HsaINT0108921 @ hg19
Intron Retention
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:7606]
Coordinates
chr11:76919742-76922382:+
Coord C1 exon
chr11:76919742-76919848
Coord A exon
chr11:76919849-76922196
Coord C2 exon
chr11:76922197-76922382
Length
2348 bp
Sequences
Splice sites
5' ss Seq
CAGGTGGGC
5' ss Score
8.07
3' ss Seq
ACCTGCTCTGTCTCTGACAGGAG
3' ss Score
10.37
Exon sequences
Seq C1 exon
GAATTGTGCCCTCACTCACCTACCAGGTGTTCTTCATGAAGAAGCTGTGGACCACCACGGTGCCAGGGAAGGATCCCATGGCCGATTCCATCTTCCACTATTACCAG
Seq A exon
GTGGGCACCTCTGCACTCTAGTTGCCTTCGTGCACAGCTAGCGTTGCTGTACTTTGGCCCTGAAAGCAGAGACCCACTGACCTTGCCAGGTGTGGGGCCCGTACCAGCCTGGCCTCAAAGGGATTCCTGCCAAGACCACTGGAGCCCCAAGGGATGGCCCAACCCCTGATCCTTGTATCTTCTGATTCTTCAGCCCTTAGGGGCTTGACAGTTCCTCCTCTGAGCTTCCGATCCCTACCTGTTCAGGCCCCTCCTTCAGTGCGGGGCTATCCTCTGACTTCGAGATTCTGCTGTTGTAACTGGGTAATTCCAAGGCCTCTGTGCAAACATTTTCTAGCATAGGCACCTGCAGGAAGCCGGGAGGGAAGCTTGCATGTTGAGCCTCTATTATGTGTCTGGCACTCTTCTCTCATTCTGTCCTCCCAACTAACCCCAAGAAGCAGGCATGTTGTCCCCATTTGACAGAGGGACAAAGAGACTCAGGCCGCGTGCTGTGATTAGGATCACACAGCTGATGGAACTGGGGTTTGATTCCAGGTCTTCATGACTGCAGGTTGGTGCTCTTTTCTGGGCTCAGCCTGCTTACCATTCTGTGGGAGAAAAACCATGATGCTGGGAAGGGCAGAGGAGGCAGGGACGGTGGCTGCTGTGGCAGAGAGGACACTGGCCTGGGAGTGAGAAGGACTGCCCTCATCCAAACCTGGGATCTACCTTTCCTCATGCCCCTCCCCACCCACCCCATGCTGCCCACTGAGTGCATGGCCCCTGGACTACCAGTTCCCCCAGAGTCAGCCTTGACATCTGCTCCTCCTGTCCCACGTCCCAAATCACTTACCTGATGACTGTACCTCCTGGATATCTCTAAAGTCCCCCATGTCTCTCCATCACCACCTTCCCAACCTGGGTCAGTCTACCATCATCTCTGATCCAGAATGGAGGCAGTGACCTTCTCCCTGTTCTCCTCATCCATTTTGGTCCTTTCAATCCTTTCTCCACAGGGTGGTCATCCTGCTTTCCAGATTCCCCCAGTGGATTCCCCTTGCTCGTAGGGCATAACCCCCGTCCTGGCCGTGGCCCTGCCTGGTGGTGCCACTAACTGCTCCTGCTGCCTTGCCTTGTACCTGGCTCTCCTTCAGCTCAGCTGGATTGTTTCCGCTTCTCAAGTGTGCCACAGGGCCTTTGTAATGTTGGGATGCTCTTCCCTCAGTTCCTTCCCTCACCTACTGAGCTTTTAGATGTCAGTCAGCCATTTTATCTTAAAGGAAGTCTGCCCTGTCCTCAAGCCTAGATTAGGTCACCTTGTTATATTCTCTTACAGCACTGTGGACAATTCCTTCAAAGGTTGTCATTATATATCTGTTTGGTATGATTTTTAATGTCTGTCCTTGCCCTGAGACTACAAGTTCCATGGAAGTAGGGAGGGTAGGCATTGTTGCTTAAAGGGCCTGGCTCATAGATGTTCAATGCATGCTTGTTGGATTGACAGATGGGTGAGTAGGTAAACTGGTGGCTCAATGAACATAGAGATGGGAGGATGAATGCTGAGTGAATTGATGGGTGGATATTGGTAAGTGAATTGGTGAGTTAGGTAGGTGAGTGGGTGGATGGGTGGGTAGATGGATGGACAGATAGGGAGATGGATGGAGGTAGATGTGTAGGTAGATAGACCCATAACCACATGGATGGGTGGGTAGGATGGATAATGATTGACTCAGATCTCTGACTGACAATGTATCCTCAGGCCAGCCTCAGTTTCTCTACCTTTCAAATTGTGTATAAGATGACCATAAGGCTCTAGGAGTCTGTGGGCAGCGCCAGCCCTTCAGAGGCTTCATCTCTGCTCTGGGCCCATTCCCCAGCCTAAGTTCCTCTGGTTTTGGGTCTGGAAGTTCAAGGGGGTGGGAGGGCCTCTGCTACTGCTAATGAAAGCAGCTGGTCTCAAGAGAACCCAATGCAAGGAGGCCAGACTGAGAGGCTCTTCCAGAGGAGGATGGGCCCAGGAGGTGAGGGGTATGGAACAGTCTCAGGGTTGCCAGCTGGTCACTCTGAGTTTCTTCATCTTGAAATGGGGCTGCTCATCTCACTGGACTGTTATGGGGGGACATGAGGTAACAGACATGGCCATGCACTCCAACTGCCAACTGCTGAGTCTGTGCAGGCAGACTTGCTCTGTCCCTGTCCTGTGCCGTATCCCCTGGGGGAGCAGTGTCAGCTGAGGCTGGAGAGGTGGGTGGGCCCATGTGCGGGGTAAGGTGGTAGACCCCGGCGTTGGGGGTCTTGGTGTGGTGGGAAAGGAGCCCACTTCTGCCAGGTCCCTGCACGCCTGTGACCTGCTCTGTCTCTGACAG
Seq C2 exon
GAGTTGCCCAAGTATCTCCGAGGCTACCACAAGTGCACGCGGGAGGAGGTGCTGCAGCTGGGGGCGCTGATCTACAGGGTCAAGTTCGAGGAGGACAAGTCCTACTTCCCCAGCATCCCCAAGCTGCTGCGGGAGCTGGTGCCCCAGGACCTTATCCGGCAGGTCTCACCTGATGACTGGAAGCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474-MYO7A:NM_000260:44
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF093795=FERM_N=PD(18.1=47.2),PF0037313=FERM_M=PU(10.8=33.3)
A:
NA
C2:
PF0037313=FERM_M=FE(55.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)