HsaINT0112604 @ hg19
Intron Retention
Gene
ENSG00000119408 | NEK6
Description
NIMA (never in mitosis gene a)-related kinase 6 [Source:HGNC Symbol;Acc:7749]
Coordinates
chr9:127055128-127064333:+
Coord C1 exon
chr9:127055128-127055292
Coord A exon
chr9:127055293-127064214
Coord C2 exon
chr9:127064215-127064333
Length
8922 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGA
5' ss Score
7.66
3' ss Seq
GCCGCTGTTTTCTGTTGCAGTTC
3' ss Score
10.51
Exon sequences
Seq C1 exon
GAGAAGAAGACACATGAATTAGAGACAGCACGGGGGAGCAGGCTGTGGAGCTGGGAGTGACGGGGTGAGTCCAGGAAGGCTGCCTGGAGGAGATGCCCAGGAGAGAAGTTTGCTGGGAGGCAGCTCATTTCCGGCAGGAGGAGCAGAGCCTGCCAAGGCCTCGAG
Seq A exon
GTGAGAGCAAGATCATTTCCCAGGCAGGCAGGGGTCTCTGGGATGGTGGGCCTGCTAGCGGGCCTGGGACTCCTAGAGTGAGACCGCAGCTCTCCCCAGCTGCATTGTGGTCACCAAGGATCACCTCAGGCAAATGATTAAAATGCAGACTTTGGAGAGGGTTGGATCTGAGTTCAAAAACAGGCCATGCTGCTTATCAGCTGCATGAGCTCGACAAGTCATTTAACTTCTCTGCACCTCAGTTTCTTCATCTGTAAAAGTGAAGGGCTTGCAGACCTCACAGCAGGGATGTGCTGAGCTGCTGCCTGCAGTGCCCGACACAGAGGAAGCACTCAGCAGATCTCAGCTTCATCTTCAGGGAGGCTGGGAGCGGACCCAGCCTTGACCAGGTCCCAGAGTCAAGAATCTTCTGGGCAGAAGCCAAATGCTTTGTTGCTCCTTTAACTGAGAGACAAGATGTTTACAGCTTCTGCATTTTTTTTCTTCCAGAATTGGGTTTTATTACCTGAGGAGGAAGTGAAAGGTGATTGGGATGCTCCTCGATTTTCAAAAAGGCCCTGGGAACCCTGCAGTGTGCGGCCCAGTTGGTTTTGAATCTCCAGTGACTTTTGTCTGATCTGTGACCACAGGGATGCTGAGCCCTCAGCAGAGGTTTCTTGGGGTTGCAGGAGGGTGGGAAGAGCCCCCTCCACCTACTAGTCAGAGATTCATTCTGCCAACGCCCCCTGGGTGGCCCTCTTTTCACCGGGCCTGGGTGAGGCACTGGAGGTTTACAGATGACCGCGAAGGTCAGTCCCTGCCCTTAAAGGCTGGCAGAGGAGGCAGACATGCTGACAAAGGAAGCAGTTTGTGTCCTCAACAGCCCACCTTCAGGGAGAAACCTGTGTAGATGCCACCAGATGGGAAAGGGAAGAAGGGGCCTTGGTGCCCCCTGGCTGCCCACTGTGTGCTCACAGAGTCCTCGCAGCCTCCCTGCAAGCTTGGGCTGTTCCTTTTTGTGGATGGGGACGTTTAAGGCTCAGGGAGGGGACGGGACTTCCCCAAGGTCCCACAAGAAGTGCCAAGACTATGGCTGGGCATGGTGGCTCACACCTGTAATCCCAGCACCTTGAGAGGCCAGGGTGGGAGGATCACCTGAGGTCAGTAGTTCGAGACCAGCCTGACCAACATGGCGAAACCCCGTCTCTACTAAAACTACAAAAATTAGCTGGGCGTGATGGTGTGTGCTTATAATCTCAGCTACTCGGGAGCCTGAGTAGTGTGTCAGTTCCTCCCTGCCAGCCAGTCTGCCTGGGCGTGGTAGTCCTTCCAGCCCCTGGGCTTGTGCTAAGTTTCTTTCTGTAATTGCTCCATCTGGCTGGTCTGAGAAGCAGGTTCAAATGGCAGGAGAATCACTTGAACCCAGGAGGCGGAGGTTGCAGTCAGCAGAGATCGCGCCATTGCACTCAAGCCTGGGCGACAAAGCAAGACTCCATCTCAAAAAAAAAAAAAAAGTGCCGAGATGAAGGAGGGTCGAGAGATCTGGTCCTGGCAGACAAGTGGGACTTTGCCCATTGAGAGGCACCGATGGGTCTTTAGTCCAAGGCTGGTGCATGGAATGACATGGAAGGACCAGGGTGCTGTGTTGCTGGGGAGGGGGACCGCTCATTTAATATGGCTGCACGCAAGGCCTGGGGGATGTTGGGGGCAAATGCATGAGGGCAGGCTCGTGTCAGGTGGTCAGGGAATGGCTTGCTCCGGTGTGCGGACCTTTTGCTGTGGAGTTTCAGGAGAGATTGGCAGGTTCAGGCTTGTGTGTTAGGAAAACCTTTCCATGGTGGGCTGGAGGCTGGGCTGCAGGGGAGTGTGGAGGCTGAAGGTAACTGTAGGGACCCAATGAGAAGGGACAAGGCCAGCACAGAGTGGAGGCCCTGGGGTGAGTGAAGACATTTGGAGGAAGAATGGTTGGGACTGGATGAAGACCAGGTGTGGGTCCTGGGGGAGGGCGAGGCATCCGGAGGCTACAGCAGCCCTGTTTCTGGGTGGGCACCGTGTGGCCCCCAATCAGCTGGCCTCCTGATGCTGCAGGCCCACCCTGGGGGAGGCCCCACCACCCTGAGGAAGGGGGCAGCGGGGAACCTGTCTGCATGGCCACCTTCCAGGAGTGGCTCATGGTCCTGCATCCCTGCACCTTAGAGCAGCCAGGCTTCCGCTGTCATGGAGCTGCAGAATCCGGGCAGGATGCTTGGCTTTGCAGGTGGAGAGCTGGGGCGAGCGTGAGGGAACACAGGACCCGGCCGGAAACCAGACTCCATCTGTGGCTTGTCCCCTCCAGCTTGACAGGCCCCCATGACTCTGGCCTGAGATCGGGCTGCTTCCTGTCAAGTGATGAATGGGCAACGTCTGCTTATCCTGAGACCAGACAAGAAGCGGGGCTGGGGCTGGGGAAGGGCCCAGCAGCCAGAGCCACAGCTCTGGGCCAGTATTCATTCAGTCAGTCATTTATTCACACCCTCTTCCAAGGCAGTTTGGACCAAGGCAGACTTGGTTTCGAGTGTCAGTTCTGCCTGCCGCCTGCTGTGTGACCTGGCACCCGTCACTCAACCTGTCTGAACTTTGGTTTCTCTTCTGAACAGTGTGGATCATAGCAGGGCCCGTCTAGGGGTCTGTAAGTGTGAACGAGGTATGAGCGGCACTGGGCACCTGCCTGGCGCATGTGTGGTGCATGCTCTGTTGGCGGGGGCTGTTATTCTGGTGCTCCCTGCCAGCCAGTGTGCCTGGGCGTGGCATTCCTTACAGCCCCTGGGCTTGCGCTGAGTTTCTTTCTGTAATTGCTCAGTCTGGCTGGTCTGAGAAGCAGGTTCAAATGGCAGCTCTCTCCACTGTGTGGACTCAACTTTGGCAAGCCATGTTTCTCCATGGAGCCTTAGTTTCCTCATCAACAAAACAAGGGTGATGGTACTTTGCAGGTGTCTTGGGAGATGCCGTTTCACCCGTGGATGTTGGCTGATGTTGAAGTTGGTCCGGCCTTGACCCAGCCAGTGGCCAGTGCAGTGAGCTGTCCTTGCCGGGCCTCCGATCTTCAGCTCCCTGGGGCATGTGTCGGGCAGTGGAGCCTCTGCAGGCTGGCTGAAGGCCCCAGGCAGTGGGCATCCATCCTCGGCTTCTGCCACCAGGAGCCAGCTGGACCAACAGACATCACCCCTGGTGCTGGCACTGGTGCTGCCAGTACCATTCGCTCGGGGCGGAGAGAAAGCTGTGTGTGCCTGAGTGTGAAGCCACAGGGACGGCTTCCTGCTTTAGGGAAAACAACCTGTGAAGCTGTGCCCTCGGCTGGAGGCACAGAGGAGGGGCCTTGCTCAGGGAAACTGGAGAGGGGAGTACAGTGTCTGGCCAAGGCTGACCTCCAAGGCCAGGAGTGGGTTCTCCCTGGGCTTGGCAACACCTGTCAGTCTGGGAGCCACAACTGCCTTTGCCACGTCTACCCTCTGCTTCAGTGGACAGAACGAGCCTGGTGGACATTAGATGACCCCTGATCATGCCTGTGCACGTGCACACACAGGAGCAGAAGAGGCAGGCAGGACACACACCGTTACCACCTCCAGGGTTCAGAGCAAGGAGAGGTGTAAGATCCAGTATATGAATGCACTTCCATGCATGGACCCCAGTACACATGGACCCTTGCAAGCTCATGCCCCCAAACCTGCTCCAAGCAGGGTCCTTGGACAGAGCCCTCCTGGTGTCTGAGGTCGTGCTTCACTGGCCGGGCCACGATGAGCCACCAGTCTCCATGAAGTGTGGCATTTGACAGGAGGCACAGGAATGACTTCCCCCTAGGTGAAGTTTCCAAAAATTCAGAGGCAAGGGCCCAATGACAGCCTTGGTCAGAAAGGCCACTTGGAACCTCAGAGCCAGCCCATTACAGCAGCCGATCCCTTCCAGCAGGTGCCTGGATTAAAACCAAGCGCTCATGTCTCCCTAGGGTCACAGCCCACATTAGTGAGAGCCTCATCCATGGCCGGGCAGGGTGCGGCACAGCAGCTGGCTTTGCAGAGGCAGCCACGGCTCACGTAGATGATGAAGACGTTTGCTCCAGAGCAGTCCTAAAGAGGCCATGCTGCGTAGGACATAGAGCAGCAATCTTGGGTCCAACAGCCCCAGCTGTGTCATTTACCAGCTGTGTTACCTGGGGCAGGGATGACCCTGGGCAAGTCCCTGCCTCAGGCCCCATGTCTGTCACATGGAGGTGATCACGCCTCCATTGTACAAGTGAGGGTTAGCTTCAATAGCTAAATAGCCTCATAGCTAAAGCCTCAGAGGTCCCTTCCCATGTGCCAGGCTCTGTGCTAAGGAGTTTACAGTGACCCTAAGAGGAAGATCTGACTGTTAGCCCATTTTCCAGATGAAGAAACTGAGACGCAGCATGGTTAGATGAAACCGGGCCAGGACCTGGACTCCTGCAGTCCAGCTCCCCGCCAGCCTCACTGAACCCTGAGGCTTCTCCCAATCTGGTCCCTCGGTGCCTGGGGACACACAGCACACGGCAGCCTAAAGCCAGGAACCTGAGCTGGGAAGCCTCACTGTGCAGCTATCCACAGTGTTTTGCAAATGTAGGGCCCTTGCTTGAGGCAGAAGAAAAGCCCTCTTTGAGGTGGTGTTCAGTGTGGCCTGCAGCTCTGGGTCTTGCATTCCATGGATTTTTGGCCCCTGACTTGGGCTTGGCAGCTACTACCTCATTGTTCTGCAACTTGGCAGGAGCCGCGGGATCCCGGGGACGGGCAGTCCTCAGTGTTACCCCGAGGTGCCTGCACGCATGTGCTAAGGGTCTTTTCCCTGCTCCGTGTGGCTCGTCCTTCCACGTCCCCTTTGCCTTGGCCTTTCTGCATCTGAACCCCCTAAGAAGCAGTTTCTGACAGGAATTTCCAGAGCACAGGGCTTGGGTTTCTGTTGGGGTGTGGACCAATAGAACAAAATGCCCTAAAATCCAATACCCATGGAGAGCCCCAAGAGGCAGTAGATTCCTTGGAACAAAGAGGGAGTTTAGAGTCACTGAGATCTGGATTTGAATCCTTTCTCTGCAGCTTATCAGCCTAATGGCATCGAGCCTCTTCCTCTGAGCCTCGGTTTCCCCATCTATAAAATGGGTCTACCAATAGCCCCGAGGGTGAATGGGAAAGACCTGGCCCACAGGAACCCTCATCCCTTCCTTTCTCCCTTCCTCCTTCCCCCTCGCGCCTCCCCACCTCCTTCCCCTCAGCAGGGACCCTCTCTGGCTCTCGGTGGGTAGGGGCTTGCAGAGTCCTCCGTGGCTGCTGCTTTCCTAGAACAGGGAACATCAACACCTGCCGGCTCCTCCCTGGAGGCTAACGGTGCCGCAGGTTCCATTAGGTTCTGAACAGAGCAGCTCGTAATGACTGGGGTTTGGCAGCAAAGGCACCACTGGGGTAGACAGTGGTGCTGCATCAGCTTGCTGTGGTCAGTGGGGCAGAGTCTCCGGGGGCTCCTGCCCCTGGGGACCCTGTGGAGGAAATGGGCCCTTGTGGTCCGCCAGCCCTGAGATCACCCCTGTGCATCAGCAGCACAGGCCCCATTCTCAAGTGGAGAGAGGGCCCATTCGGGGTGGAGCCAGCTGGAGAGATGATGGTGTTGCTGTGTAAGAACCTGTGGGGAGTGCAGTACCGTAGTTTTGGACAAATATGCAGTTGTTGGTTCAAATCCTGGCTCCTTTTGTCTGTGATCCTTGGGACCCGGGCAAATCTCTTAACCTCTTCGTGCCTCAGTTTTCTCATCTGTGAAATGGGACCATAATAGACCTTACCTCATGGAGTTGTTGACAAAATGAGATGGGCTAATAGAGGTGAAGAGCGTAGGGCAGGGCCCAGCATGATCAGGGCCCTGCAATTATTAGCTCTTATTCCCGGTCCCCCTTGCACTGCTCCTGGAGCCCTGCCCATGTGAGGCCACAGGTGAGCTCCTGAGAGTGTGCAGACCATGGCATCTGGCTGCAGCTGTTGGAGAATGCGGTCAGCGCCACGTGGGGAGGGCAGGAATGACATTCCCAAGCACCCGCTAGGCTCCTCCCCAGTGGGATTTGCCCAAGGTCTCAGCTGGTGAGTGACAGGGTCTAGATTCCACTGCCACAGTTTCCAGTACATGGGAGGCCCCAGGGCAGGTGGGCGGGTAAGCCGATGTGTGCATGGGTCTCGCAGGGGTGACCTGTGGGCCAAGGCTGGTGCCTTCTGAGATAAAGATGGAACCTTCTCACTGAAGACAGTTCTCCACTCTTTCCCTGGAGGTCTCCCTAAGGGCAGAGGACAGTGAGCATGTCACCCTGAGGGGTCTAGGGGTGCAGCTGGAAGCAGCTGCAGAGCCTGCAGGAGGCTCAGTTTTATCTTCAAATTCATGCGCATTTTACATTCTGCTCTCTCTCATATTCCCCCTAACAAAGATGCCTGGGGAAGGTGCTCGTGTTTATCTGTTTATCCTGGGGCTCTTTATACCCTGGGTCTTCCCCTGTGTCACCTTGGGATGTCACCTGCGCTCCAGTGCAAGAACTCGGCACAAATGGTGGAGACACCGAGGGTGCCATTTTCCCATCTGCATTTGAGGGCTTGGCAGGGAGAGCACTGAGCGCTGGGAGACCCAGGTGGGGAGATGAGGCCTGTGCTGAGGCAGAGGCAGGGGTGGGGAGGGAAGAGGCAGGTGCACCCATAATGCCCCTCCGTGTGACACTGATCTGACAGTGCTCTGTGTGCACAGACTAAAAAGACAACAAGAGACCTACTGACTGATCTGTCCACACTAGGATGAACCACATCAAATGGCCAAGTCTGTGGGTCAAAGTTGGTTGAGTTTCTGCAGCTTCCCAAGCAGGAGACTGCATGAGCCAGGCTTGGCAGGACTTGCAGCCAGCGAGGGCCCCCCTGACCCTGAGTTGGGCGTGTTCTGCAGTCCATACCATCCACTTCCCTGCAGTCTCACATCCTGTCATCTATTTTGAGAGAGCAGGTTTACCCCAGAACAGTCTGTGGAAGGTGTGGGGCAGGGAGGAGAGCTGGGCCGCCCTGAGGACACAGAGGGAGAAGGGTGCTGGGAGCCAGCCTGCAAGTTCTGGGGAGCCTCAGGGTGCCTTTGAGGGCACAACTTGGGAGGCCAAGCTCAGCGGGTGAGTTAGGGTTTGGTGGACATCCTTTGACATGTCAAAGGGTGTCACAGATATCCCTGGAGCCTGAGAGGTCTGGTCGGCCCACCACTGTGGCTGGAAACAGACTACAGTGGGGAGGAAGGAAGAGTGACTTGCACCCTGAGACACAGTGGCCGGACCTCTAGGAGCTGGCTGTGACAGCCCGGAGGGTGTTGATGCCTTTCCCACCTCCTGGAACACCCCCGTGTTAATGGGGGCGTGGGTCTACCTGGGAGGGAGTGGCAGGGCTGCTGGCCCAGCAGACCGGGGGAAGACTCTTGGTTTGGAATTTGACTGGGGCATAGGTGACCAGGTGAGACAGCAGGAGGCGGGGTCTGTCTGGAGAGAGATGACGTCTTTGGCTGGGTCCTCCAGAAGCCAAACTTGAGATGGGGATATGTAGGCATGGGATTTATGAAGTGCCCCTGGGAGAACCACTCAGGGAGGAGGGAGGGCAAGGCCAGGAATGGGCAGGAGACGGACCAGAGGTTCCTTCTCAGACAAAACCCGCTGACCGCGCCGGGGGCTCTAGGATACGAGTCACATCTTGGAGGGCCCCGACCTGAGACGGGACTGGCTTTCATTCTCGCCCCCTCAGCTGTTGAATAAGGGCCACCGCAGGGGAGGGGGCTCCATTCCTCAGGACTTCTGGCTCTCCAGGGGTACAGCTGAGCTGCTCCAGGAGCCTAGGCCAGGCCTCAAGGGGTTCTGCCTAGGATGTGGTCACATGAGAGGTGCCCCTCGGGACATCCAGGGCTTGTCTGGGAGAAGGAGCAGCAGCCAGAAACAGGGGCCCCATCACATGTGTGATCTAGTCCCTTCCATGCACACCATGTGGGAGCCCTGGCACACAGGAGGTGCTGCAGAAATGCTTGTGGGGTGAGCGCAGGTCTCTCCTTCTGGGGAGGAGGAGGGCTTTTCCCCTGGCATCAGGAAGCATCCCGGTGGCTGGGTCACACAGGTTCTATGCACATAACCTCAGACCCTGCCCCAGAAGCACTTGTCTGATGGGGGAGGCCAGAGGCTAAAATATTGGGGGAGATGCCCAGATGGCCTTGAGCTCAGGACTGGGCACACAGTGGGTGCTTAACCAGGGGCCTGTGGCTGCTGTGACTACCTATGACCAGCATCTCTGACTCTCCCAGGGCAGCCCAAGCCCTGGAGGCTGAGGGGGGCTGTTCCTTTGCACAGAGGTCTAAGTAGGACGGCAAACAGGACCTCTTGGCCCTGGCCTTCCCTGTGTCACACGTGTGGTGCGCCAGGGCCCAGCCAGGACAAGGACGTAGGTTCCTTCCCACAGCAGCTGTCTGCAGCCTGACCCAGGCCTTTCTCTTCTGAGCACCCAGGCTGCCAGCATGGGTATAGGTGGGGGTGACAATGGGGGATAGGGGTACAGAACTGCTCCCCAAGAAGCAGGGGCAGTGCTGTGGAAAGAACAAGTCTTTGGACTCCAGCAAATGTGGGGTTGAATCCGGTGTCTTCCTTCCTGGCCTTGGGGGCTGCTGATGGACGTTTCCCTGCCTGGAGCCTCTTCCAGTGGGGATAATCCTAGTGACTTAGGACAGTCTAACAGAAGGAGACTGTGTCACCCGGGGGTGTCAAGTTGTAGCCCTGCCACTTCGGAGCTGGGTGACCGTGGGCAAATTACTGAACGGCTTTGCACCTCAGCTCACGCATCTGTAAAATGGGGTGAGCGAAAGTCCCTCCTCCTTCTGAGGGTCTCAAAGAGAAAGTGAACAGGCCGCTGTTTTCTGTTGCAG
Seq C2 exon
TTCGTGCCCTCGTGAGGCTGGCATGCAGGATGGCAGGACAGCCCGGCCACATGCCCCATGGAGGGAGTTCCAACAACCTCTGCCACACCCTGGGGCCTGTGCATCCTCCTGACCCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119408-NEK6:NM_001166171:2
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.885
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0006920=Pkinase=PU(0.6=3.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)