HsaINT0101828 @ hg19
Intron Retention
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF-like-domains 6 [Source:HGNC Symbol;Acc:3232]
Coordinates
chr1:3415702-3416280:-
Coord C1 exon
chr1:3416152-3416280
Coord A exon
chr1:3415831-3416151
Coord C2 exon
chr1:3415702-3415830
Length
321 bp
Sequences
Splice sites
5' ss Seq
AGAGTGCGT
5' ss Score
3.85
3' ss Seq
CCAGCCCTCTCCACCTGCAGCCT
3' ss Score
8.68
Exon sequences
Seq C1 exon
CCTGCCCGGCCGGCTTCTTTGGATTGGACTGTCGCAGTGCCTGCAACTGCACCGCCGGAGCTGCCTGTGATGCCGTGAATGGCTCCTGCCTCTGCCCCGCTGGCCGCCGGGGCCCCCGCTGTGCCGAGA
Seq A exon
GTGCGTGAGGTCCCTGCTCAGCCCGGGGTGCTGCAGGAGGGGGTGCCAGGTCCTCCGTAGGAGACTCCCTCCTGCCACCTGTCCTGAGTGTCTGAAGCTACCAGGCAACCCCCCTGAGAGTGATGCTTTGCTCACTCGGGCCAGAGCGTTGGTCCTTTTTTGTGGCCACTCTGCTGAGTGGGTGGCCTGAGCCAGAGGGAGGGGAGAGTTGGCCATAGCAGCCGAGGGGACCCCGGCAGATCTGCCCAGCTGGCTGTGATCTGCTGCCAACCCCTGGGGTCCTGCCCACCCCTGGCTCTGACCAGCCCTCTCCACCTGCAG
Seq C2 exon
CCTGCCCAGCCCACACCTACGGGCACAATTGCAGCCAGGCCTGTGCCTGCTTTAACGGGGCCTCCTGTGACCCTGTCCACGGGCAGTGCCACTGTGCCCCTGGCTGGATGGGGCCCTCCTGCCTGCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591-MEGF6:NM_001409:23
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF126612=hEGF=WD(100=29.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCGGCTTCTTTGGATTGGACT
R:
CAGGAGGGCCCCATCCAG
Band lengths:
241-562
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)