HsaINT0127556 @ hg38
Intron Retention
Gene
ENSG00000122194 | PLG
Description
plasminogen [Source:HGNC Symbol;Acc:HGNC:9071]
Coordinates
chr6:160736887-160738612:+
Coord C1 exon
chr6:160736887-160737007
Coord A exon
chr6:160737008-160738537
Coord C2 exon
chr6:160738538-160738612
Length
1530 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGA
5' ss Score
10.57
3' ss Seq
GAACTAAATCCTCTTTCCAGGTT
3' ss Score
8
Exon sequences
Seq C1 exon
CGGCCCCTTCATTTGATTGTGGGAAGCCTCAAGTGGAGCCGAAGAAATGTCCTGGAAGGGTTGTAGGGGGGTGTGTGGCCCACCCACATTCCTGGCCCTGGCAAGTCAGTCTTAGAACAAG
Seq A exon
GTAAGAACAGGCCCAGAAACGATTTATACTGTCCCTCCACGTAAGCCCTGCAAAACCCTTCTACATTTACATAAAATCCACACAGCTGAGGCATCAGCACCTGCCTCTAAGTTTTCTGAAGGAGGAAAAAAGCTACAAAAATTAATATATGTATATATACATATATATTTTTATAGGTTCTCTACTGTGAAAATGACAAAAATTGCTGTCTTTTTCTTGATCTGGGCAGCTCCATCAAAATCTGTAGGCACAGTGATTTGCACCAAGTTCCAATATTGCTGGAAAATACTGAAGATGCTCTGAGGATTTCTATGGATATCCATTGTCTCATTGTCAGATGAAAAGAGGGGGAAGTTTTTAGAAATGTGACACTTTCTGGGTTGGGAGAGCAAGGACAAAATTATCTCCAGTCTATCACAGGCACAGATTCTTTTTCTTTGGACACTTTCGTGAATCATTGAATTCAATGCAGAGGCTACTCATCCATTCGCAAACAAAAAAATTCTAGGTCATGATCCCCATAAATGAAGAGTGATCAGTCCAATCCCAGGGAACCTGGACATTTTGGGTATTGTTTCAGTGGAACATGCCTTTCATAAGTTCCATTTTCTTGGGTATCTCTTAGGAAGCAAGCATAGGAAACAGGCCCATCCGTCTGCCTGTTTTGCTTCCTCATCTCACTTCTACACGAGGGTGCCTGTGCTCAATTGCTGTTTTCCCCTAAAGAGACTCTTTTCCATAAGTTTGTGAAATGCCATCGACAAACCTGATCGCATTGCATTTCACTCTGCTGTTGAGTCGATTTTTCTTTATTTTATCATTTAGTAACTCCTTGCTCTACAGAGCTTTCACCTTCCACATATTTCAGATTCATTCTTTCCTAAACTATGTGGTGGTCTACGTCCTCACTGACTTATCAACATGCTACCATCATGCACTTCCTATCTCTATTCCTCTTCTTTAAATTTGGTTCCAAATGGCTCACACCATTATTCTGAGCTATTACCTGCCTACGCAGTCCTAGAAAGTAAGTGATTCAGGAAACATTCCCCAAAAGTAAAGTTTCTCAGGTAAGATCAGAAGACTCCCATGAGTCACTGCTGCTCAGGATCACATCTGGCTCCTTGAAGAGTGATTCATCAGACCTTACATAGATCTTGTCATAAAAATGAAAGAGGCCTCGGGGGAAGGTCTTGGGCTGGTGGCTTCTGTTGGAGTCCTGGGCTGTGGGGTGAAAGCCGTGGCTGTAGAGCTTCATGCGGAGTTACTTAGCTTTGCTCTCCTGTGGACAGGCCATGCCTGTGCCTCCCCCAAGCATCGGAAAAATTGGCATAGATGGGCCCTTCTCAAAAATCCCACTCCTGGAGCACTGGCCAAAATTACTACCATCCTGATGCTGGGCTTGCAGTCCTTTCCTTTGGGAATATGAACATGGTCAAAATTAAGTGAACGTGTCTTTCTGGCTTTCTGTACAATGGAGCAGAACAAAGTATCAATTTAACTAAAATTTGAACTAAATCCTCTTTCCAG
Seq C2 exon
GTTTGGAATGCACTTCTGTGGAGGCACCTTGATATCCCCAGAGTGGGTGTTGACTGCTGCCCACTGCTTGGAGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000122194:ENST00000308192:14
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(9.0=48.8)
A:
NA
C2:
PF0008921=Trypsin=FE(11.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGCCCCTTCATTTGATTGTG
R:
CAGTGGGCAGCAGTCAACAC
Band lengths:
187-1717
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development