HsaINT0106873 @ hg38
Intron Retention
Gene
ENSG00000184956 | MUC6
Description
mucin 6, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:HGNC:7517]
Coordinates
chr11:1013899-1018770:-
Coord C1 exon
chr11:1015762-1018770
Coord A exon
chr11:1014002-1015761
Coord C2 exon
chr11:1013899-1014001
Length
1760 bp
Sequences
Splice sites
5' ss Seq
CCGGTAAGT
5' ss Score
10.91
3' ss Seq
ACCGTCCACTCGGCTACCAGGGG
3' ss Score
6.8
Exon sequences
Seq C1 exon
CAAAATCGACCAATCAGGAACTGCCAGGAACAACGGCCACCCAGACGACAGGCCCACGTCCAACCCCAGCAAGCACCACAGGCCCAACCACCCCACAGCCAGGACAACCCACGAGGCCCACAGCCACAGAGACCACTCAAACAAGAACGACTACTGAATACACAACGCCCCAAACCCCACACACCACACACTCCCCGCCTACGGCGGGGAGTCCCGTCCCTTCCACAGGTCCTGTCACTGCAACATCTTTCCATGCCACCACTACCTATCCAACCCCATCACACCCTGAGACCACACTTCCCACTCACGTTCCACCTTTCTCCACCTCCTTGGTGACTCCAAGTACTCACACAGTCATCACCCCTACCCACGCACAGATGGCCACATCTGCCTCCAACCACTCAGCGCCAACAGGTACCATTCCTCCACCAACAACGCTCAAGGCCACAGGGTCCACCCACACAGCCCCACCAATAACGCCGACCACCAGTGGGACCAGCCAAGCCCACAGCTCATTCAGCACAAACAAAACACCTACCTCGCTACATTCACACACTTCCTCCACACACCATCCTGAAGTCACCCCAACTTCTACTACCACGATTACTCCCAACCCCACTAGTACACGCACCAGAACCCCTGTGGCCCACACCAACTCAGCCACCAGCAGCAGGCCACCACCACCCTTCACCACACACTCCCCACCTACAGGGAGCAGTCCCTTCTCTTCCACAGGTCCCATGACGGCAACATCCTTCAAGACCACCACTACCTATCCAACCCCATCACACCCTCAGACCACACTTCCCACTCACGTTCCACCTTTCTCCACCTCTTTGGTGACTCCAAGTACTCACACAGTCATCACCCCTACCCATGCACAGATGGCCACTTCTGCCTCCATCCACTCAATGCCAACAGGCACGATTCCTCCACCGACAACGCTCAAGGCCACAGGGTCCACCCACACAGCGCCAACAATGACGCTGACCACCAGCGGGACCAGCCAAGCCCTGAGCTCATTAAACACAGCCAAAACCTCTACATCCCTACATTCACACACTTCCTCCACACACCATGCTGAAGCCACCTCAACTTCTACCACCAACATCACCCCCAACCCCACCAGTACAGGAACCCCACCAATGACAGTGACCACCAGTGGGACCAGCCAATCCCGAAGCTCATTTAGCACGGCCAAAACCTCTACATCCCTACATTCACACACTTCCTCCACACACCATCCTGAAGTCACCTCAACTTCTACCACCAGCATCACCCCCAACCACACCAGTACAGGCACCAGAACCCCTGTGGCCCACACCACGTCGGCCACCAGCAGCAGGCTACCCACACCCTTCACCACACACTCCCCACCTACAGGGACCACTCCCATCTCTTCCACAGGTCCTGTCACTGCAACATCCTTCCAGACCACCACTACCTATCCAACCCCATCACACCCTCACACCACACTTCCCACTCACGTTCCATCTTTCTCCACCTCCTTGGTGACTCCAAGTACTCACACGGTCATCATCCCTACCCACACACAGATGGCCACTTCTGCCTCCATCCACTCAATGCCAACAGGCACCATTCCTCCACCGACCACGATCAAGGCCACAGGGTCCACCCACACAGCCCCACCAATGACACCGACCACCAGTGGGACCAGCCAATCCCCAAGCTCATTTAGCACGGCCAAAACTTCTACATCCCTACCTTACCACACTTCCTCAACACACCATCCTGAAGTCACCCCAACTTCTACCACCAACATCACCCCCAAACACACCAGTACAGGCACCAGAACCCCTGTGGCCCACACCACCTCGGCCAGCAGCAGCAGGCTACCCACACCCTTCACCACACACTCCCCACCTACAGGGAGCAGTCCCTTCTCTTCCACAGGTCCTATGACTGCAACATCCTTCCAGACCACCACTACCTATCCAACCCCATCACACCCTCAGACCACACTTCCCACTCACGTTCCACCTTTCTCCACCTCCTTGGTGACTCCAAGTACTCACACAGTCATCATCACTACCCACACACAGATGGCCACTTCTGCCTCCATCCACTCAACGCCAACAGGCACCGTTCCTCCACCAACAACGCTCAAGGCCACAGGGTCCACCCACACAGCCCCACCAATGACAGTGACCACCAGTGGGACCAGCCAAACCCACAGCTCATTCAGCACAGCTACAGCCTCTTCTTCCTTCATATCCTCCTCGTCTTGGCTGCCTCAGAACTCTAGCTCAAGGCCACCGTCATCACCTATCACCACACAACTCCCCCACTTGAGTTCTGCAACCACTCCTGTTTCCACAACTAATCAGCTGTCCTCCTCATTTTCTCCCAGTCCTTCTGCCCCCTCTACTGTTTCTTCTTATGTGCCCTCCTCCCACTCCTCTCCCCAGACTTCATCGCCTTCTGTTGGCACATCTTCCTCTTTCGTGTCCGCCCCCGTGCACTCCACAACCCTGAGCTCGGGGTCACACTCCTCATTGTCCACTCATCCCACGACTGCATCAGTGTCTGCATCTCCTCTTTTTCCTTCTTCTCCAGCTGCCTCTACTACCATTAGGGCCACTCTCCCCCACACTATCTCCTCTCCTTTCACCCTCTCTGCTCTACTCCCCATATCCACTGTTACCGTGTCTCCCACCCCATCCAGCCACCTAGCCTCCAGCACCATTGCATTTCCGTCCACGCCCAGGACCACGGCCAGCACCCACACCGCCCCTGCCTTCTCCTCTCAGTCCACCACCTCGCGGTCCACTTCTCTCACCACCCGAGTTCCCACATCAGGCTTTGTGTCACTCACCTCGGGGGTGACGGGTATCCCCACCTCTCCAGTCACCAACCTTACCACCAGGCACCCTGGTCCCACCTTGTCGCCTACCACACGGTTCCTGACCAGCTCCCTCACTGCCCATGGAAGCACCCCTGCTTCTGCCCCGGTATCTTCTCTCGGGACACCTACGCCCACCTCACCCG
Seq A exon
GTAAGTGGCATCTCTGTGGCCCTTCTCCTGGCCTCACCTCTGTGCTCATGACTCCCAGGCAGCCCCTGCCTCAGCTTACCCCTCATGGTCCTGTGATCCCAGGACCACACGCCTGTTCCCTGCCTTCCCTACACACCTGCCAGGCGTTTCCACTCTCCTCTCCTGGGCACCCTCTATGCCAACGCTGTCCTGGCCAAGCAAGTGCCTGGCCTCCCCGTTGGGCCTTGTTCCCCAGCTAACCTTGACCTTTCCCTGCACTGGCTCACTCATGCCCGGTCACTGCTGCACTCCTGGCCTCCCCTCAGAGTGTTACCTGCCAAAAGCCTTCCCTGGCTGCCCCTTTGGTTGCTCAGAGGATGTCAGGGCTGGCCCAACCCCAGGGTTCAAGCAGCACAGCCCTTCCTCCAAGTGCAGAGAGAGACACAAAAGTCTGGCACATCCCCTGCCTCGCCCCAAAGGACCTGTTGAAGGTGGAGCTGGACCTGGCAACCAGGGCACCTGCTCCTTCGTGCTCATGCCAATTCTCTGGGCCACGGTCTCTTCCCGGCCCATGCCTGTGAGCGAGTCCACTGCTCCCCAGGCCATGGGATGCCTGGGGACAGAGCACACCTCAGGCCTTATCCATGTCCACCTCACCTCACCTCGCGTTCCAGGGATGTCCCTCCCTTCCCTCCTGGGTGTTCCTCTCACAGCAACCACCCAGGGACTGGGTCCCTCGCATGCATCGACCTCCACCAGGCGACAACGCCACAGTTGCCTTCGTGGTCTCTCACGTGGGTGGCAGCTCGTTGCTGCAAGCTGAGGGAATCTTGGTTCGGGTCCCTCCCTGAGACCGGGACTTGGGTGCAAGGTGTAACCAGGGAGGTGACCCCAAGAAGCAGAGGCGAGGGAGCAGGAACCAGCTGGGAGGGGAGGGCAGCTGGGGACGGCAGGGCCTATGGAAGCACCCAGAGTCCTGACCCTCCCGGAGAAAGCCCTCTGCAGCGGGCAGGTAGGCTCCAGGTGACCTGTCTTCTCTGCAGCCAGGAAACGAAGCTGGGAGCAGCCAGGGGAGGGCACACGGGCAGCAGAGTCCAGCCTTTACCCCAGGACTCCTTTTCCACTTTTAAACCCACGCTCTCCAGTGGCGGTTTCTAATGCCAACGCTGCCACTGCCTGCATCGGTCCACCCTGCTCTGTGCTGCCTGCCACGTACCCAGGCCTCTCGCTGAGGCTGGCTGTCTCTGGGCCTTCCCCGCGGGCCCCCACCCCGCCCCTTCCAGGAGCCCAGACCACGGGGCCTGCTCCACTTCCCTCCTCCCCAGCTGGGGCACACGGAGCTCCTGCAACACCATATGTCCCGCTCTGGGGTCACTGGCACGGTGTCCTCGGCCCCCCTGCAGGTCCTGGGTCTGGCCAACCAGAGAGGCCCATGCCCACAGGTCAGTGTTGAGGCCTGGGGTTGGTCATCAGGGAAGCTGGGGCCCAAGGGTGGCTCACACAGGCCCAGGGCTCAGTATCTGCTGAGTCCGCTGAGAAAATTCTCTACCTTATGGACTCCAGCAGAGCGACTTTGAGGGGAAAAAACAAACTAGGATGCGGCTGGCCTTTGCCTTTGTGTATGGCTGAGGTCTGAGCTCTGTGGGGCTCCACAAGGGGAGACCACACCTTGGGCAGGAGAGTCCAGAGACAGGTGGGGACCCCGGTCTCTAGCCAGGGTTTCCCTCCCTCCTCGCTCCATGCCCACCCTGGGCGCTGCTGACCGTCCACTCGGCTACCAG
Seq C2 exon
GGGTCTGCAGTGTGCGGGAGCAGCAGGAGGAGATCACGTTCAAGGGGTGCATGGCGAACGTGACGGTAACCCGCTGTGAGGGCGCCTGCATTTCCGCTGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000184956:ENST00000421673:31
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.945 A=NA C2=0.200
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACCATTGCATTTCCGTCCAC
R:
TGAACGTGATCTCCTCCTGCT
Band lengths:
350-2110
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development