HsaINT0125318 @ hg38
Intron Retention
Gene
ENSG00000186088 | GSAP
Description
gamma-secretase activating protein [Source:HGNC Symbol;Acc:HGNC:28042]
Coordinates
chr7:77329333-77330367:-
Coord C1 exon
chr7:77330239-77330367
Coord A exon
chr7:77329392-77330238
Coord C2 exon
chr7:77329333-77329391
Length
847 bp
Sequences
Splice sites
5' ss Seq
GAGGTATGA
5' ss Score
8.55
3' ss Seq
TGACGTGTTCTCACTCCTAGAAA
3' ss Score
9.07
Exon sequences
Seq C1 exon
GTGCTCAGCTTTAAGGGCTACTGGGAAAAACTGAACTCCAACCTAGAATATGTTAAGTACGCCAAGCCACACTTCCACTATAACAACAGTGTGGTCAGGAGAGAGTGGCACAACCTGATCTCTGAAGAG
Seq A exon
GTATGAGTGGGTCAGTGAGAACAAAGCCAGCAGCGAGGCATAGTGGACTGGATCCAGGTGATGCCTTTAAATCATAAGGCTGGCTTCCATGTGCAGCACTCTTCCCAATTGCCAGGGACTTGATCATTGTCATTACTGATCTCAATGGGCAGAGATGCTTCTATGATCTCTGTTCTCCTAGGGAGGAAACTGAAAAGCAGAAAGTTTAAGGGGACACACAGCACATTCATAGTAGAAGTATGATTAATATCCATGTCTCAGATGTGTTCTCAGGTTACTTATGTAGTTAAAAATTGATATTAAAAAATCTAGGTGTTCCCAACTTAGTGGTCATTAGGGGTTGGGGTAGTTGGAGGGAGAATAGTGGACGTGACTCACTGTCCAGGGGTGACCCAGGGAAATCTTTGGGGGTGATCGAAGACTTCTATGTGTTGATTGTGGTGGTACATTGTGGGACATGAATCTAAACATGATAAAATGACATAGAATGACACACACACATTGTGCCAATGTCAATTTTTGATTTTGATATTGTGCTCTAGTTAGGTAAGATATAAGCACTGAGGAGACTGGGTGGAGGGTACATTGCATCTCTCTCTAGTATCGCTGCATGTAGATTAGTGTTGTTGTGTGTAGTATATAGTTGACTCGCAGTTTCCTGTGAATCTGTAATTGTTTCAGAATAAAATATTTCTTAAAACTTTAAAAAAAATCTAGGTGTTCTGATTACCTGGAAAGTATATTTCTTCTCTCTGATGCTCTTAACTGTATTGCATTATATCCTTGACGTGAAAAGTCACCGATAAAACCTTTACCTTCCACATTTCTGACGTGTTCTCACTCCTAG
Seq C2 exon
AAAACAGGAAAAAGAAGGTCTGCGGCATACGTGAGGAATATTCTTGATAATGCAGTAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186088:ENST00000257626:20
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTCAGCTTTAAGGGCTACTGG
R:
CTGCATTATCAAGAATATTCCTCACG
Band lengths:
182-1029
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development