HsaINT0106842 @ hg19
Intron Retention
Gene
ENSG00000117983 | MUC5B
Description
mucin 5B, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:7516]
Coordinates
chr11:1281581-1281958:+
Coord C1 exon
chr11:1281581-1281623
Coord A exon
chr11:1281624-1281855
Coord C2 exon
chr11:1281856-1281958
Length
232 bp
Sequences
Splice sites
5' ss Seq
AGGGTAAGT
5' ss Score
10.45
3' ss Seq
TCTGCCTTTCCTCCTCCCAGACT
3' ss Score
10.04
Exon sequences
Seq C1 exon
GGGAGCCTCAGGAAAACCGGCTGCTGCTACTCCTGTGAGGAGG
Seq A exon
GTAAGTGGAAGCCACCTTCCCACACCAGCCCTCCAGCTCCAGCCCGTCGCCACCCATCCATTCCTGCCCAGACATCTGCACTAGGCAGCAGTGGGATGCCCGCGTCCAGACTCCACCCTCGGTCCTGGAGGGCCATGGGAGGGGTGGTCCCATGGGGAGGGTCGGCCCAGCAAGTCCAGGCCCTCAGAGTGAGGGTCCAGTGGGGCTCCACATCTGCCTTTCCTCCTCCCAG
Seq C2 exon
ACTCCTGTCAAGTCCGCATCAACACGACCATCCTGTGGCACCAGGGCTGCGAGACCGAGGTCAACATCACCTTCTGCGAGGGCTCCTGCCCCGGAGCGTCCAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000117983-MUC5B:NM_002458:47
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGAGCCTCAGGAAAACCG
R:
GCAGGAGCCCTCGCAGAA
Band lengths:
132-364
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)