HsaINT0107504 @ hg19
Intron Retention
Gene
ENSG00000133392 | MYH11
Description
myosin, heavy chain 11, smooth muscle [Source:HGNC Symbol;Acc:7569]
Coordinates
chr16:15847251-15850371:-
Coord C1 exon
chr16:15850198-15850371
Coord A exon
chr16:15847366-15850197
Coord C2 exon
chr16:15847251-15847365
Length
2832 bp
Sequences
Splice sites
5' ss Seq
AAGGTACCA
5' ss Score
7.87
3' ss Seq
CAGCAGGGTGTCCTTGGCAGGTG
3' ss Score
4.21
Exon sequences
Seq C1 exon
AACAACCCTCCAGGTGTGCTGGCCCTGCTGGACGAGGAATGCTGGTTCCCCAAAGCCACGGACAAGTCTTTCGTGGAGAAGCTGTGCACGGAGCAGGGCAGCCACCCCAAGTTCCAGAAGCCCAAGCAGCTCAAGGACAAGACTGAGTTCTCCATCATCCATTATGCTGGGAAG
Seq A exon
GTACCAGCCACAGGGCCCAGGGGACTCTGTCTCAGGGGACCCCCAGTGGCTGCTCAGCGCAGAGACAGTCTGAGAGTGGCAGAACCTTGGGCTGCCTGGAAACTGCAAAGCCATCTGCTGCTAAGCGAATCCCAACCAAGTCCTATTCGTAATTTGTCTACGCATCTGTAAGGCATCAGCTGTAGCCACTCTCATGTTTTCCAACCGTGACGTCCAGACAGTTATTTCTTTCTGTTTTTGTTGGAGACAGGGTCTCGCTTTGTCGCCCAGGCTGGAGTGCAGTGGTGCGATCATAGCTCACTACAGCCTCAACCTCCTGGGCTCACACGATCCTCCTGCCTCAGCTTCCCAAGTAGCTGGGACTACAGGTGTACACCACCATGCCCAGCTAAAATCTTTTTTCCTTTTTGAGATGGAATTTTGCTCTTGTCATCCAGGCTGGAGTGCAATGGCGTGATCTCTGCTAACTGCAACCTCTCCCTCCGGGTTCAAGAGATTCTCCTGCCTCAGCCTCCCAAATAGCTGGGATTACAGGCACCTGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGAAGGGTTTCGCCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCACCCGCCTCGGCCTCCCAAGGTGCTAGGATTACAGGCATGAGCCACCGTGCCTGGCCGCCCAGCTAAATTTTTAAATTATGTATAGATATGGGGTCTTGCTGTGTTGCCCAGGCTGGTCTTGAATTCCTGGGCTCAAGAGATCTCCCTGCCTCGGCTTCCTGAAGTGCTGGGATTATGAGCACGAGCCACTGTACCTGGCCTCAGCCTGCTTTTCTTGTATAGACTCTAAATCCTTCCTGCTACAAGTTATACCCAACAGGCGGGGCCAACTGGAATGGGGTGACTAATACATCCACACCTGGCTTCAACAAAAATCTCCCATGTCACGGTCTTGAGTTTGCTATTGCCAGCCTGCTCTGGCCAGGGAAATCTATGATAGTTGTATTCATCATCATCATCATCATCATCAACATGCCTTGGCTGTTATTGTATAGGCCCTTGCCCTGTGGCTCTCAAGAGTCCTGGATAATGTACAAAGGACATAGCTTAGTCTGGCTTGCAGAATTGTAGTATTCTATTGACTCCTCAGTACCTCCACTGCATCATGGGCACAAACAATGCTCTCTACCAGGGCCTGGCAACAGAGTCCGATCTGGCCCACAGCTTGTTATTGTAAATAAAGTTTTATTGGAACACAGCCATGCCCATTTGTATGCATAATGTCTATGGCTGGCTGCTTTTGTATACTACAGTGCTAGAGTTGAGTAGCTGCGACAAAGACTGTATGACTTGGCTGGGTGTGGTGGCTCACGCCTGTAACCCCAGCACCAAGGCAGGTGGATTACTTGAGGTCAGCAGTTTGAGACCAGCCTGGCCAACATGGCGAAAGCCCGTCTCTGCTAAAAATAAAAAATAAAAAAAATTTAAAAATTAGCCAGCTGTGAGATTACAGGCACACAACTGTAACCTCAGCTACTCAGGAGGCTGAGGCAAGAGAACTGCTTGACCCAGGAAGTTGGAGGTTGCAGTGAGCTGAGACTGCACCACTGCACTCCAGACTGGGCAACAGAGAACCACTCTGTCTCAAAAACCAAAACAAACAAACAAACAAAACATTGTATGACTTGCCAAGCCAAAAATATCTACTATCTGGGCCTTCACCAAAAGTTTCCCAACTCCTAGCCTATATTCAAGGGGGTATATGTTCCTTTAAGCATATAGAGACAACACTTTTCTTTTCCCTACTTCATCAGTGGATTTTTTTTATTATTATTTTCAGTCTTCTCTCAGATCAAGCCTACCTATTATCCTGATAACCCACATCCCATGATAACCCAGCAAAGCTGTATTATCAGTTCCTTTCATTTAATATTCACCATAGTAAAAATTACGGCTTTGGGCATTGTCATTGTTTGAGTCAGGAATGTAAAAAGCCTATATGTCCTTTTTCTGTATATCCATATATCAGGATCTCTGAGTTACAAATTATGCTCATTAGAGAGTGGAAAATAGGATGCCATGCTTAATTAATTTATTTATTTAATTATTTTGAGACAGAGTCTCACTCTGTCACCCAGGCTGGAGTTCAGTGGCGCAATCTCAGCTCACTGCAATCTCCGCCTCCCAGGCTGAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGCATTACAGGTGTGCACCACCATGCCTGGCTAATTTTTTTTTTTTTTTTGTATTTTTAGTAGACATGGGGTTTCACCATGTTGGTCAGGTTGGTCTTGAACGCCTGACCTCAAATGATCCACCCACCTTGGCCTTCCACAGTGCTGGGATTACCAGTGTGAACCACCACGCTTGGCTGCCATGCTTAATTTCTAAACCAGGATGATTGGGAAGATGATGAGGGGGGAGTTTTGCATGTCGGCAGGAGGGCATCTGCCGTCATGAAATCTCTTAATAGTGTATAACTCACAGGTACTGTGCTGGCTTAGGAGGAGGGAGGCTACCACAGCAGCGTTAGTAGGAGAATATGGAATGGAAACTAGGCTTTCCCAGCAATGGCTATCACTGGCTGATGTCCTACTACGTGGGCACAGGTCCCTGGGCTGTTGGTCTCTTCACTGGTGTTTGTGGAGTCCCATCATGGTGGTCATAAACGTCATTTCCTCTCTGACCTCAGAAGATCTGGAAGGACAATGGGAGGGCTGGGGTCCTGGCCTTGGTTTCTAAGTTTCTAGTTTCCCAGGGGTTCTGACCAGCAGGGTGTCCTTGGCAG
Seq C2 exon
GTGGACTATAATGCGAGTGCCTGGCTGACCAAGAATATGGACCCGCTGAATGACAACGTGACTTCCCTGCTCAATGCCTCCTCCGACAAGTTTGTGGCCGACCTGTGGAAGGACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133392-MYH11:NM_001040113:15
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.052 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(8.3=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(5.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)