HsaINT0101828 @ hg38
Intron Retention
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr1:3498371-3499716:-
Coord C1 exon
chr1:3499588-3499716
Coord A exon
chr1:3498500-3499587
Coord C2 exon
chr1:3498371-3498499
Length
1088 bp
Sequences
Splice sites
5' ss Seq
AGAGTGCGT
5' ss Score
3.85
3' ss Seq
GCCTGCCTCTGCTCCTGTAGAGT
3' ss Score
8.51
Exon sequences
Seq C1 exon
CCTGCCCGGCCGGCTTCTTTGGATTGGACTGTCGCAGTGCCTGCAACTGCACCGCCGGAGCTGCCTGTGATGCCGTGAATGGCTCCTGCCTCTGCCCCGCTGGCCGCCGGGGCCCCCGCTGTGCCGAGA
Seq A exon
GTGCGTGAGGTCCCTGCTCAGCCCGGGGTGCTGCAGGAGGGGGTGCCAGGTCCTCCGTAGGAGACTCCCTCCTGCCACCTGTCCTGAGTGTCTGAAGCTACCAGGCAACCCCCCTGAGAGTGATGCTTTGCTCACTCGGGCCAGAGCGTTGGTCCTTTTTTGTGGCCACTCTGCTGAGTGGGTGGCCTGAGCCAGAGGGAGGGGAGAGTTGGCCATAGCAGCCGAGGGGACCCCGGCAGATCTGCCCAGCTGGCTGTGATCTGCTGCCAACCCCTGGGGTCCTGCCCACCCCTGGCTCTGACCAGCCCTCTCCACCTGCAGCCTGCCCAGCCCACACCTACGGGCACAATTGCAGCCAGGCCTGTGCCTGCTTTAACGGGGCCTCCTGTGACCCTGTCCACGGGCAGTGCCACTGTGCCCCTGGCTGGATGGGGCCCTCCTGCCTGCAGGGTAAGCCACATCTAGGAGTCCAGGGACCGGGGTCCAGGCCTGAGCGAGGGTGCTGGCCTCTTGCAGGGCCCACAGGACACTTGGTGCCTGGGGGAGGGAGGAAGGGGCTGTTAGGACTGAGGACCGTGCCTTTCACCTGTGCCCCTCTCCAGGCAGGGATGGGGAGTGAGGCTGGGCTGGCAGGTCATCCTAGGGGCAGCCCCCTGCAAGGTGCCTGACCCCAAAGTCCAACATGGGGCTGGAAAGCCAGACAGACCCTGTGGGGCCAGCTGGCTGGGGGATGCAGGTTGCTCCCTCTTCCCTGGCCCCAGCCTGCCCTGCCGGCCTGTACGGCGACAACTGTCGGCATTCCTGCCTCTGCCAGAACGGAGGGACCTGTGACCCTGTCTCAGGCCACTGTGCGTGCCCAGAGGGCTGGGCCGGCCTGGCCTGTGAGAAGGGTGAGCGCTGGGCGGCAGAGGAGGGACATACCCCAGCATGCTTGGTGCAGCCCCGCCTGCAGGCCTAGGAGGGCTCCCAGGTCAGGGGGCAGCGCCCTGGGGTGTAGGCTTCAGCTCTGCGTGCAGGAAGCATGGGTCAGGGTCTCCTGGGCCCAGGAGGCAGGACCCTCACCCTCGTGCCTGCCTCTGCTCCTGTAG
Seq C2 exon
AGTGCCTCCCCCGGGACGTCAGAGCTGGCTGCCGGCACAGCGGCGGTTGCCTCAACGGGGGCCTGTGTGACCCGCACACGGGCCGCTGCCTCTGCCCAGCCGGCTGGACTGGGGACAAGTGTCAGAGCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591:ENST00000294599:20
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF079748=EGF_2=WD(100=70.5)
Main Inclusion Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCGGCTTCTTTGGATTGGACT
R:
TCTGACACTTGTCCCCAGTCC
Band lengths:
246-1334
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development