HsaINT0122176 @ hg38
Intron Retention
Gene
ENSG00000133256 | PDE6B
Description
phosphodiesterase 6B [Source:HGNC Symbol;Acc:HGNC:8786]
Coordinates
chr4:666531-668006:+
Coord C1 exon
chr4:666531-666614
Coord A exon
chr4:666615-667855
Coord C2 exon
chr4:667856-668006
Length
1241 bp
Sequences
Splice sites
5' ss Seq
AAGGCGAGT
5' ss Score
2.72
3' ss Seq
GACTTCTCGACTCCCCTCAGGAG
3' ss Score
6.79
Exon sequences
Seq C1 exon
CCTATGATGGACCGGAACAAGGCGGCCGAGCTCCCCAAGCTGCAAGTGGGCTTCATCGACTTCGTGTGCACATTCGTGTACAAG
Seq A exon
GCGAGTGGTTCACGGGTGTTCCGAGCTGACTGGGGCAGGGTGGCTGGGAGCAGGCAAGGGGGCGCGGGCTGGAGTCGCGTGGACTCACACGGGCCCGGCGGTGTCCTCACTGGAGTAGGGATGCCAGTGCCAGCTTCGTGCCGCTCTTGAGTGGGGCAAATGGGGAGGAACATCAGTTTCCGGACCCCCACAGGTGCCCCAGCCCATCCTCACCCTGCTGTGCCCCTGGAAGCTCTGAGCCCTTTCCCAGCCCAGAATGTCCTCTGCTAGCCTCCAGGCCTACCCCAGAAGTTCTCCCTCAGTGCCCTCCGCCGTGGCCAGCACACTGTTTTGGGGGCCTTGGCTGCAGCTCTGTGGGTTCATTTGTTCCATGTTTGTGAACCCTCGAGGCGGGGCTGGGTCGGCCTGTCTGCTGGTGCACCCGCCCACAGGGGCGTTTGGAACAGCAGAAGGAGCCACATCCCTGCCAATCTGCCACAGTCCGATGCCAGCTGAGTCTCTGAGGACGCAAGGCGGACATGGAGGGGGAGACTCGATGGGGCAGGGGTCTGACCGTGGGGCCCTGTGTGATGCCCATAAGAGCCAGCTGCCTCCGGCCACACTCCCTGGTGATGGAATCCACGCCCCAAGGAGGATGCCACGGGTTCCACATGAAGTTGTCCCGGAGTGGGCTGTGCCCACTCCCCGCCCCATCCTACCCACCCCGGGTCGTCAGTGCTGGGGAGAAGGTGGGACAAGGGTGGATATTTGGGCCTGAAGTGGCCACAGGTCACGGCCCCACTGCAGGTGCCCCCCACTGCCTTCCCCACCCCGCCACACTCCATGTGTGATGTGCGCGAGTGCACGCGTGTGCTGTGCTTGCATGATGTGTGCCGTGTGTGTGTGGGAGGGACGGGAGAAGGCACTGCAGGGGCTGCCTGCTGTCCGCCTGTGCCCACCACCCCTCTGCCTGGCACCCTGCCCCCACCCCCTGAGCTGTTCTGCTCATTCTTGGGTTCCTCTCCCTGCAACACTGCACCCTAAGCATGCATACCCTAAAGCTCCCGGCTTCAATGTCACCAACACAGCCCCCGAGGTTTCTCCCTTCACAGGGCTCTGCTGGGAAGGTGCCCCCTCCGTGGCGCTCCCTCCTCCTGCCAGGCAGTTCATCCCCTACGAGGGGGATGAGCTGGGGAAGGGCTATCTTACTCTGGAGAGAGCAGGCAGGACAGGACTGGTGGTGACTTCTCGACTCCCCTCAG
Seq C2 exon
GAGTTCTCTCGTTTCCACGAAGAGATCCTGCCCATGTTCGACCGACTGCAGAACAATAGGAAAGAGTGGAAGGCGCTGGCTGATGAGTATGAGGCCAAAGTGAAGGCTCTGGAGGAGAAGGAGGAGGAGGAGAGGGTGGCAGCCAAGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133256:ENST00000255622:20
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.031
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=FE(10.8=100)
A:
NA
C2:
PF0023314=PDEase_I=PD(23.5=66.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TATGATGGACCGGAACAAGGC
R:
CTTTCTTGGCTGCCACCCTC
Band lengths:
233-1474
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development