HsaINT0121959 @ hg19
Intron Retention
Gene
ENSG00000186642 | PDE2A
Description
phosphodiesterase 2A, cGMP-stimulated [Source:HGNC Symbol;Acc:8777]
Coordinates
chr11:72290328-72290652:-
Coord C1 exon
chr11:72290578-72290652
Coord A exon
chr11:72290428-72290577
Coord C2 exon
chr11:72290328-72290427
Length
150 bp
Sequences
Splice sites
5' ss Seq
AAGGTGATG
5' ss Score
5.22
3' ss Seq
CACCCCTGCCCTCGCCTCAGGAC
3' ss Score
8.36
Exon sequences
Seq C1 exon
AGGCACCACTTTGCTCAGGCCATCGCCATCCTCAACACCCACGGCTGCAACATCTTTGATCATTTCTCCCGGAAG
Seq A exon
GTGATGGGGTTGGGGGTGGGGTGGGGATTGAGGGGGAGCTGGGAGCTGGCTGGAGGTGGGATAAGGAGCCAAGGAGTGGAGGCTCACTGGGATGGGCAAATGGGTGGGGGTGTCCAGTAGGAGGGCATGACACCCCTGCCCTCGCCTCAG
Seq C2 exon
GACTATCAGCGCATGCTGGATCTGATGCGGGACATCATCTTGGCCACAGACCTGGCCCACCATCTCCGCATCTTCAAGGACCTCCAGAAGATGGCTGAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186642-PDE2A:NM_001146209:27
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=FE(10.1=100)
A:
NA
C2:
PF0023314=PDEase_I=FE(13.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACCACTTTGCTCAGGCCATC
R:
CTTCTGGAGGTCCTTGAAGATGC
Band lengths:
162-312
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)