HsaINT0103673 @ hg19
Intron Retention
Gene
ENSG00000078403 | MLLT10
Description
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 [Source:HGNC Symbol;Acc:16063]
Coordinates
chr10:22016785-22019983:+
Coord C1 exon
chr10:22016785-22016857
Coord A exon
chr10:22016858-22019828
Coord C2 exon
chr10:22019829-22019983
Length
2971 bp
Sequences
Splice sites
5' ss Seq
ACGGTAAGC
5' ss Score
9.89
3' ss Seq
TTGAGAATTGTTTTCAACAGATC
3' ss Score
6.74
Exon sequences
Seq C1 exon
ATCAAGATCTTGGAGACAATAGCCGCAACCTAGTTGGCAGAGGAAGCTCACCCCGAGGAAGTCTCTCGCCACG
Seq A exon
GTAAGCGCTATTTACACTGCAAAGTATAGGCAAAGGAAACGTTTGAGATTTGGAAACTTTCTTATCTCATATCAGTAGAGTGTACATTTGTGAGGCTATAAAAGCATTCTACAGATAAGAAGCATGTCTAGACAAGAAAAATGATTCTAAATTAATTTAAATATTAATTTAAACACCATTAGATTTCTAAGTAAAACAAATCCCTTTCCTTTGGTTTCCAATCAGTTCGAACTCTCTTGTATTTATTACCTGTATACTGATTTGAGTAATTCTTTTTGATCATAAAATAGTTTTAAGATCTCTTAAAGTTGTAGACCCAAGACTTTCAAGTTTGGGTTCCAGTTTTAGCTCTGTTCTGTGTAGCACTTAATCCCTTAGTCTCTAGTTCCTAATTCAGTAAAGTCGTGTGGTAGATCACTAAACTCCTACTAGTTCTTAAATTGTTTGAATCAGTTATAGCAAATGTATTACAAGTTTTTTGAAATCATTTTATGACAGTATTCAGGTACCATTTATTAAAATCTAATTAATATATTTGGGGTTATCAAACTGCATATTCCTTCTGTTCTAAATGGGGAGAATGTGGTATGAGATACTGTGTCTGCTTGTAGGGGAGAATGGAACTTTGGTGATAGCTATCTCCTTATTAATTTTATTTCCCTTCTGTGCGTTCTCTTTGTTTTCTCCATGTTCTCTAATTTAGGAACCCTCCCTCAAGCATGGTGTTAGACTGGGTGACAATGGAGAGTAAGAGAAAAGCCCATTCTAGGGTCTTTCTTCCAAGAATGGGAGAAACGTGATTAAAAATGAAAACTTTGGTCAGGCGTGGTGGCTCATGTCTATAATCCCAGCGCTTTGGGAGGCCAAGTTTGGAGGATTGCTTGAGGCCTGGAGTTCAAGACCAGCCTGGGCAACATGCCAAGACTCCATGTCTACAATTTTTTTTTTTTTTTTTTCCAAAATGAACTTTTTCATGTGATGACAGATCATGAATAACAGTATTGCTGATATATTTGGGGAATGTCTGTTAAGGAACATCTTCTTTATCCTAAAGATTAGTTCAGTAACCACTAATTTCATTTTCTAATGGTACATCTAGTGATGCCTTTTTTTCTGTATAATTCCTGGGTGAACTAAAAGTAGTATTGTTTTCCCTGATTGAACTCTGCAGAAAATCAAATATCCATTCTTTGGAAACCAGGAATCTGAAGAACAATGATAACATGATCTGACTAGTCTGTGATTTTATGCTGTGATTAATTCTATGTTGTTTTTCTTTTCAAAGAAGAAAGTTAATGTTTGCTCAGTGTTTAGTGGAAGAAGCATTTCTCTGTTGCCCTTTTAAACTTAAAATATTACAAGCTACCGAGAATTATTAAGAAAGTGCTATTTTGCTTAATATAGTTTTTCCTTTTCATTAGTTAAATGGGACTTAACAAATGGTACTAAATTATTTTTAGCATATTATTTCCAACTTTATATTACTCTTTAGAAATCAGCCTGAGATGTAACAGCCTAAATTATCCTGGTATAGTGTACTATTTGCAGAGGGATGGCCAACTGTATGTGGCCCATAATGTTTACATATGGAATAAAAACCCCATTTGTTTAACATCTTACGAAAATTTTGCAGAGACGCATATTAAGGCAGTGTCAAGAACACTAGTGGGTTGTTAGAAGACCTGAGTTGTATAGCCCAGCTCTTGTCACCTCACCAGCAGTGTGTCTTTGGACAAGTCACTAAAACTCCGTCCTGTTTCCTCATTTGAAAATGGAGCCAATAAACCAGGTTTTGACTTCTCACTAGGTTGTTGTGGAGATCATATGAGATATATACAAACGCATTGGAAATTCTAAAGCTCTTTAAATGTATTATGTTAGAATGATAGCTGGAGACCGGAAATGGCCACACTTATTTAAACCAAAAAGTGTAGAGAACATTACATGTTCATCTTAATACAAGTGCTGTTTGTTTTAGAAGGGTTATCATTTGAAGTATAGATCTAAGACATTTTAGAAATATTCATGTAAAAGGATCAAAAATTGCTTTGGGGGCTGGGCACGGTGGCTCATGCCTATAATCCCAGCAGTTAGATAGAGAGGCCTGGGCGGGAGGAACACTTCAGCCCAGGAGTTGGAGACTAAGCTGGGCAACATGGTGAAACTCCGTCTCCCCTGCCCAACCTCCCCCACCGCCGCCTCCCCGCCCAAAAAAAAGCTGTGCGTGGTAGTGTGTGCTCTTGTGGTCCCAGCTGCTCAGGAGGCTTGAGGTGGGAGGATTGCTTGAACCCAGGACCCAGGAAGTCAAGACTGTAGTGAGCCATCATTGCACCACAGCACTCTAGCATGGCTGACGAAGTGAGACCCTATCTCCAAAAATGAAAAAAAAAAAAAAAAAAAATTGCTTTGATCTTATTTCTTAATTGTGAAAATACTTGAAAATGAGTAATTTTTAATTTATAACAAAAGGCTGCTTTAAGATTCTTAAAAATTTCTTTTTAGTGACATTTGAGATTTTAGTTGGTTGTAAATTCAAATACCTTTTACAGTATTATACTTTTTCAGGTTATTATGATGGCAAATATATCAAAGCAGAATGGTGAAACCCTTTTCTGGGAAATTATTTTTAAGTCTAATTTTGTCTTTCCCTCTTTTGTCTTATAATGCCATACCAAGTTATTTTACAGCCTATTTCAGAGATTGTTGGTGGTGTGTTTATATTTTCTAGTGGTTTTTAATTATCTATGATGGCTAGCTATTTCCTTGATTCTATAATATTGGGAGGAAGAATGATAATTACTCAATTTTAGGGTAGATTATGGTTTTCTAAATCCAGGAACCTGATACTTCTGGCATAGGCAGCCTGGTGTTATAAAACTCATACAGGAGAAAAGGGGTCAGCTTAAGGTAAGAAACTGTACTCTCTTAAAAGCATTCCCCTTCTTTTTAACTTGAGAATTGTTTTCAACAG
Seq C2 exon
ATCCCCTGTAAGCAGCTTACAGATTCGCTATGATCAACCAGGCAACAGCAGTTTGGAAAATCTGCCTCCAGTAGCAGCCAGCATAGAACAGCTTTTGGAGAGGCAGTGGAGTGAAGGACAGCAATTTTTACTAGAACAGGGTACTCCTAGTGACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078403-MLLT10:NM_004641:17
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=NA C2=0.703
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)