HsaINT0122170 @ hg38
Intron Retention
Gene
ENSG00000133256 | PDE6B
Description
phosphodiesterase 6B [Source:HGNC Symbol;Acc:HGNC:8786]
Coordinates
chr4:663100-663870:+
Coord C1 exon
chr4:663100-663187
Coord A exon
chr4:663188-663769
Coord C2 exon
chr4:663770-663870
Length
582 bp
Sequences
Splice sites
5' ss Seq
GAGGTTGGT
5' ss Score
6.36
3' ss Seq
GCTGGGCATAACCTCCGCAGACC
3' ss Score
5.15
Exon sequences
Seq C1 exon
GTCCCAGAACCCCTTGGCTAAGCTCCACGGCTCCTCGATTTTGGAGCGGCACCACCTGGAGTTTGGGAAGTTCCTGCTCTCGGAGGAG
Seq A exon
GTTGGTATACTCACCCTCGGTTTCTGCTGTGGGCGCTGGGGACGCAGCGTCCGCAGGACGGCAGGGCCGTATCCTGCGGAGCAGGGTTCTGATGCAGCGGGTGAGCACTGGGTGTGTGAGCACTGGGGGAGGGCGGCAGAGAAGGCGGAGGGCCGAGGCTGAGGGCAGGTGCATCGGAGGCCCTGGGAAAACGCTTGTGGGGAAGACAACTGGAAAGGGCCCCTCATGGGGTGGGGTGGAAGCCGAAGGGGAAGCGGCCCGGGACCCACCAGCGGGGGAATGAAGGGCAGCCGAGCCCTGAGCGGCCCCCAAGGACCTGGACACTCAGTGGACCCCTCCCTGCGCTCCCCGGTGGTGACCTCTGAGGCCATCTGCGTCCCAAGCCGACGATGGAGCCGCTGGTGGAGAGCTGGGCACCCTGAGGAGGGCCCTGAGCAGCAGGCGGATTAGGGGTCCCGCCCACCGAGGGCCCGAGGGCGGGGGCGTGAGAGGCACAGGCAGCCGAGGCGGAAGGGGCGGGGTCCCCGGGCACCCTGAGAGGTGGCCGCAGGGCGCCTGACGCGCTGGGCATAACCTCCGCAG
Seq C2 exon
ACCCTGAACATCTACCAGAACCTGAACCGGCGGCAGCACGAGCACGTGATCCACCTGATGGACATCGCCATCATCGCCACGGACCTGGCCCTGTACTTCAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133256:ENST00000255622:15
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=FE(11.6=100)
A:
NA
C2:
PF0023314=PDEase_I=PU(22.9=97.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGAACCCCTTGGCTAAGCTC
R:
TTGAAGTACAGGGCCAGGTCC
Band lengths:
185-767
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development