HsaINT0108948 @ hg38
Intron Retention
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:HGNC:7606]
Coordinates
chr11:77158277-77159523:+
Coord C1 exon
chr11:77158277-77158430
Coord A exon
chr11:77158431-77159446
Coord C2 exon
chr11:77159447-77159523
Length
1016 bp
Sequences
Splice sites
5' ss Seq
AGGGTGAGG
5' ss Score
7.13
3' ss Seq
GTGCCCCTTGCTGCCAACAGCAC
3' ss Score
6.57
Exon sequences
Seq C1 exon
GGTAACTGCATAACCTGTGAGGGCCGGGTGGACAGCCAGGAGTACGCCAACATCCGCTCCGCCATGAAGGTGCTCATGTTCACTGACACCGAGAACTGGGAGATCTCGAAGCTCCTGGCTGCCATCCTGCACCTGGGCAACCTGCAGTATGAGG
Seq A exon
GTGAGGCTGCGCCACACTCGCCCTGCCCCACCCCTGCGCCAAGGGCAGTGCAGTGCCTTGCTGCCCACGTGGTATTGGCAGCTCAGTTTCTGTCCTAGCACGTGCCCTCTTTGGGATGGAAGCTGGGAAGAATTCGCCTGTGGGTAGATTTGAACAGGTCTGCTAGATTGAAATCAGCGGTGGGTGTGGTGTCGCTGTGCTGACAGTCCACCACGGAGAGGTACAGTTAAAGTATATTGGGAGTTGTCTATGGACACTTTAAGACTCACTTCAAATTTGGTTTCTTCTTTAAAGTCACATGTCTTAGAGAGAGGGTAAATCTTTGAACTAATTCACTCTAAGGTGTGAGTGACTGGATAGCCATCTTTGGAAAGGGAGAAGGCTAGGGAAGGGAACGTGTTCACTCATCTAACATTCTTGGACACCCACTATGTGCCAGGCTGGGAGGTGATCCCCTGAGGCAGGTGGCAGGTCCCACTCTGCTCTTGCCCCTGATTCCCAGCATGGTCCCCAGGCAGAGTAGGAGCCCCAGGAAATGTGCCCAAGGAATGAATGATCCCAGCACTAAGGAGATCACAGTCTAGGCATCTTGAAAGACTAAGAGACACAGGGAAGGGTAAGCTGACAGCAGGAAGAGCTTGTGCAAAGGTCCTGAGAACAGAGCACATGTCGGGGAGGGGATCCAAAGCTTGTCTAACAGGAGCCAGGGCTGCTGCCAAGAGCCCTGGGAGTGGGGAGAGAGCTGCAATGGCCAGTGTCTATTCCTCGAATGCCAGGCATGGTGCCATGTGCAGGGCATACGTGGTCCCTACCCTCATGCTGCCTGCAGACTCATGGTGAGAACATTAATCAAATACACCTTGACCTGGGGAAGCATTTAGTCACAATGCTGATGCCCTCCCTGGACAGGGCAGGACCCCGGCAGCAGGAGTGGCAGCCTAGTCCTCTTAGGACTGTCCCCTTGCCCCTGTTGCCCACCCTCCCTCCCCTGATGCTGTGCCCCTTGCTGCCAACAG
Seq C2 exon
CACGCACATTTGAAAACCTGGATGCCTGTGAGGTTCTCTTCTCCCCATCGCTGGCCACAGCTGCATCCCTGCTTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474:ENST00000409709:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(7.7=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(3.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTAACTGCATAACCTGTGAGGG
R:
CTCAAGCAGGGATGCAGCTG
Band lengths:
231-1247
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development