HsaINT0107851 @ hg19
Intron Retention
Gene
ENSG00000092054 | MYH7
Description
myosin, heavy chain 7, cardiac muscle, beta [Source:HGNC Symbol;Acc:7577]
Coordinates
chr14:23892756-23893358:-
Coord C1 exon
chr14:23893116-23893358
Coord A exon
chr14:23892933-23893115
Coord C2 exon
chr14:23892756-23892932
Length
183 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGG
5' ss Score
10.51
3' ss Seq
ATGGGATTCTTGGTCGGCAGGTG
3' ss Score
4.66
Exon sequences
Seq C1 exon
GAACAAGACAACCTGGCAGATGCTGAGGAGCGCTGTGATCAGCTGATCAAAAACAAGATTCAGCTGGAGGCCAAGGTGAAGGAGATGAACGAGAGGCTGGAGGATGAGGAGGAGATGAATGCTGAGCTCACTGCCAAGAAGCGCAAGCTGGAAGATGAGTGCTCAGAGCTCAAAAGGGACATCGATGATCTGGAGCTGACACTGGCCAAAGTGGAGAAGGAGAAACACGCAACAGAGAACAAG
Seq A exon
GTAAGGGCAGCTCCCTTTGGCTCCAGCCCGGGTCTCATCAGGACTCTCAGACCATACTGACCTTGACCCAGGCTAGCCACTCGGCATCCAGAGAGCAGCATGGACCTTGACATGGAGCTCCCCACAGATGGCACCAAGCTGGTGACCTTTGACCCTAAAGGAGATGGGATTCTTGGTCGGCAG
Seq C2 exon
GTGAAAAACCTGACAGAGGAGATGGCTGGGCTGGATGAGATCATTGCCAAGCTGACCAAGGAGAAGAAAGCTCTGCAAGAGGCCCACCAACAGGCTCTGGATGACCTTCAGGCCGAGGAGGACAAGGTCAACACCCTGACTAAGGCCAAAGTCAAGCTGGAGCAGCAAGTGGATGAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000092054-MYH7:NM_000257:23
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.481 A=NA C2=0.508
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(41.9=100),PF0157614=Myosin_tail_1=PU(26.4=42.0)
A:
NA
C2:
PF0157614=Myosin_tail_1=PD(28.8=93.2),PF0157614=Myosin_tail_1=FE(45.0=100),PF0003816=Filament=PU(6.4=30.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAAGCTGGAAGATGAGTGCT
R:
TGGCCTTAGTCAGGGTGTTGA
Band lengths:
249-432
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)