
ATGTGAATGAGTGTGATGACTTGAACGGGCCTGCTGTGCTCTGTGTCCATGGTTACTGCGAGAACACAGAGGGCTCCTACCGCTGCCACTGCTCCCCGGGATATGTGGCTGAGGCAGGGCCCCCCCACTGCACTGCCAAGGAGTAGCAGTCAGGGGTCAGTGTGGCAACTACCTGGAAATGGCCTCCAGTCACAGGCAGGGGCCTTGAGGATGATTTCCTAGCTGGGAAGACACCGTGACATCAGGCCAGAGGTTTCCAATCAGCCTTGCCTGCTTTCATCTCTCCCAGCTTAGCCTCTGGCTGTAAGCTTCGGTCATTGCCTCCATGCCCTTGCTTGGCTCAAGCACCACCAATCGCTTTAATGCTTCAGCCACCGCATGAGGCCCTGTCCACCACCTTTCCTGGCCTTGCTATGGGATGCTTACCAAAGGATGGCCCTCATCCACCCTCCCAAGCTGTGCGAGCATGCAAGGCCCCATGGCCTCACACTGCAGACACCCCTTTCCAGCCACAATCCACCATCATCCTGACGATCCCACAACTGGGACAGAGGCTACATCTGCCCTAGGGAGGTCCTTCAGAATCTGTGGAGCAAGAAAGGATTTGGGGAAGCTTGGGGACTGACTCCAGAGCCCCCTCCTAAGAACCATCACCACCACTCAGCCAATCTGTTCTGGGCCCTGATTTTGCCACACCTCCATCCTGTAGCCCATTCTCTGACCCCAAGGAGTGGCAGAAGATCCCTTCACTCAGAGAAGCAAGGCTGATATTAGCTTGTTGAATGTAAGAGACACAAATGAAGAAGAACAAAGAGCCTGAGAAAGCAGCAAGAGGACATGATGAAAAATACGTGGAGTTGATGAGAAAGGGGAGCCAAGGCTTTATACGTCTAAAGAAAATATTCAGTAGCTGAATCCGCCCAGTGATAGCCTGTGGGCACCAGCAGCAAGGGCTGCCATGGGATACAGCACCCATCTACAAAGACCTCTATTACATAAACACTGCTTCTTACAGGAAACAAACCTCTTCTGGGATCTCCTTTTGTGAAAACCAGTTTGATGTGCTAAAAGTAAAAAGTCTATTTTCCAGTGTGGTCTTGTTCAGAAGCAGCCAGATTTCCAATGTTGTTTTTCCCCTCCACTCAGAAACCCCTGCCCTTTCCCTTCAGAAAACGATGGCAGGCATTCCTCTGAGTTTACAAGCAGAGACTCACTCCAACCCAAACTAGCTGGGAGTTCAGAACCATGGTGGAATAAAGAAATGTGCATCTGGTCTCTTCTGTTGTTTTTATTTCATATCAGATTAAATTTCTTTACCATGTTGGCTAAGTCTAAATATTAGAGATGAGGCTGTGCCTACTCCCTGGCCAGCTCTGCTGATAGCCTATGATGGGTTCCAATGGGAAATGACTCTTTACTATTAAAAGACAAGGAAAGCTCTGACTTCGTACTTCTCTGATGAATGGCAATGTAAATGAACAAGGCTCCATGTGACTGGAGCATGGAAGTGAATGCTACTTTCTTAATTTAATCTGCCCTGTCCTACCTGCTCCTCTGATTGTTAGCCATCACATAACTTATTGAATGCTTGCCATGTGCCAGGCACTGTGCTGAGTGCCATACATACATTTCATTTAATTATCCAATAATCCTACTTACTATTGTTTATTCTCAATTTACAGGTGAGGAAACTGAGACATAGAAAGCTTAAATAATTTGCTCTAGGTCCCTATACTAATTGAGATGTTTTCAGCAGACAAAAATAAGTCACTCTTACGCATGTAAAAATATTCTTTCACTCATAATAAAAGAAATGCAACTTAAAACCATACTGAGATCCTTTTTAAAACTGTCAGATTGGCAAAGATCAAAAAGCTTGTTAAGACTCCTAGCTGGCAAGCATGTGGGAAATAGGTACTCTCATAACAGCTGACAGAAGTACATATTGAAGAGGACAATATGGCAATGTCCTTCAAAATTATAAAAGCACTAACTCTTTGATCCAGTAGTTTCCACTTCTAGGAACTTAACCTTCAGATATATTTTCACCAGATATAAAATGACATACGTAAGAAGTTATTACTGCATCATTTGTAATAGCTAAAGATTAGAAACAATTAATTGCTATGGAACCCTTAAAAAAGGTGGCTCTAAATTCCTTAAGAAAGATATCCAAAACAAATTAAGGGGAAAAGGGAGGGTTGCATAACAGCATGTAACATAACACTATTTGTCTAAAGAATGGGGAAAGAGAAGCGGTTGTCTGTTCACCTCATCCTTGCCACTCCGCCTTATACCTCACCATCGGAGAACTTACCATCCCCCAAATATATCCTGCTGGCACTACACCTTCGTAACTGCTGTTCCCACTGCCCCCACAACACTCCAATCTCCACCTTCCTGCCAACCTTGAGATATTGTATGCATATATACATATTTCCTTTGTTTAAAATACAAATAGCATACTATGCATGCTGTTCTGCACTTTGCTTTTTTTTTATACTTGCAATTAGAGCTGCCTCATTTCATTTTACAGCTGTATACTATTCCATTGAATGGATAAACCATAATTTATTTAATCAGTCCCTCACTGACAGACGTTTCCATTGTTTCCTGTCTTTTGCTATAAATAATGCTGTAATGAATATTCTTGTGCATATTTCACATTAATTTATGGGATTACATCTGCAGGATAAATTCTTAGAACCAATGGTGGTTTGTGGGGAGGGTGACAGGGTGGATAGGTACAGGATTGGGAGACTTTTCACTGTATCTCCTTTTGTATTTTTTTGAATTTTGTACCATATGTATCACCTATTCAAAAAAAATAAAATATTTTTAAATACAGTTGCTGGCCAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119681:ENST00000261978:35
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.169 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0000822=EGF=WD(100=58.8),PF0764510=EGF_CA=PU(0.1=0.0)
A:
NA
C2:
PF0764510=EGF_CA=WD(100=89.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGGCTACACCTGTGACTGTT
R:
GAGATGAAAGCAGGCAAGGCT
Band lengths:
346-757
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development