HsaINT0120878 @ hg19

Intron Retention

Gene

ENSG00000105717 | PBX4

Description

pre-B-cell leukemia homeobox 4 [Source:HGNC Symbol;Acc:13403]

Coordinates

chr19:19680258-19681108:-

Coord C1 exon

chr19:19680918-19681108

Coord A exon

chr19:19680394-19680917

Coord C2 exon

chr19:19680258-19680393

Length

524 bp

Sequences

Splice sites

5' ss Seq

CAGGTCAGG

5' ss Score

7.2

3' ss Seq

GAAGGCGGCTGTTTTTGCAGGCG

3' ss Score

4.94

Exon sequences

Seq C1 exon

GCCTGTCGTGAGTTCACCACGCACGTCACCAACCTCCTCCAGGAGCAGAGCAGGATGAGGCCTGTCTCCCCTAAGGAGATTGAGCGCATGGTCGGCGCCATTCACGGCAAGTTCAGCGCCATCCAGATGCAGTTGAAGCAGAGCACCTGTGAGGCAGTGATGACCCTGCGTTCGCGGCTGCTCGATGCCAG

Seq A exon

GTCAGGGCCTGTACGTACCCAAAACCTCAAGGGCCGGCTCTGAGGGACTGGAGGGAAATAGTGCTGGCTTGGGTTGAAGACAGCCCTGGAGGCTGTGTCTGCAGTCACGGTTGGAGGCCTCACAGCCTCTTGGGAAGAAGGCCTGAAGTATTGCTGTTTTCATTTTTATTTTATTTTGTATTTATTTATTTATTTATTTGAGACGGAGTCTCACTCTGGTGCCCAGGCTGGAGTGCAGTGGTGCGATCTCCACTCACCACAACCTCCGCCTCCCAGGTTCAAGCGATTCTACTGCTTCAGCCTCCCGAGTAGCTGGGATTACAGGCTCCCGCCACCATGCCCAGCTAATTTTTGTGTTTTTAGTAGAAACGGGGTTTCACTATGTTGACCACGCTGGTCTCGAACTCCTGACCTCAAGTGATTGCTGTTTTCAGAACTACTGGAAAATCATACTCAGAACTAGAGGTGGGGGTGGTACTGGAGTCCCAGCATATTAATGCCTACGAAGGCGGCTGTTTTTGCAG

Seq C2 exon

GCGCAAGCGGCGGAATTTCAGCAAGCAGGCGACGGAAGTGCTGAATGAGTATTTTTACTCCCATCTGAACAACCCTTACCCCAGCGAAGAAGCCAAAGAAGAGCTGGCCAGGAAGGGCGGCCTCACCATCTCCCAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000105717-PBX4:NM_025245:4

Average complexity

IR-S

Mappability confidence:

NA

Protein Impact

ORF disruption upon sequence inclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.234 A=NA C2=0.239

Domain overlap (PFAM):

C1:

PF037928=PBC=PD(30.8=95.3),PF0076914=ERM=FE(39.1=100),PF070286=DUF1319=PD(62.5=85.9),PF040917=Sec15=PD(63.4=81.2),PF0044324=UCH=FE(25.8=100),PF0004624=Homeobox=PU(0.1=0.0)

A:

NA

C2:

PF0076914=ERM=FE(28.0=100),PF0044324=UCH=FE(18.4=100),PF0004624=Homeobox=PU(75.0=97.8)

Main Inclusion Isoform:

ENSP00000453348