HsaINT0122180 @ hg19
Intron Retention
Gene
ENSG00000133256 | PDE6B
Description
phosphodiesterase 6B, cGMP-specific, rod, beta [Source:HGNC Symbol;Acc:8786]
Coordinates
chr4:648613-649795:+
Coord C1 exon
chr4:648613-648677
Coord A exon
chr4:648678-649728
Coord C2 exon
chr4:649729-649795
Length
1051 bp
Sequences
Splice sites
5' ss Seq
TCCGTAAGT
5' ss Score
10.27
3' ss Seq
CCCCTGCTCTCTGCCCACAGCAC
3' ss Score
11.83
Exon sequences
Seq C1 exon
GAAATTGTCTTCTACAAAGTGATCGACTACGTCCTCCACGGCAAGGAGGAGATCAAGGTCATTCC
Seq A exon
GTAAGTGCAGGATTTTACCAGAAGCGTCCCCGGGGGAGGGACCGCCCCTCAGACCCCGGCTCAGCCCCCAGGGCCGTCCTCCCAGGGCTTCCCACGGTGCAGTCAGCAGCACCGGCCTGGCCTGGCCCCACCTGTGGTGCTCTGTGTGCCGTGGGGCATAGTGGAGTTGGGGGTGAGACAGAAGCCGACTCACTGTTCTGGGAGATGGTGAGGAGGACGTGGGCTGCTGAGGAGCCCGAGTCACTGTGGACATCCAGAGTGGACATACAGGGGACCAGGCAAGCTGTCCAGGCGGCCTCGTCAGCAACAATTGAGCATGAAGGCCCCAGGATTTGACCCTGGCACCACCAGCCCCACCCAGACAGTGGAGCCTCCAGCCAGGAGGCCGAGTCTTGGCCCCGTGGGGCTGGAAGAGGAGGGGAACTCCAGTCCGGAGGTCAGGGCAGGACTCCAGCCAAGGGAGGGGCAGCTGGTGGCCCAGTGGCCCTGTGATCCCATAAGCCTATTGGGACCCCATCCCCAGGCCCCAAGCAGGAACCAGGATCCAGGTGCCAGGCTTGAGCACAAGTCAGGGTCAGGGTGGCAGGGCAGGCACCAACGCTGAGTCCTAGAAAGCAGGCTGAAGCCATACGGCCTCCGGAGAGGGAGGGGTTCCCAAGAGGGAGGGGCCCCAGCACGGCAGCCTGGGGAGGAGGAAGAAGGCAGCACAGCCGTCCTCCAACCCACGCCCTGGCCTCCTCGCCTCCTGAACCCCCTGGCACTCAGAGAAGAGAGTAAATGCTGAGGATGGCACATGAGCCAGAGACCCCCAGACCCCTGCACACACGCCCAGTCCATCTGACCCCAGTACACCTACATCCAGCGCAGCCTGGCCCCTCTGACCCCTGCACACACACGTGCAGCCCAGACCAGCCCCTCTGACCCCTGCACACACACGTGCAGCCTAGACCAGCCCCTCTCACCCCTGCACACAGACATCCAGTCCCTCTGACTCCTGCACGCGCACATCCAGCCCGGCGTGGCCTATCTGACCCCTGCTCTCTGCCCACAG
Seq C2 exon
CACACCCTCAGCCGATCACTGGGCCCTGGCCAGCGGCCTTCCAAGCTACGTGGCAGAAAGCGGCTTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133256-PDE6B:NM_001145291:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0159021=GAF=FE(11.8=100)
A:
NA
C2:
PF0159021=GAF=FE(12.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)